Cancer News

Yale Researchers Identify a Key Link between Tumors and Healthy Tissue

March 21, 2014

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Researchers from the Yale School of Medicine have discovered a key link between tumors and healthy tissue, revealing a potential mechanism used by cancer cells to recruit healthy cells to promote tumor growth. The delicate balance between development of normal tissue and tumors depends in part upon a key molecular switch within cells, Yale School […]

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Scientists Sequence the Genome of the World’s Oldest Continuously Surviving Cancer

January 24, 2014

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Researchers have sequenced the genome of an 11,000-year-old dog cancer, revealing its secrets and origin. Scientists have sequenced the genome of the world’s oldest continuously surviving cancer, a transmissible genital cancer that affects dogs. This cancer, which causes grotesque genital tumors in dogs around the world, first arose in a single dog that lived about […]

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Scientists Develop a New Way to Kill Cancer Cells

November 1, 2013

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By targeting mitochondria with the anticancer drug cisplatin, chemists have developed a new way to kill cancer cells that have shown resistance to cisplatin. Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively by damaging nuclear DNA, but if tumors become resistant to cisplatin […]

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Gold-Plated Nanoparticles Seek and Destroy Cancer Cells

October 16, 2013

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In a recently published study, researchers from Cornell University detail how they developed gold-plated nanoparticles that are able to find and destroy cancer cells. Comparable to nano-scale Navy Seals, Cornell scientists have merged tiny gold and iron oxide particles to work as a team, then added antibody guides to steer the team through the bloodstream […]

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Scientists Uncover a Pathway for Silencing Tumor Suppressor Genes

October 10, 2013

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Researchers have identified a RAS-regulated pathway that initiates and maintains the epigenetic silencing of tumor suppressor genes in mice, a finding that may help provide personalized therapy for RAS-mutant cancers. When genes that normally suppress tumor growth are themselves suppressed, cancer cells can grow and proliferate uncontrollably. A new study led by a researcher at […]

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New Genome Analysis Reveals Dozens of Cancer Triggers

October 4, 2013

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A new analysis of little-explored regions of the human genome has revealed dozens of cancer triggers. A massive data analysis of natural genetic variants in humans and variants in cancer tumors has implicated dozens of mutations in the development of breast and prostate cancer, a Yale-led team has found. The newly discovered mutations are in […]

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Stanford Scientists Are Developing a Mini-Microscope to Detect Cancer Cells

October 1, 2013

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Stanford scientists are developing a mini-microscope to noninvasively detect circulating tumor cells, allowing for earlier interventions. One of the cruelest truths about cancer is that even after you beat the disease, it can still come back to kill you. A tumor growing in the prostate gland, breast, or any other organ can shed cancerous cells […]

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Therapeutic Cancer Vaccine Begins Human Clinical Trials

September 6, 2013

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A Phase I clinical trial of an implantable vaccine to treat melanoma has begun. A cross-disciplinary team of scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer. The effort is the fruit of a new […]

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Inactivating AGPS Enzyme Reduces Tumor Growth, Cripples Cancer Cells

August 27, 2013

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In a newly published study, researchers tested the effects of reducing ether lipids on human skin cancer cells and primary breast tumors, finding that inactivating an enzyme critical to the formation of ether lipids substantially reduced the aggressiveness of the cancer cells. Berkeley — Knocking out a single enzyme dramatically cripples the ability of aggressive […]

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Research Shows NEETs Are Prime Suspects in Breast Cancer Proliferation

August 20, 2013

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A newly published study from an international team of scientists found that reducing the expression of a pair of proteins known as NEETs, NAF-1 and mitoNEET, significantly reduced cancer cell proliferation and breast cancer tumor size. Two proteins have been identified as prime suspects in the proliferation of breast cancer in a study by an […]

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p27: A Marker for Breast Cancer?

August 12, 2013

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Researchers are in the final stages of testing p27, a mammary gland progenitor marker that they believe could lead to the commercial development of a clinical test for breast cancer risk. An international scientific collaborative led by the Harvard Stem Cell Institute’s Kornelia Polyak has discovered why women who give birth in their early 20s […]

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Deltarasin Blocks Oncogenic Protein KRAS, Opens Up New Approaches to Cancer Therapy

August 8, 2013

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Scientists at the Max Planck Institute have discovered how Deltarasin prevents the transport of the oncogenic protein KRAS to the cell membrane, opening up new approaches to cancer therapy treatment. One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite […]

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