Medicine News

Yale Study Shows One in Four Hepatitis C Patients Denied Initial Drug Therapy

August 28, 2015

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Yale Study Shows One in Four Hepatitis C Patients Denied Initial Care

A new study from the Yale School of Medicine found that nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection. The finding, published August 27 in PLOS ONE, identifies a new barrier to caring for patients with […]

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P2Y2 Receptor Helps Control Blood Pressure

August 4, 2015

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Researchers Discover New Receptor for Controlling Blood Pressure

New research from the Max Planck Institute shows that the P2Y2 receptor in blood vessel cells is a key element in the chain of blood pressure regulation. High blood pressure is a primary risk factor in the development of many cardiovascular diseases. Researchers at the Max Planck Institute for Heart and Lung Research in Bad […]

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Feeding Behavior in Worms May Help Shed Light on Human Heart Function

August 1, 2015

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Feeding Behavior in Worms Could Shed Light on Human Heart Function

In a new study from MIT researchers reveal that a simple roundworm has the ability to spit out potentially deadly substances — a finding that could have surprising implications for human heart research. Tasting and spitting out toxic food is a survival trait shared by many complex organisms. To feed, the worm uses its pharynx, […]

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Gene Therapy Gives Ovarian Cancer Patients Hope

July 28, 2015

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Gene Therapy Improves Survival Rates in Patients with Ovarian Cancer

A team of researchers from Harvard and Mass General Hospital has found a gene therapy that delivers a protein which suppresses the development of female reproductive organs, possibly improving the survival of patients with ovarian cancer that has recurred after chemotherapy. A gene therapy that delivers a protein that suppresses the development of female reproductive […]

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Pharmaceutical Firms “Underinvest” in Long-Term Cancer Research

July 28, 2015

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Do Firms Underinvest in Long-Term Cancer Research

A newly published study from MIT and the University of Chicago reveals that pharmaceutical firms “underinvest” in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research. Specifically, drugs to treat late-stage cancers are less costly to develop than drugs for earlier-stage cancers, partly because the […]

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Researchers Develop a New Device for Studying Changes in T Cells

July 22, 2015

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New Device Tracks Changes in T Cells

Scientists at the Yale School of Engineering and Applied Sciences have developed a passive-flow microfluidic device for imaging latent HIV activation dynamics in single T cells. While studying latent HIV cells, researchers in the laboratory of Prof. Kathryn Miller-Jensen have developed a device that could make it a lot easier to track changes in cells […]

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Yale Researchers Successfully Treat Eczema with Rheumatoid Arthritis Drug

July 20, 2015

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Yale Researchers Successfully Treat Eczema with Arthritis Drug

A team of scientists at Yale University used a rheumatoid arthritis drug to successfully treated patients with moderate to severe eczema. The same rheumatoid arthritis drug (tofacitinib citrate) has recently shown to reverse two other disfiguring skin conditions, vitiligo and alopecia areata. The research findings are published early online in the Journal of the American […]

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New Stem Cell Study May Lead to New Drug Targets for Autism Treatment

July 17, 2015

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New Stem Cell Study Could Help Predict ASD

Using stem cells generated from skin biopsies of four patients with ASD, researchers from Yale University grew the stem cells into three-dimensional simulated miniature human brains to compare gene expression between the patients and their family members. A larger head size — or macrocephaly — is seen in many children with severe autism spectrum disorder […]

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Diabetes Medication Could Be Used to Reduce Tumor Growth

July 14, 2015

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Diabetes Medicine Could Reduce Tumor Growth

Researchers from UCLA have identified a new mechanism that delivers glucose to cancer cells, providing evidence that drugs used to treat diabetes could be used to reduce tumor growth in pancreatic and prostate cancers. Cancer cells require high amounts of the sugar glucose to survive and grow, and long-standing research has established passive glucose transporters, […]

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Pulsed Electrical Discharge Producing Nitric Oxide, Can Save Young Lives

July 8, 2015

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New Invention Can Save Young Lives

Researchers from Harvard Medical School and Massachusetts General Hospital have developed a new device that produces nitric oxide from an electric spark, making treatment affordable and easy for those with persistent pulmonary hypertension. Under certain conditions, this device could replace the current technology that is both costly and cumbersome. Treatment with inhaled nitric oxide (NO) […]

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Cancer Drug Prolongs the Life of Fruit Flies, Could Do the Same for Humans

June 30, 2015

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Cancer Drug Prolongs Life

Using a cancer drug called Trametinib, biologists have extended the life expectancy in fruit flies by around twelve percent. The researchers believe that the substance could be used to develop future anti-aging drugs to extend life expectancy in humans. Humans, yeasts and fruit flies began to evolve separately millions of years ago. Nevertheless, the cellular […]

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Overuse of Medical Services Increases Healthcare Costs

June 29, 2015

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Is Healthcare Taking Advantage of You

Are doctors running the bill up on you? A new study from Yale University shows that a key factor to increased healthcare costs is overuse of medical services. As the cost of health care in the United States continues to rise, a new study by Yale researchers offers insight into a key factor influencing increased […]

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Study Shows Arthritis Drug Restores Skin Color for Vitiligo Patients

June 26, 2015

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Arthritis Drug Restores Skin Color in Vitiligo Patients

New research from Yale University demonstrates the effectiveness of tofacitinib for treating vitiligo. After five months of treatment, the white spots on the patients face and hands were nearly gone and tofacitinib caused no adverse side effects during the course of treatment. shows that Within two months of treatment, the patient experienced partial repigmentation on […]

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New Drug to Quiet Brain, Relieving Epilepsy and Tinnitus

June 24, 2015

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New Drug to Quiet Brain, Relieve Epilepsy and Tinnitus

Overly excited nerve cells cause problems like epilepsy and tinnitus. A new drug that selectively affects potassium channels promises relief with fewer side effects. A new drug may treat epilepsy and prevent tinnitus by selectively affecting potassium channels in the brain, UConn neurophysiologist Anastasios Tzingounis and colleagues report in the 10 June Journal of Neuroscience. […]

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Breakthrough Technique Accurately Detects the ‘Handedness’ of Molecules

June 24, 2015

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Breakthrough Technique Accurately Detects the Handedness of Molecules

A new technique that can determine whether a molecule is present in a left- or right-handed form may have a multitude of practical applications, potentially leading to new and improved drugs, diagnosis methods, and pesticides. Scientists have demonstrated for the first time the ability to rapidly, reliably and simultaneously identify the ‘handedness’ of different molecules […]

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Researchers Increase Energy-Burning Brown Fat Cells

June 17, 2015

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New Discovery Could Help Researchers Increase Good Fat in Patients

A team of researchers has discovered a way to increase energy-burning human brown fat cells and to make them more active, a discovery that could have therapeutic potential for diabetes, obesity, and other metabolic diseases. Harvard Stem Cell Institute (HSCI) scientists have found a way to both make more energy-burning human brown fat cells and […]

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PROTACs: A New Type of Drug That Can Target All Disease-Causing Proteins

June 11, 2015

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New Type of Drug Can Target All Disease-Causing Proteins

A newly published study from Yale University details the discovery of a new type of drug, called Proteolysis Targeting Chimeras (PROTACs), which can target all disease-causing proteins. Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but […]

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New Mathematical Model Helps Predicts Optimal Use of Antibiotics

May 15, 2015

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Mathematical Model Predicts Optimal Use of Antibiotics

Researchers at the Yale School of Public Health have developed a new mathematical model to help predict the optimal dosing of antibiotics. Although antibiotics were first introduced more than 70 years ago, substantial uncertainty remains about how the drugs should be used by patients to ensure recovery, while minimizing toxic side effects and the risk […]

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