Medicine News

Yale Researchers Show Parents Underestimate Their Children’s Weight

March 24, 2016

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Yale Study Shows Parents Underestimate Their Children's Weight

A new study form Yale University details how some parents underestimate their children’s weight, a misperception with important implications for clinical prevention and treatment of childhood obesity. Janet A. Lydecker, PhD, postdoctoral associate in psychiatry, and Carlos M. Grilo, PhD, professor of psychiatry and of psychology, and director of the Yale Program for Obesity Weight […]

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Yale Study Shows Key Protein In Pancreatic Cancer Growth May Also Be Its Undoing

March 14, 2016

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A New Target for Attacking Pancreatic Cancer

In a newly published study, Yale scientists reveal that the overexpression of a protein called renalase in pancreatic cancer plays a critical role in spurring the cancer’s growth while also providing a possible new target for attacking the tumors it helps develop. Pancreatic cancer is one of the deadliest cancers, causing about 40,000 deaths annually […]

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New Yale Study Pinpoints Key Protein in Severe Vascular Disease

February 9, 2016

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Key Protein in Severe Vascular Disease Revealed

New research from Yale University investigates factors that squeeze, or narrow, the aorta in a common vascular disease, revealing a target for potential new treatments. Individuals who suffer from supravalvular aortic stenosis, a condition characterized by narrowing of the aorta, have only one copy instead of the usual two copies of the gene encoding elastin. […]

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Life-Extending Hormone FGF21 Also Protects Against the Loss of Immune Function

January 14, 2016

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FGF21 Hormone Protests Against the Loss of Immune Function

New research from Yale University shows that the hormone FGF21, which extends lifespan in mice by 40%, protects against the loss of immune function that comes with age. Published online in the Proceedings of the National Academy of Sciences on January 11, the study’s findings have future implications for improving immune function in the elderly, […]

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Immune Therapy Drug Prolongs Survival in Advanced Lung Cancer Patients

December 21, 2015

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Immune Therapy Drug Shows Promise in Fight Against Cancer

A newly published study involving patients with advanced non-small cell lung cancer resistant to chemotherapy has found a promising weapon in an immune therapy drug commonly used to treat other cancers. The findings were published December 19 in The Lancet and presented at the 2015 annual conference of the European Society for Medical Oncology in […]

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Hospital Price Study Reveals ‘Mind-Boggling’ Variation Across USA

December 16, 2015

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Hospital Prices Show Mind-Boggling Variation Across USA

A new study from Yale University economists reveals that the prices hospitals negotiate with health insurance companies vary enormously within and across geographic regions in the United States. For example, the study shows that in 2011 hospital prices for lower-limb MRIs were 12 times higher in the most expensive region of the United States (Bronx, […]

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Yale Study Shows Topical Ruxolitinib Grows Hair

December 9, 2015

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Topical Ruxolitinib Helps Teen Grow Hair

A new study from Yale University reveals that a topical formulation of an oral medication used to treat bone marrow diseases can be used to grow hair. A young woman who had no scalp or eyebrow hair for years now enjoys a full mane after using a novel cream devised by researchers at Yale School […]

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Scientists Develop a New Way to Deliver MicroRNAs for Cancer Treatment

December 8, 2015

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Researchers Develop a New Way to Deliver MicroRNAs

By twisting RNA strands into a triple helix and embedding them in a biocompatible gel, researchers from MIT have developed a new way to shrink tumors in mice with an aggressive form of breast cancer. Twenty years ago, scientists discovered that short strands of RNA known as microRNA help cells to fine-tune their gene expression. […]

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New Strategy to Better Protect Cancer Patients from the Flu

December 7, 2015

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New Vaccine Better Protects Cancer Patients from Flu

Scientists from Yale University have developed a new vaccine strategy that reduces the risk of flu infections in cancer patients at highest risk for influenza. The findings were presented December 6 at the 57th annual meeting of the American Society of Hematology in Orlando, Florida. Patients with cancers of the immune system, like multiple myeloma, […]

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Experimental Alzheimer’s Drug J147 Shows Anti-Aging Effects

November 13, 2015

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Experimental Alzheimer's Drug Shows Anti-Aging Effects

New research from the Salk Institute shows that the experimental Alzheimer’s drug J147 has a host of unexpected anti-aging effects in animals. The Salk team expanded upon their previous development of a drug candidate, called J147, which takes a different tack by targeting Alzheimer’s major risk factor–old age. In the new work, the team showed […]

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Study Shows Diabetes Drug Significantly Reduces Risk of Heart Failure

November 10, 2015

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Diabetes Drug Reduces Risk of Heart Failure

A new clinical trial has shown that a type 2 diabetes drug significantly reduces hospitalizations and death from heart failure. The findings, from a large clinical trial known as EMPA-REG OUTCOME, were presented by Yale professor of medicine and clinical chief of endocrinology, Dr. Silvio E. Inzucchi, at the 2015 American Heart Association (AHA) Scientific […]

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New Chemical Compound Could Clear Up Cataracts

November 6, 2015

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New Chemical Eye Drops Could Clear Up Cataracts

A team of scientists has identified a chemical that could potentially be used in eye drops to reverse cataracts. Identified as a “priority eye disease” by the World Health Organization, cataracts — caused when the lenses of the eyes lose their transparency — affect more than 20 million people worldwide. Although cataracts can be successfully […]

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A New Paradigm for Cancer Research, One That Focuses on Improving Efficacy and Value

November 5, 2015

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A New Paradigm for Cancer Research

A newly published study from Yale University tackles the issue of value in cancer research, recommending a new paradigm for research that focuses on improving efficacy and value, as well as ensuring population health impact and generating new knowledge. The $100 billion federal government investment in the “War on Cancer,” has produced only relatively modest […]

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Yale Study Shows Nlrp6 Regulates Intestinal Antiviral Innate Immunity

October 26, 2015

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Yale Researchers Reveal Pathway of Resistance to Viral Infections in the Gut

New research from Yale University shows that the protein known as Nlrp6 plays a key role in the overall immune response that provides immediate defense against infection. The gut is an important barrier for the body, protecting it from pathogens that might otherwise cause illness. While scientists have investigated the intestinal immune response to bacterial […]

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A Light-Reflecting Balloon Catheter Repairs the Heart without Surgery

October 14, 2015

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New Technique Repairs Holes in the Heart Without Surgery

Using a catheter aided by UV light, researchers have developed a new technique to repair holes in the heart without surgery. Harvard-affiliated researchers have designed a specialized catheter for fixing holes in the heart by using a biodegradable adhesive and patch. The team reported in the journal Science Translational Medicine that the catheter has been […]

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New Epigenetic Algorithm Accurately Predicts Male Sexual Orientation

October 12, 2015

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Epigenetic Algorithm Accurately Predicts Male Sexual Orientation

By using epigenetic information from just nine regions of the human genome, a new algorithm can predict the sexual orientation of males with up to 70 percent accuracy. “To our knowledge, this is the first example of a predictive model for sexual orientation based on molecular markers,” said Tuck C. Ngun, PhD, first author on […]

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New Drug Significantly Reduces Mortality Rate After Stroke

October 12, 2015

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New Drug Significantly Cuts Mortality Rate After Stroke

New medical trials reveal that the intravenous drug Cirara significantly reduces brain swelling following a stroke. An existing drug administered intravenously reduces the chances of dying from major stroke by 60%, according to results of a phase II trial announced October 9 at the annual Neurocritical Care Society meeting in Scottsdale, Arizona. “We’ve never seen […]

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Nanoparticulate Carbon Black Found in the Lungs of Smokers

October 7, 2015

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Nanoparticulate Carbon Black Particles Start Emphysema

Two new studies identify the black material found in the lungs of smokers who died of emphysema as mostly insoluble nanoparticulate carbon black. Physicians could only guess – until recently – at the composition of the black material found in the lungs of smokers who died of emphysema. But research by Baylor College of Medicine […]

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