Medicine News

Reg3beta Regulates Healing Process after Myocardial Infarction

March 25, 2015

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Reg3beta Controls Healing Process in the Heart

A new study from the Max Planck Institute details how Reg3beta controls the wound-healing process in the myocardium by attracting immune cells to the infarct tissue. In the wake of a myocardial infarction, parts of the myocardium die and are replaced by scar tissue. The formation and stability of scar tissue is key to the […]

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Deceased Donor Kidneys with Acute Injury Can Be Used for Transplants

March 13, 2015

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Study Reveals Injured Kidneys Can be Used for Transplants

New research from Yale University shows that kidneys from deceased donors that have acute injuries can be successfully used for transplants, instead of being discarded. The study finds that such kidneys may be more viable than previously thought, and should be considered to meet the growing demand for organ transplants. The study was published March […]

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Yale Develops a Faster and Less Expensive Way to Analyze Gene Activity

March 4, 2015

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A Faster and Less Expensive Way to Analyze Gene Activity

A newly published study details a method called modular, early-tagged amplification (META) RNA profiling that can quantify a broad panel of microRNAs or mRNAs simultaneously across many samples and requires far less sequence depth than existing digital profiling technologies. A team of Yale researchers has developed a simple method that could significantly reduce the time […]

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Antifreeze Protein Fights Frostbite in Mice

February 26, 2015

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Antifreeze Protein Fights Frostbite

A new study from Yale University shows that a protein that protects ticks from freezing temperatures also prevents frostbite when introduced in mice. This is the first study to demonstrate the protein’s ability to boost frostbite resistance in an adult mammal. The research was published February 25 in the journal PLOS ONE. Several animal species, […]

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New Anti-HIV Candidate Blocks Every Strain of HIV-1, HIV-2 and SIV

February 18, 2015

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Scientists Announce New Anti-HIV Agent

In a new study, researchers show that a new drug candidate blocks every strain of HIV-1, HIV-2 and SIV that has been isolated from humans or rhesus macaques, including the hardest-to-stop variants. Jupiter, Florida – February 18, 2015 – In a remarkable new advance against the virus that causes AIDS, scientists from the Jupiter, Florida […]

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Yale Study Reveals Anti-Inflammatory Mechanism of Dieting and Fasting

February 17, 2015

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Researchers Reveal Anti-Inflammatory Mechanism of Dieting and Fasting

New research from Yale University shows that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease. In their study, published in the February 16 online issue of Nature Medicine, the researchers described […]

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Engineered Insulin Stays in Bloodstream, Offers Better Diabetes Control

February 10, 2015

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Engineered Insulin Offers Better Diabetes Control

Engineers from MIT have developed insulin that can circulate in the bloodstream for hours, responding rapidly to changes in blood-sugar levels. For patients with diabetes, insulin is critical to maintaining good health and normal blood-sugar levels. However, it’s not an ideal solution because it can be difficult for patients to determine exactly how much insulin […]

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Scientists Identify Link between Inflammation and Type 2 Diabetes

February 6, 2015

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Researchers Identify Link between Inflammation and Type 2 Diabetes

A newly published study led by Yale University reveals the molecular mechanism by which insulin normally inhibits production of glucose by the liver and why this process stops working in patients with type 2 diabetes, leading to hyperglycemia. The findings are published February 5 in the journal Cell. “In the study, we set out to […]

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Potential Over-Treatment of Diabetes in Older Adults

January 14, 2015

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Study Shows Risk of Over Treatment in Older Diabetes Patients

New research from the Yale School of Medicine shows that aggressively controlling blood sugar with insulin and sulfonylurea drugs in older patients with multiple medical conditions could lead to over-treatment and hypoglycemia (low blood sugar). Published in the January 12 issue of JAMA Internal Medicine, the study found that many older diabetes patients received aggressive […]

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Researchers May Have Pinpointed a Strategy for Eliminating Latent HIV

January 8, 2015

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Study Shows Broad Immune Response May be Needed to Destroy Latent HIV

A newly published study shows promise as the future direction for the development of a therapeutic vaccine to clear HIV. A major barrier to finding a cure for HIV/AIDS is the presence of latent HIV in the cells of chronically infected individuals. But a team of Yale and Johns Hopkins researchers may have pinpointed a […]

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Yale Study Shows Metformin May be Safe for Patients with Kidney Disease

December 29, 2014

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Diabetes Drug May be Safe for Patients with Kidney Disease

A newly published study from Yale University reveals that metformin (the most popular treatment for type 2 diabetes) may be safer for patients with mild to moderate kidney disease than guidelines suggest. The new study is published by Yale investigators in the Journal of the American Medical Association (JAMA). For 20 years, metformin has been […]

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New Research Shows Molecular Decoys Help Overcome Drug Resistance

December 12, 2014

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Research Shows Molecular Decoys Help Overcome Drug Resistance

By using molecular fragments administered alongside antimicrobial agents, researchers at Brown University have shown that the efflux pumps are kept busy pumping out the fragments while the antimicrobial agents are able to stay inside the cell. Providence, Rhode Island – Brown University – Harmful bacteria have evolved some ingenious mechanisms to resist antibiotics. One of […]

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Researchers Uncover an Easily Detectable Precancerous State in Blood

December 4, 2014

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Researchers Uncovered a Detectable Precancerous State in Blood

Two newly published studies detail the discovery of a precancerous state found in blood, paving the way for research that focuses on detection and prevention of blood cancers. Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, the Harvard Stem Cell Institute (HSCI), and Harvard-affiliated hospitals have uncovered an easily detectable, “premalignant” […]

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New Algorithm Analyzes Carbon Dioxide to Help Determine How to Treat Patients

November 6, 2014

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New Algorithm Can Help Determine How to Treat Patients

Researchers from MIT, Harvard Medical School and the Einstein Medical Center in Philadelphia have developed a new algorithm that can, with high accuracy, determine whether a patient is suffering from emphysema or heart failure based on the concentration of carbon dioxide in a patient’s exhalations. Paramedics respond to a 911 call to find an elderly […]

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Engineered Liposomes: A Possible Alternative to Antibiotics

November 5, 2014

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Scientists Develop a Possible Alternative to Antibiotics

By engineering artificial nanoparticles made of lipids, scientists have developed a treatment for bacterial infections without using antibiotics. Scientists from the University of Bern have developed a novel substance for the treatment of severe bacterial infections without antibiotics, which would prevent the development of antibiotic resistance. Ever since the development of penicillin almost 90 years […]

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Targeted Chemotherapy Delivery Could Kill Tumor Cells More Effectively

October 28, 2014

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New Approach Could Kill Tumor Cells in the Brain More Effectively

New research shows that delivering chemotherapy directly into the brain cavity may kill tumor cells in the brain more effectively and avoid side effects. Every year, about 100,000 Americans are diagnosed with brain tumors that have spread from elsewhere in the body. These tumors, known as metastases, are usually treated with surgery followed by chemotherapy, […]

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Antifreeze Protein in Ticks Could Lead to New Antibiotics for Humans

October 17, 2014

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Tick Protein Inspires New Class of Antibiotics

Scientists from Yale University have discovered that an antifreeze protein in ticks that kicks in during winter can also fights infection, possibly leading to a new class of antibiotics for humans. A protein in ticks that protects them against the cold could inspire a new class of antibiotics for humans, according to a Yale University […]

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