Disease News

Yale Scientists Discover a New Therapy for a Chronic Brain Disease

August 23, 2016

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Yale Biologists Uncover Marker for a Chronic Brain Disease

Yale scientists have discovered a new and effective therapy for cerebral cavernous malformations. A team of researchers led by Yale professor of pathology Wang Min have pinpointed a marker that contributes to a chronic condition affecting the brain. Known as cerebral cavernous malformations, the condition is characterized by a tangle of capillaries in the brain’s […]

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MIT Biological Engineers Program Human Cells to Store Complex Histories in Their DNA

August 22, 2016

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Recording Analog Memories in Human Cells

Newly published research details how biological engineers from MIT developed a way to record complex histories in the DNA of human cells, allowing them to retrieve “memories” of past events by sequencing the DNA. This analog memory storage system — the first that can record the duration and/or intensity of events in human cells — […]

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New Yale Research Reveals Insights into Alcoholic Liver Disease

August 11, 2016

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New Insights into Alcoholic Liver Disease

A team of researchers at the Yale School of Public Health has identified a novel mechanism that protects the liver against the accumulation of fats and may represent a promising new therapeutic approach for treating and/or preventing alcoholic liver disease (ALD) and other fatty liver diseases. Professor Vasilis Vasiliou, chair of the Department of Environmental […]

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Adhesive Patch Delivers Therapy to Tumor Sites

August 1, 2016

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New Device Delivers Therapy to Tumor Sites

A newly published study from MIT describes an adhesive patch that can stick to the tumor site, either before or after surgery, to deliver a triple-combination of drug, gene, and photo (light-based) therapy. Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in […]

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Yale Scientists Recode Organisms to Resist Viral Contamination

July 18, 2016

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Scientists Recode Organisms to Resist Viral Contamination

Scientists from Yale University have discovered a novel way to combat viral contamination of bio-factories that produce a growing number of drugs, chemicals, and fuels. The new method involves recoding organisms to stop horizontal transfer of genes — which viruses use to infect and hijack cellular machinery to reproduce. The study is published in the […]

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New Study Improves Our Understanding of Intercellular Communication

July 6, 2016

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Biologists Improve Our Understanding of Intercellular Communication

New research reveals how cells can pack and release active ephrins and Eph receptors through extracellular vesicles, improving our understanding of intercellular communication and paving the way for new therapeutic strategies. Eph receptors and their partner proteins, the ephrins, are vital for intercellular communication. In the developing brain, they guide young neurons to the right […]

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Engineers Design Programmable RNA Vaccines That Protext Against Ebola and H1N1 Influenza

July 5, 2016

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MIT Engineers Design Programmable RNA Vaccines

A newly published study details how engineers developed programmable RNA vaccines that work against Ebola, H1N1 influenza, and a common parasites in mice. MIT engineers have developed a new type of easily customizable vaccine that can be manufactured in one week, allowing it to be rapidly deployed in response to disease outbreaks. So far, they […]

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Yale Study Shows Surprising Link Between Constipation and Herpes Infection

June 9, 2016

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Surprising Link Between Constipation and Herpes Infection

New research from Yale University shows a surprising link between constipation and herpes infection. The new research, published June 8 in Cell Host & Microbe, advances the science on herpes, and could help patients with chronic gastrointestinal diseases with no clear cause. Individuals with herpes have reported seemingly unrelated symptoms such as constipation and urinary […]

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New Combination Therapy Cures Tick-Borne Illness in Mice

June 6, 2016

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New Therapy Cures Tick-Borne Illness in Mice

Yale researchers have developed a new therapy that cures the emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease. This “radical” therapy not only clears the infection but also prevents the recurrence that often occurs with existing treatments. The study was published online June 6 in […]

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Study Shows MRI Detects Early Signs of Schizophrenia

June 3, 2016

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MRI Detects Early Signs of Schizophrenia

A new study from Yale University shows that an MRI can detect early signs of schizophrenia in a rodent model. Patients with schizophrenia often exhibit early signs of behavioral abnormalities. However, changes in the brain underlying these behavioral signs have not been identified. Applying magnetic resonance scanning techniques that are used in humans, Yale researchers […]

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Yale Researchers Reveal How Antibodies Access Neurons to Fight Infection

May 23, 2016

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Yale Researchers Show How Antibodies Access Neurons to Fight Infection

New research from Yale University reveals how antibodies enter the nervous system to control viral infections. The findings may have implications for the prevention and treatment of a range of conditions, including herpes and Guillain-Barre syndrome, which has been linked to the Zika virus. Many viruses — such as West Nile, Zika, and the herpes […]

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New Evidence That Diet and Gut Microbes Can Influence Brain Inflammation

May 16, 2016

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Researchers Find Evidence That Diet and Gut Microbes Can Influence Brain Inflammation

A newly discovered link between deficits in gut flora and brain inflammation may lead researchers to learn more about its impact on multiple sclerosis. A team of investigators at Harvard-affiliated Brigham and Women’s Hospital (BWH) has found evidence that suggests that bacteria living in the gut may remotely influence the activity of cells in the […]

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New Approach Identifies Genetic Markers Linked to Complex Diseases

May 10, 2016

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Study Identifies New Gene Variants for Treating Arrhythmia

Researchers from MIT have developed a new approach that identifies genetic markers linked to complex diseases. Many diseases, such as cancer, diabetes, and schizophrenia, tend to be passed down through families. After researchers sequenced the human genome about 15 years ago, they had high hopes that this trove of information would reveal the genes that […]

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Yale Researchers Identify a Genetic Mutation Linked to Acne

May 5, 2016

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Yale Study Zeroes in on Mutation Linked to Zits

New research from Yale University has identified a genetic mutation responsible for the defects that give rise to mild and severe acne, possibly revealing new targets for acne treatment. In the study, the Yale-led team took blood and tissue samples from three individuals with a rare form of acne known as nevus comedonicus. By sequencing […]

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New Study Shows Fructose Alters Brain Genes, Which Can Lead to Disease

April 25, 2016

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New Research Shows Fructose Alters Brain Genes, Can Lead to Disease

A new study by researchers at UCLA reveals that genes in the brain can be damaged by fructose, leading to diseases like diabetes, cardiovascular disease, Alzheimer’s disease and attention deficit hyperactivity disorder. A range of diseases — from diabetes to cardiovascular disease, and from Alzheimer’s disease to attention deficit hyperactivity disorder — are linked to […]

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New Findings Provide a Design for an HIV Vaccine Germline-Targeting Immunogen

March 28, 2016

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Scientists Announce New Anti-HIV Agent

A team of researchers has found HIV-1 broadly neutralizing antibody precursor B cells that are present in most people, and has described the design of an HIV vaccine germline-targeting immunogen capable of binding those B cells. Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and […]

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New Stem Cell Innovation Could Someday Help Treat Parkinson’s

March 17, 2016

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Stem Cell Innovation Could Treat Parkinson’s

A team of researchers from Rutgers and Stanford have created a new way to inject healthy human nerve cells into the brain that could someday help treat Parkinson’s disease and other devastating brain-related conditions that affect millions of people. The technology – a major innovation – involves converting adult tissue-derived stem cells into human neurons […]

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Yale Study Finds Racial Differences in Smoking Patterns

March 15, 2016

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Study Finds Differences in Smoking Habits between African Americans and Whites

A newly published study from Yale University reveals that differences in smoking habits between African Americans and whites may lead to a disparity in screening for lung cancer. The paper was published online March 15 in Nicotine & Tobacco Research. Cigarette smoking, the leading cause of preventable death in the United States, has been widely […]

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