Medicine News

Yale Researchers Discover New Cancer Cell Vulnerability

July 21, 2014

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New research from Yale University found that simultaneous inhibition of both telomerase and p21 inhibited tumor growth in mice. Yale School of Medicine and Yale Cancer Center researchers have uncovered a genetic vulnerability of cancer cells that express telomerase — an enzyme that drives their unchecked growth — and showed that telomerase-expressing cells depend upon […]

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Newly Designed Nanoparticles Can Deliver Three Cancer Drugs at a Time

April 15, 2014

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In a newly published study, MIT chemists detail how they designed nanoparticles that can deliver three cancer drugs at a time. Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but […]

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Researchers Uncover Mode of Action of New Multiple Sclerosis Drug

April 7, 2014

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Scientists from the Max Planck Institute and the University of Lübeck have uncovered the mode of action for dimethyl fumarate, a drug that was recently approved in Europe as a basic therapy for multiple sclerosis. Just a few short weeks ago, dimethyl fumarate was approved in Europe as a basic therapy for multiple sclerosis. Although […]

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New Retinal Implant Technology Expected to Help Restore Sight

November 6, 2013

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In an effort to improve retinal implant technology, researchers have developed a new method that uses microsecond pulses, on-chip counter-electrodes, and controlled firing of electrodes to shape the electrical field, which could help people who have lost their sight see more than just light and vague shapes. Researchers at the University of Arizona and University […]

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Stanford Scientists Are Developing a Mini-Microscope to Detect Cancer Cells

October 1, 2013

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Stanford scientists are developing a mini-microscope to noninvasively detect circulating tumor cells, allowing for earlier interventions. One of the cruelest truths about cancer is that even after you beat the disease, it can still come back to kill you. A tumor growing in the prostate gland, breast, or any other organ can shed cancerous cells […]

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Microbicide Tricks HIV into “Popping” Itself into Oblivion

September 20, 2013

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Researchers from Drexel University have developed a microbicide that can trick HIV into “popping” itself into oblivion, destroying the virus without harming healthy cells. Pinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been a challenge for scientists and physicians, because the virus […]

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Genomic Test Accurately Distinguishes between Viral and Bacterial Infections

September 19, 2013

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A new genomic test developed by researchers at Duke University School of Medicine can accurately sort between viral and bacterial infections, possibly helping to limit the overuse of antibiotics and the emergence of bacterial resistance. A blood test developed by researchers at Duke Medicine showed more than 90-percent accuracy in distinguishing between viral and bacterial […]

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Therapeutic Cancer Vaccine Begins Human Clinical Trials

September 6, 2013

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A Phase I clinical trial of an implantable vaccine to treat melanoma has begun. A cross-disciplinary team of scientists, engineers, and clinicians announced today that they have begun a Phase I clinical trial of an implantable vaccine to treat melanoma, the most lethal form of skin cancer. The effort is the fruit of a new […]

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Experimental Compound Improves Learning and Memory in Mice with Down Syndrome

September 5, 2013

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In a newly published study, scientists detail the development of an experimental compound that reverses Down syndrome-like learning deficits in mice. Researchers at Johns Hopkins and the National Institutes of Health have identified a compound that dramatically bolsters learning and memory when given to mice with a Down syndrome-like condition on the day of birth. […]

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Drug Candidate SR9009 Increases Exercise Endurance

August 21, 2013

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A new drug candidate, SR9009, has been shown to significantly increase exercise endurance in animal models. Researchers believe these findings may lead to better treatments for people suffering from conditions that acutely limit exercise tolerance. An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The […]

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Newly Discovered Small Molecule Inhibitor Boosts Insulin Signaling

August 14, 2013

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Harvard Medical School researchers have uncovered a new pathway in insulin resistance and show that a newly discovered small-molecule inhibitor can interrupt this pathway and increase insulin signaling. Insulin resistance unleashes a vicious cycle in Type 2 diabetes whereby excess blood sugar induces the release of yet more insulin by the pancreas. A primary goal […]

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Deltarasin Blocks Oncogenic Protein KRAS, Opens Up New Approaches to Cancer Therapy

August 8, 2013

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Scientists at the Max Planck Institute have discovered how Deltarasin prevents the transport of the oncogenic protein KRAS to the cell membrane, opening up new approaches to cancer therapy treatment. One of the major goals in the development of anti-cancer treatments is to find an inhibitor effective against the oncogenic protein known as KRAS. Despite […]

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