Disease News

New Study Shows Fructose Alters Brain Genes, Which Can Lead to Disease

April 25, 2016

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New Research Shows Fructose Alters Brain Genes, Can Lead to Disease

A new study by researchers at UCLA reveals that genes in the brain can be damaged by fructose, leading to diseases like diabetes, cardiovascular disease, Alzheimer’s disease and attention deficit hyperactivity disorder. A range of diseases — from diabetes to cardiovascular disease, and from Alzheimer’s disease to attention deficit hyperactivity disorder — are linked to […]

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New Findings Provide a Design for an HIV Vaccine Germline-Targeting Immunogen

March 28, 2016

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Scientists Announce New Anti-HIV Agent

A team of researchers has found HIV-1 broadly neutralizing antibody precursor B cells that are present in most people, and has described the design of an HIV vaccine germline-targeting immunogen capable of binding those B cells. Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and […]

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New Stem Cell Innovation Could Someday Help Treat Parkinson’s

March 17, 2016

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Stem Cell Innovation Could Treat Parkinson’s

A team of researchers from Rutgers and Stanford have created a new way to inject healthy human nerve cells into the brain that could someday help treat Parkinson’s disease and other devastating brain-related conditions that affect millions of people. The technology – a major innovation – involves converting adult tissue-derived stem cells into human neurons […]

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Yale Study Finds Racial Differences in Smoking Patterns

March 15, 2016

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Study Finds Differences in Smoking Habits between African Americans and Whites

A newly published study from Yale University reveals that differences in smoking habits between African Americans and whites may lead to a disparity in screening for lung cancer. The paper was published online March 15 in Nicotine & Tobacco Research. Cigarette smoking, the leading cause of preventable death in the United States, has been widely […]

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Scientists Reveal Amino Acids Supply Most Building Blocks for Tumor Cells

March 8, 2016

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Amino Acids Supply Most Building Blocks for Tumor Cells

New research shows that amino acids, not glucose, account for the majority of cell mass in proliferating mammalian cells. Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar. Scientists had believed […]

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Neuroscientists Discover a Behavioral State Gene That May be Linked to Autism

March 7, 2016

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Gene for Behavioral State May be Linked to Autism

In a newly published study, neuroscientists from MIT reeval a gene that plays a critical role in controlling the switch between alternative behavioral states – which for humans include hunger and fullness, or sleep and wakefulness. This gene, which the researchers dubbed vps-50, helps to regulate neuropeptides — tiny proteins that carry messages between neurons […]

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MIT Research Shows How Diet Influences Colon Cancer

March 2, 2016

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MIT Study Shows How Diet Influences Colon Cancer

New research from MIT reveals ties high-fat diet to changes in intestinal stem cells, helping to explain an increased cancer risk. Over the past decade, studies have found that obesity and eating a high-fat, high-calorie diet are significant risk factors for many types of cancer. Now, a new study from MIT reveals how a high-fat […]

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Yale Scientists Reveal Underlying Cause of Myeloma

February 11, 2016

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Yale Scientists Discover Underlying Cause of Myeloma

Scientists from the Yale Cancer Center have identified what causes a third of all myelomas, a type of cancer affecting plasma cells. The findings, published February 10 in the New England Journal of Medicine, could fundamentally change the way this cancer and others are treated. Multiple myeloma is a cancer involving the growth of plasma […]

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New Yale Study Pinpoints Key Protein in Severe Vascular Disease

February 9, 2016

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Key Protein in Severe Vascular Disease Revealed

New research from Yale University investigates factors that squeeze, or narrow, the aorta in a common vascular disease, revealing a target for potential new treatments. Individuals who suffer from supravalvular aortic stenosis, a condition characterized by narrowing of the aorta, have only one copy instead of the usual two copies of the gene encoding elastin. […]

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Biochemists Identify Another Piece of the Parkinson’s Disease Pathology Puzzle

January 28, 2016

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Researchers Identify another Piece in the Parkinson's Disease Pathology Puzzle

An international team has discovered that the LRRK2 kinase regulates cellular trafficking by deactivating Rab proteins. This finding illuminates a novel route for therapeutic development and may accelerate testing of LRRK2 inhibitors as a disease-modifying therapy for Parkinson’s, the second most common neurodegenerative disease. An international public-private research consortium has identified and validated a cellular […]

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Yale Researchers Identify Molecular Link between Obesity and Fatty Liver Disease

January 26, 2016

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New Link between Obesity and a Common Liver Disease Discovered

The high levels of obesity in the United States contribute to fatty liver disease, the most common form of liver disease. A newly published study from Yale University identifies molecular links between the two, and points to a possible therapy. Fatty liver disease — also known as nonalcoholic steatohepatitis or NASH — frequently progresses to […]

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Yale Examines How Bacteria Might Trigger and Treat Autoimmune Disease

January 11, 2016

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How Beneficial Bacteria Inside Our Bodies Might Trigger and Treat Autoimmune Disease

New research from Yale University is exploring how beneficial bacteria that live in the gut might trick the body into an autoimmune reaction known as antiphospholipid syndrome. Doctors often describe the body’s immune system in military terms. Physical barriers such as skin and mucus prevent invasion by disease-causing pathogens such as bacteria and viruses. If […]

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New Research Reveals How Cancer Cells Escape Blood Vessels

December 16, 2015

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Scientists Reveal How Cancer Cells Escape Blood Vessels

A newly published study from MIT and Massachusetts General Hospital reveals how cancer cells latch onto blood vessels and invade tissues to form new tumors — a finding that could help researchers develop drugs that inhibit this process and prevent cancers from metastasizing. Cancer cells circulating in the bloodstream can stick to blood vessel walls […]

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Scientists Develop “Kill Switches” for Engineered Bacteria

December 14, 2015

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Engineered Bacteria with Kill Switches

To prevent genetically modified bacteria from escaping into the wider environment, MIT researchers have developed safeguards in the form of two so-called “kill switches,” which they call “Deadman” and “Passcode.” These kill switches can cause synthetic bacteria to die without the presence of certain chemicals. Many research teams are developing genetically modified bacteria that could […]

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Yale Researchers Discover New Complexities Behind Drug Resistance

December 10, 2015

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New Study Probes Genes for Clues to Drug Resistance in Aggressive Breast Cancer

New research from Yale University probes genes for clues to drug resistance in aggressive breast cancer. By sifting through the 20,000 protein-encoding genes in the human genome, Yale researchers discovered new complexities behind drug resistance and identified patterns of mutations that could predict which therapies will benefit patients with aggressive breast cancer. The findings will […]

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Yale Study Shows Topical Ruxolitinib Grows Hair

December 9, 2015

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Topical Ruxolitinib Helps Teen Grow Hair

A new study from Yale University reveals that a topical formulation of an oral medication used to treat bone marrow diseases can be used to grow hair. A young woman who had no scalp or eyebrow hair for years now enjoys a full mane after using a novel cream devised by researchers at Yale School […]

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Scientists Develop a New Way to Deliver MicroRNAs for Cancer Treatment

December 8, 2015

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Researchers Develop a New Way to Deliver MicroRNAs

By twisting RNA strands into a triple helix and embedding them in a biocompatible gel, researchers from MIT have developed a new way to shrink tumors in mice with an aggressive form of breast cancer. Twenty years ago, scientists discovered that short strands of RNA known as microRNA help cells to fine-tune their gene expression. […]

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New Strategy to Better Protect Cancer Patients from the Flu

December 7, 2015

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New Vaccine Better Protects Cancer Patients from Flu

Scientists from Yale University have developed a new vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented December 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida. Patients with cancers of the immune system, like multiple myeloma, […]

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