Cancer News

Immune Therapy Drug Prolongs Survival in Advanced Lung Cancer Patients

December 21, 2015

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Immune Therapy Drug Shows Promise in Fight Against Cancer

A newly published study involving patients with advanced non-small cell lung cancer resistant to chemotherapy has found a promising weapon in an immune therapy drug commonly used to treat other cancers. The findings were published December 19 in The Lancet and presented at the 2015 annual conference of the European Society for Medical Oncology in […]

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New Research Reveals How Cancer Cells Escape Blood Vessels

December 16, 2015

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Scientists Reveal How Cancer Cells Escape Blood Vessels

A newly published study from MIT and Massachusetts General Hospital reveals how cancer cells latch onto blood vessels and invade tissues to form new tumors — a finding that could help researchers develop drugs that inhibit this process and prevent cancers from metastasizing. Cancer cells circulating in the bloodstream can stick to blood vessel walls […]

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Yale Researchers Discover New Complexities Behind Drug Resistance

December 10, 2015

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New Study Probes Genes for Clues to Drug Resistance in Aggressive Breast Cancer

New research from Yale University probes genes for clues to drug resistance in aggressive breast cancer. By sifting through the 20,000 protein-encoding genes in the human genome, Yale researchers discovered new complexities behind drug resistance and identified patterns of mutations that could predict which therapies will benefit patients with aggressive breast cancer. The findings will […]

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Scientists Develop a New Way to Deliver MicroRNAs for Cancer Treatment

December 8, 2015

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Researchers Develop a New Way to Deliver MicroRNAs

By twisting RNA strands into a triple helix and embedding them in a biocompatible gel, researchers from MIT have developed a new way to shrink tumors in mice with an aggressive form of breast cancer. Twenty years ago, scientists discovered that short strands of RNA known as microRNA help cells to fine-tune their gene expression. […]

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New Strategy to Better Protect Cancer Patients from the Flu

December 7, 2015

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New Vaccine Better Protects Cancer Patients from Flu

Scientists from Yale University have developed a new vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented December 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida. Patients with cancers of the immune system, like multiple myeloma, […]

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MRI May Lead to Overdiagnosis of Cancer

December 2, 2015

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MRI May Lead to Overdiagnosis of Cancer for Older Women

New research from Yale University details how magnetic resonance imaging (MRI) for many women undergoing breast cancer surgery might identify health problems that would not otherwise impact patients — or lead to “overdiagnosis.” Published in the Journal of Clinical Oncology, the study examined whether preoperative MRI use would allow doctors to identify breast cancer in […]

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A New Paradigm for Cancer Research, One That Focuses on Improving Efficacy and Value

November 5, 2015

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A New Paradigm for Cancer Research

A newly published study from Yale University tackles the issue of value in cancer research, recommending a new paradigm for research that focuses on improving efficacy and value, as well as ensuring population health impact and generating new knowledge. The $100 billion federal government investment in the “War on Cancer,” has produced only relatively modest […]

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Rare ALK Genetic Mutation Extends Cancer Survival

October 15, 2015

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Rare Genetic Mutation Extends Cancer Survival

A new study from Yale University reveals that patients with the rare ALK mutation are living an average of four years, compared to typical patients that die of NSCLC within seven months. Most patients with non-small cell lung cancer (NSCLC) that has metastasized to the brain have a dire prognosis. But Yale researchers have identified […]

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Bioadhesive Nanoparticles Help Protect Your Skin From the Sun

September 28, 2015

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New Sunblock With Bioadhesive Nanoparticles

Dermatologists from Yale University have developed a new sunscreen made with bioadhesive nanoparticles that doesn’t penetrate the skin, eliminating serious health concerns associated with commercial sunscreens. Most commercial sunblocks are good at preventing sunburn, but they can go below the skin’s surface and enter the bloodstream. As a result, they pose possible hormonal side effects […]

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Brazilian Wasp Venom Kills Cancer Cells Without Harming Normal Cells

September 2, 2015

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Brazilian Wasp Venom Kills Cancer Cells Without Harming Normal Cells

A newly published study shows how Brazilian wasp venom selectively kills cancer cells without harming normal cells. The social wasp Polybia paulista protects itself against predators by producing venom known to contain a powerful cancer-fighting ingredient. A Biophysical Journal study published September 1 reveals exactly how the venom’s toxin–called MP1 (Polybia-MP1)–selectively kills cancer cells without […]

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New Model Captures Shape and Speed of Tumor Growth for the First Time

August 31, 2015

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Model Captures Shape and Speed of Tumor Growth for the First Time

Scientists at Harvard have developed the first model of solid tumor growth that reflects both shape and growth. They’re among the most powerful tools for demonstrating how cancer grows and spreads, but mathematical models of the disease have always faced an either/or problem. Models for capturing the spatial — or 3D — aspects of tumors […]

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Biologists Identify a New Approach to Cancer Immunotherapy

August 27, 2015

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A New Approach to Cancer Immunotherapy

Scientists from Yale University have identified a new way to boost immune response by metabolically “rewiring” immune cells. Inside a tumor, immune cells and cancer cells battle for survival. The advantage may go to the cells that metabolize the most glucose, say Yale researchers who have identified a new way to boost immune response by […]

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Researchers Reveal How Chronic Inflammation Can Lead to Cancer

August 11, 2015

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Researchers Discover How the Immune System Can Create Cancerous DNA Mutations

New research from MIT reveals how the immune system can create cancerous DNA mutations when fighting off infection. Chronic inflammation caused by disease or exposure to dangerous chemicals has long been linked to cancer, but exactly how this process takes place has remained unclear. Now, a precise mechanism by which chronic inflammation can lead to […]

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Take Time to Protect Your Kids’ Skin Now, It Could Prevent Cancer Later

July 31, 2015

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Protecting Kids’ Skin Now Can Prevent Cancer Later

Dermatologists stress that protecting your children from the sun now can help prevent cancer later. More parents appear to be vigilant about protecting their children from the sun’s harmful rays—at least at Yale Dermatology-Middlebury where Brittany Craiglow, M.D. practices. Many parents tell Dr. Craiglow they’ve started applying sunscreen so early in their children’s lives that […]

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Gene Therapy Gives Ovarian Cancer Patients Hope

July 28, 2015

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Gene Therapy Improves Survival Rates in Patients with Ovarian Cancer

A team of researchers from Harvard and Mass General Hospital has found a gene therapy that delivers a protein which suppresses the development of female reproductive organs, possibly improving the survival of patients with ovarian cancer that has recurred after chemotherapy. A gene therapy that delivers a protein that suppresses the development of female reproductive […]

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Pharmaceutical Firms “Underinvest” in Long-Term Cancer Research

July 28, 2015

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Do Firms Underinvest in Long-Term Cancer Research

A newly published study from MIT and the University of Chicago reveals that pharmaceutical firms “underinvest” in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research. Specifically, drugs to treat late-stage cancers are less costly to develop than drugs for earlier-stage cancers, partly because the […]

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Yale Scientists Reveal ‘Major Player’ in Skin Cancer Genes

July 27, 2015

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NF1 Identified as Major Player in Skin Caner Genes

Researchers from Yale University have confirmed that a gene known as NF1 is a “major player” in the development of skin cancer. A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed […]

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Yale Study Shows T Cell Lymphoma Caused by Gene Deletions

July 21, 2015

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Study Shows T Cell Lymphoma Caused by Unusually Large Number of Gene Deletions

A newly published study from Yale University shows that a deadly form of T cell lymphoma is caused by an unusually large number of gene deletions, making it distinct among cancers. Researchers conducted a genomic analysis of normal and cancer cells from patients with cutaneous T-cell lymphoma, a cancer of T-cells of the immune system […]

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