Cancer News

Take Time to Protect Your Kids’ Skin Now, It Could Prevent Cancer Later

July 31, 2015

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Protecting Kids’ Skin Now Can Prevent Cancer Later

Dermatologists stress that protecting your children from the sun now can help prevent cancer later. More parents appear to be vigilant about protecting their children from the sun’s harmful rays—at least at Yale Dermatology-Middlebury where Brittany Craiglow, M.D. practices. Many parents tell Dr. Craiglow they’ve started applying sunscreen so early in their children’s lives that […]

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Gene Therapy Gives Ovarian Cancer Patients Hope

July 28, 2015

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Gene Therapy Improves Survival Rates in Patients with Ovarian Cancer

A team of researchers from Harvard and Mass General Hospital has found a gene therapy that delivers a protein which suppresses the development of female reproductive organs, possibly improving the survival of patients with ovarian cancer that has recurred after chemotherapy. A gene therapy that delivers a protein that suppresses the development of female reproductive […]

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Pharmaceutical Firms “Underinvest” in Long-Term Cancer Research

July 28, 2015

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Do Firms Underinvest in Long-Term Cancer Research

A newly published study from MIT and the University of Chicago reveals that pharmaceutical firms “underinvest” in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research. Specifically, drugs to treat late-stage cancers are less costly to develop than drugs for earlier-stage cancers, partly because the […]

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Yale Scientists Reveal ‘Major Player’ in Skin Cancer Genes

July 27, 2015

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NF1 Identified as Major Player in Skin Caner Genes

Researchers from Yale University have confirmed that a gene known as NF1 is a “major player” in the development of skin cancer. A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed […]

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Yale Study Shows T Cell Lymphoma Caused by Gene Deletions

July 21, 2015

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Study Shows T Cell Lymphoma Caused by Unusually Large Number of Gene Deletions

A newly published study from Yale University shows that a deadly form of T cell lymphoma is caused by an unusually large number of gene deletions, making it distinct among cancers. Researchers conducted a genomic analysis of normal and cancer cells from patients with cutaneous T-cell lymphoma, a cancer of T-cells of the immune system […]

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Diabetes Medication Could Be Used to Reduce Tumor Growth

July 14, 2015

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Diabetes Medicine Could Reduce Tumor Growth

Researchers from UCLA have identified a new mechanism that delivers glucose to cancer cells, providing evidence that drugs used to treat diabetes could be used to reduce tumor growth in pancreatic and prostate cancers. Cancer cells require high amounts of the sugar glucose to survive and grow, and long-standing research has established passive glucose transporters, […]

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Nanoparticles Shut Down Cancer Growth

July 3, 2015

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Nanoparticles Shut Down Cancer Growth

Using nanoparticles to deliver a nucleic acid (siRNA) into tumor cells in mouse models, scientists from UCLA and City of Hope have become the first to inhibit the mechanism that drives cancer growth. When scientists develop cancer therapies, they target the features that make the disease deadly: tumor growth, metastasis, recurrence and drug resistance. In […]

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Yale Study Reveals Why BRCA Gene Resists Cancer Treatment

July 3, 2015

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New Discovery Reveals Why BRCA Gene Resists Cancer Treatment

A newly published study from Yale University reveals how biochemists might be able to decrease drug resistance to existing therapies that target ovarian and breast cancer. Yale University researchers have discovered why a key molecular assistant is crucial to the function of the BRCA2 gene, which in some mutant forms can lead to ovarian and […]

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A Link between Citrus Consumption and Malignant Melanoma?

July 2, 2015

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Citrus Consumption Increases the Risk of Cutaneous Malignant Melanoma

A new study from Brown University reveals that white people who consumed a lot of grapefruits or orange juice had a small but significantly higher 25-year risk of malignant melanoma. Providence, Rhode Island (Brown University) — Physicians have known for a while that compounds called psoralens make skin more sensitive to light exposure. Psoralens are […]

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Everyday Chemicals in Our Environment Cause Cancer When Combined

June 22, 2015

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Everyday Chemicals in Our Environment Cause Cancer When Combined

According to new research from a global taskforce, fifty chemicals the public are exposed to on a daily basis have been shown to trigger cancer when combined. A global taskforce of 174 scientists from leading research centres across 28 countries studied the link between mixtures of commonly encountered chemicals and the development of cancer. The […]

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Cavity Shaving Reduces the Risk of a Second Mastectomy

June 1, 2015

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Cavity Shaving Reduces Risk of Double Mastectomy

A newly published study reveals that cavity shaving halved the rates of positive margins and reexcision among patients with partial mastectomy. Removing more tissue during a partial mastectomy could spare thousands of breast cancer patients a second surgery, according to a Yale Cancer Center study. The findings were published online May 30 in the New […]

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Engineers Develop Probiotics That Can Detect Tumors

May 28, 2015

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Engineered Probiotics Can Detect Tumors in the Liver

By using probiotics, a team of engineers has devised a new way to detect cancer that has spread to the liver. Many types of cancer, including colon and pancreatic, tend to metastasize to the liver. The earlier doctors can find these tumors, the more likely that they can successfully treat them. “There are interventions, like […]

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Drug-Resistant EGFR May Have “Achilles Heel”

May 19, 2015

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Two Experimental Drugs Show Promise Against Drug-Resistant EGFR

Researchers from Yale University have discovered a key structural difference in the drug-resistant form of EGFR that could lead to new strategies to combat the disease. Drugs introduced more than a decade ago that target mutations in a protein known as the epidermal growth factor receptor (EGFR) held the promise of personalized treatments for a […]

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Targeting Brain Metastases with Stem Cell Therapy

April 27, 2015

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Targeting Breast to Brain Metastatic Tumor

Researchers have developed an in vivo imageable breast-to-brain metastasis mouse model. Using real time in vivo imaging and subsequent composite fluorescence imaging, they show a widespread distribution of micro- and macro-metastasis in different stages of metastatic progression. Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital (MGH) have developed an “imageable” mouse model of […]

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Implantable Device Allows Doctors to Identify the Best Chemotherapy Agents

April 24, 2015

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Implantable Device Tests Cancer Drugs in Patients

A team of engineers has developed a new implantable device that will allow doctors to test the effectiveness of cancer drugs and to identify drugs that work best for each patient prior to starting systemic administration of chemotherapy. More than 100 drugs have been approved to treat cancer, but predicting which ones will help a […]

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Ebola-Like Virus Safely Destroys Brain Tumors

April 17, 2015

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Virus Safely Destroys Brain Tumors

New research from Yale University details how scientists used a novel chimeric virus (VSV-LASV-GPC) containing genes from both Lassa and VSV to target and completely destroyed brain cancer without adverse actions within or outside the brain. Brain tumors are notoriously difficult for most drugs to reach, but Yale researchers have found a promising but unlikely […]

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Gold Nanoparticles Intensify Cancer-Killing Radiation

April 16, 2015

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Gold Enhances Radiation Effect on Cancer Cells

Using gold nanoparticles tethered to acid-seeking compounds called pHLIPs, a team of researchers has demonstrated a more precise method for targeting cancer cells with radiation. Providence, Rhode Island (Brown University) — Researchers from Brown University and the University of Rhode Island have demonstrated a promising new way to increase the effectiveness of radiation in killing […]

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New Approach Halts the Growth of a Very Aggressive Form of Melanoma

April 14, 2015

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Stimulating Major Branches of the Immune System Halts Tumor Growth More Effectively

By stimulating both major branches of the immune system, researchers from MIT were able to halt the growth of a very aggressive form of melanoma in mice. The human immune system is poised to spring into action at the first sign of a foreign invader, but it often fails to eliminate tumors that arise from […]

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