Cancer News

Yale Study Reveals How a Cancer Gene Promotes Tumor Growth

June 27, 2016

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How a Cancer Gene Promotes Tumor Growth

A new discovery by Yale researchers may help lead to individualized treatments for lung cancer and other types of cancer. A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with […]

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Yale Study Finds Racial Differences in Smoking Patterns

March 15, 2016

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Study Finds Differences in Smoking Habits between African Americans and Whites

A newly published study from Yale University reveals that differences in smoking habits between African Americans and whites may lead to a disparity in screening for lung cancer. The paper was published online March 15 in Nicotine & Tobacco Research. Cigarette smoking, the leading cause of preventable death in the United States, has been widely […]

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Yale Study Shows Key Protein In Pancreatic Cancer Growth May Also Be Its Undoing

March 14, 2016

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A New Target for Attacking Pancreatic Cancer

In a newly published study, Yale scientists reveal that the overexpression of a protein called renalase in pancreatic cancer plays a critical role in spurring the cancer’s growth while also providing a possible new target for attacking the tumors it helps develop. Pancreatic cancer is one of the deadliest cancers, causing about 40,000 deaths annually […]

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Scientists Reveal Amino Acids Supply Most Building Blocks for Tumor Cells

March 8, 2016

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Amino Acids Supply Most Building Blocks for Tumor Cells

New research shows that amino acids, not glucose, account for the majority of cell mass in proliferating mammalian cells. Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar. Scientists had believed […]

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MIT Research Shows How Diet Influences Colon Cancer

March 2, 2016

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MIT Study Shows How Diet Influences Colon Cancer

New research from MIT reveals ties high-fat diet to changes in intestinal stem cells, helping to explain an increased cancer risk. Over the past decade, studies have found that obesity and eating a high-fat, high-calorie diet are significant risk factors for many types of cancer. Now, a new study from MIT reveals how a high-fat […]

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Yale Researchers Identify Gene That Regulates the Growth of Melanoma

February 29, 2016

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Yale Identifies Gene That Regulates the Growth of Melanoma

New research from Yale University identifies a gene in melanoma that can dramatically affect the growth of the disease. The findings, published in the journal Cell Reports, provide new insight into how melanoma grows and identifies a new target for treatment of melanoma and other cancers. Enzymes that chemically modify DNA, known as DNA methyltranferases, […]

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Yale Scientists Reveal Underlying Cause of Myeloma

February 11, 2016

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Yale Scientists Discover Underlying Cause of Myeloma

Scientists from the Yale Cancer Center have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published February 10 in the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated. Multiple myeloma is a cancer involving the growth of plasma […]

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Immune Therapy Drug Prolongs Survival in Advanced Lung Cancer Patients

December 21, 2015

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Immune Therapy Drug Shows Promise in Fight Against Cancer

A newly published study involving patients with advanced non-small cell lung cancer resistant to chemotherapy has found a promising weapon in an immune therapy drug commonly used to treat other cancers. The findings were published December 19 in The Lancet and presented at the 2015 annual conference of the European Society for Medical Oncology in […]

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New Research Reveals How Cancer Cells Escape Blood Vessels

December 16, 2015

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Scientists Reveal How Cancer Cells Escape Blood Vessels

A newly published study from MIT and Massachusetts General Hospital reveals how cancer cells latch onto blood vessels and invade tissues to form new tumors — a finding that could help researchers develop drugs that inhibit this process and prevent cancers from metastasizing. Cancer cells circulating in the bloodstream can stick to blood vessel walls […]

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Yale Researchers Discover New Complexities Behind Drug Resistance

December 10, 2015

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New Study Probes Genes for Clues to Drug Resistance in Aggressive Breast Cancer

New research from Yale University probes genes for clues to drug resistance in aggressive breast cancer. By sifting through the 20,000 protein-encoding genes in the human genome, Yale researchers discovered new complexities behind drug resistance and identified patterns of mutations that could predict which therapies will benefit patients with aggressive breast cancer. The findings will […]

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Scientists Develop a New Way to Deliver MicroRNAs for Cancer Treatment

December 8, 2015

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Researchers Develop a New Way to Deliver MicroRNAs

By twisting RNA strands into a triple helix and embedding them in a biocompatible gel, researchers from MIT have developed a new way to shrink tumors in mice with an aggressive form of breast cancer. Twenty years ago, scientists discovered that short strands of RNA known as microRNA help cells to fine-tune their gene expression. […]

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New Strategy to Better Protect Cancer Patients from the Flu

December 7, 2015

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New Vaccine Better Protects Cancer Patients from Flu

Scientists from Yale University have developed a new vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented December 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida. Patients with cancers of the immune system, like multiple myeloma, […]

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MRI May Lead to Overdiagnosis of Cancer

December 2, 2015

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MRI May Lead to Overdiagnosis of Cancer for Older Women

New research from Yale University details how magnetic resonance imaging (MRI) for many women undergoing breast cancer surgery might identify health problems that would not otherwise impact patients — or lead to “overdiagnosis.” Published in the Journal of Clinical Oncology, the study examined whether preoperative MRI use would allow doctors to identify breast cancer in […]

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A New Paradigm for Cancer Research, One That Focuses on Improving Efficacy and Value

November 5, 2015

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A New Paradigm for Cancer Research

A newly published study from Yale University tackles the issue of value in cancer research, recommending a new paradigm for research that focuses on improving efficacy and value, as well as ensuring population health impact and generating new knowledge. The $100 billion federal government investment in the “War on Cancer,” has produced only relatively modest […]

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Rare ALK Genetic Mutation Extends Cancer Survival

October 15, 2015

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Rare Genetic Mutation Extends Cancer Survival

A new study from Yale University reveals that patients with the rare ALK mutation are living an average of four years, compared to typical patients that die of NSCLC within seven months. Most patients with non-small cell lung cancer (NSCLC) that has metastasized to the brain have a dire prognosis. But Yale researchers have identified […]

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Bioadhesive Nanoparticles Help Protect Your Skin From the Sun

September 28, 2015

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New Sunblock With Bioadhesive Nanoparticles

Dermatologists from Yale University have developed a new sunscreen made with bioadhesive nanoparticles that doesn’t penetrate the skin, eliminating serious health concerns associated with commercial sunscreens. Most commercial sunblocks are good at preventing sunburn, but they can go below the skin’s surface and enter the bloodstream. As a result, they pose possible hormonal side effects […]

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Brazilian Wasp Venom Kills Cancer Cells Without Harming Normal Cells

September 2, 2015

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Brazilian Wasp Venom Kills Cancer Cells Without Harming Normal Cells

A newly published study shows how Brazilian wasp venom selectively kills cancer cells without harming normal cells. The social wasp Polybia paulista protects itself against predators by producing venom known to contain a powerful cancer-fighting ingredient. A Biophysical Journal study published September 1 reveals exactly how the venom’s toxin–called MP1 (Polybia-MP1)–selectively kills cancer cells without […]

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New Model Captures Shape and Speed of Tumor Growth for the First Time

August 31, 2015

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Model Captures Shape and Speed of Tumor Growth for the First Time

Scientists at Harvard have developed the first model of solid tumor growth that reflects both shape and growth. They’re among the most powerful tools for demonstrating how cancer grows and spreads, but mathematical models of the disease have always faced an either/or problem. Models for capturing the spatial — or 3D — aspects of tumors […]

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