Disease News

Yale Study Shows HIV Protease Inhibitors Also Offer Protection Against Malaria

December 19, 2014

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AIDS Drug Offers Protection Against Malaria

New research from Yale University shows that the use of protease inhibitor-based antiretroviral therapy for HIV is an effective measure for reducing malaria in HIV-infected children in most regions of sub-Saharan Africa. Children with HIV/AIDS in Africa are at a higher-than-average risk for another deadly disease: malaria. But a team of Yale School of Public […]

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Yale Study Shows Ebola Virus Spreads in Social Clusters

December 16, 2014

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Researchers Reveal Ebola Virus Spreads in Social Clusters

Using both genomic and epidemiological data from the current outbreak in Sierra Leone, researchers from Yale University discovered that the Ebola virus spreads in social clusters – a finding that has ramifications for case reporting and the public health. Prior studies of Ebola transmission were based on models that assumed the spread of infection occurred […]

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New Research Details Why Typhoid Toxin Targets Only Humans

December 8, 2014

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Study Reveals Why Typhoid Toxin Targets Only Humans

Scientists at Yale and UC San Diego have discovered why typhoid toxin targets only humans, revealing a single oxygen atom is the cause. The bacterium Salmonella Typhi causes typhoid fever in humans, but leaves other mammals unaffected. Researchers at University of California, San Diego and Yale University Schools of Medicine now offer one explanation — […]

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Researchers Uncover an Easily Detectable Precancerous State in Blood

December 4, 2014

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Researchers Uncovered a Detectable Precancerous State in Blood

Two newly published studies detail the discovery of a precancerous state found in blood, paving the way for research that focuses on detection and prevention of blood cancers. Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, the Harvard Stem Cell Institute (HSCI), and Harvard-affiliated hospitals have uncovered an easily detectable, “premalignant” […]

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Proper Copper Levels Essential to Spontaneous Neural Activity

December 2, 2014

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Proper Copper Levels Essential to Spontaneous Neural Activity

A new study from the Berkeley Lab reveals that proper copper levels are essential to the health of a brain at rest and suggests that mismanagement of copper in the brain linked to Alzheimer’s and other neurological disorders can also contribute to misregulation of signaling in cell−to-cell communications. In recent years it has been established […]

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Discovery Hints at New Strategy for Fighting HIV

November 19, 2014

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New Strategy for Fighting HIV

Researchers from Yale University have discovered an immune system reaction that may open a new avenue in the fight against HIV. The discovery of the innate immunity system’s role in mobilizing the body’s defenses against invading microorganisms has been long studied at Yale. Now in the November 17 issue of the journal Nature Immunology, Yale […]

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Yale Researchers Develop Method to Attack Cancer at Its Source

November 18, 2014

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Yale Develops Method to Attack Cancer at Its Genetic Source

A team of researchers at Yale University has developed a therapeutic molecule that both targets the acidic microenvironments of tumors and penetrates cells to deliver a therapeutic cargo. MicroRNAs may be tiny — as few as 20 genetic letters, compared to 3 billion in the DNA of a human — but they play a major […]

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New Algorithm Predicts the Evolution of Viruses

November 12, 2014

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Algorithm Can Predict the Evolution of Viruses

Using the branches of a genealogical tree as reference, a team of scientists has developed an algorithm that can predict the evolution of asexual organisms such as viruses or cancer cells. For a long time, prognoses forecasting the evolutionary future of organisms were considered mere speculation. Together with researchers from Cambridge and Santa Barbara, USA, […]

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New Gene-Editing Technique Could Prove to be an Effective Technique for Blocking HIV

November 11, 2014

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Researchers Genetically Edit Human Blood Stem Cells

Using CRISPR Cas technology, researchers genetically ‘edit’ human blood stem cells to create what could prove to be an effective technique for blocking HIV. Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General (MGH) and Boston Children’s hospitals (BCH) for the first time have used a relatively new gene-editing technique to create what could prove […]

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Muscle Mass and Chronic Kidney Disease

November 10, 2014

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Muscle Mass is Not an Accurate a Predictor of Chronic Kidney Disease

A newly published study from Yale University reveals that muscle mass is not as accurate a predictor of chronic kidney disease outcomes as previously thought. In a study published online by the Clinical Journal of the American Society of Nephrology, researchers looked at data from 3,604 patients with chronic kidney disease. They checked for an […]

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A Direct Link between Climate Change and the Emergence of Infectious Diseases

November 5, 2014

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Researchers Discover Connection between Climate and Emerging Diseases

A team of researchers has established a direct link between climate change and the emergence of infectious diseases, showing a correlation between epidemic peaks and rainy periods for Buruli ulcer observed over a 40-year period in French Guyana. New diseases Climate change may affect human health directly or indirectly. In addition to increased threats of […]

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Molecular Map Pinpoints Genetic Variants of Autoimmune Diseases

October 30, 2014

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New Molecular Map Reveals Genetic Origins of Autoimmune Diseases

Researchers have developed a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, providing new insight into the cause of multiple sclerosis and other autoimmune diseases. Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and […]

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Targeted Isolation May Be the Most Effective Way to Reduce Transmission of Ebola

October 28, 2014

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Isolation May Be the Most Effective Way to Reduce Transmission of Ebola

New research led by the Yale School of Public Health shows that isolating 75% of infected individuals in critical condition within four days of symptom onset has a high chance of eliminating the spread of Ebola. Isolating the most severely ill Ebola patients before the fifth day of their illness may be the most effective […]

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Yale Scientists Reveal Ebola Epidemic in Africa Poised to Explode

October 24, 2014

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Yale Study Shows Ebola Epidemic in Africa Poised to Explode

An international team of scientists has developed a new mathematical transmission model of the Ebola disease and applied it to Liberia’s most populous county, revealing that tens of thousands of new Ebola cases and deaths are likely by December 15 if the epidemic continues on its present course. The Ebola virus disease epidemic already devastating […]

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21-Day Quarantine Might Not Be Enough to Prevent the Spread of Ebola

October 16, 2014

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Study Questions 21 Day Quarantine For Ebola

A new study from Drexel University suggests that 21 days might not be enough to completely prevent spread of Ebola, revealing that there could be up to a 12 percent chance that someone could be infected even after the 21-day quarantine. As medical personnel and public health officials are responding to the first reported cases […]

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