Biology

Challenging the Prevailing View – 45,000-Year-Old Ancient DNA Reveals Hidden Human History

Human DNA Evolution History Concept

The new findings challenge the prevailing view of human adaption.

The researchers used ancient genomes to reveal new information about the human history of adaption.

Ancient DNA, including samples from human remains that are around 45,000 years old, has helped researchers understand a previously unknown aspect of humanity’s evolution.

The new research, which was co-led by Dr. Yassine Souilmi, Group Leader at the Australian Centre for Ancient DNA at the University of Adelaide, was recently published in the journal Nature Ecology and Evolution.

“It was widely believed the genetics of our human ancestors didn’t change due to environmental pressures as much as other animals, due to our enhanced communication skills and ability to make and use tools,” Dr. Souilmi said.

“However, by comparing modern genomes with ancient DNA, we discovered more than 50 cases of an initially rare beneficial genetic variant becoming prevalent across all members of ancient human groups. In contrast to many other species, evidence for this type of adaptive genetic change has been inconsistent in humans. This discovery consequently challenges the prevailing view of human adaptation, and gives us a new and exciting insight into how humans have adapted to the novel environmental pressures they encountered as we spread across the planet.”

Examining ancient DNA has been crucial in revealing the secrets of human evolution, according to co-lead author Dr. Ray Tobler, an Adjunct Fellow at the University of Adelaide and a DECRA fellow at the Australian National University.

“We believed historical mixing events between human groups might have hidden signs of genetic changes in modern human genomes,” Dr. Tobler said.

“We examined DNA from more than 1,000 ancient genomes, the oldest which was around 45,000 years old, to see if certain types of genetic adaptation had been more common in our history than studies of modern genomes had suggested.”

Professor Christian Huber, a senior author of the research paper, is an Adjunct Fellow at the University of Adelaide and an Assistant Professor at Penn State University.

“The use of ancient genomes was crucial because they preceded major historical mixing events that have radically reshaped modern European genetic ancestry,” Professor Huber said.

“This allowed the recovery of historical signs of adaptation that are invisible to standard analysis of modern genomes.”

Reference: “Admixture has obscured signals of historical hard sweeps in humans” by Yassine Souilmi, Raymond Tobler, Angad Johar, Matthew Williams, Shane T. Grey, Joshua Schmidt, João C. Teixeira, Adam Rohrlach, Jonathan Tuke, Olivia Johnson, Graham Gower, Chris Turney, Murray Cox, Alan Cooper, and Christian D. Huber, 31 October 2022, Nature Ecology & Evolution.
DOI: 10.1038/s41559-022-01914-9

Researchers based at the Mayo Clinic, the Garvan Institute of Medical Research, the Max Planck Institute for the Science of Human History in Germany, the University of New South Wales, and Massey University in New Zealand also contributed to the research paper.

Established in 2005, the Australian Centre for Ancient DNA is a world leader in the research and development of advanced ancient DNA approaches for evolutionary, environmental, and conservation applications.

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  • Would be nice if there was some listing or categorization of these 50 genes.

    I would think chance may play a role as well. If someone becomes a king and establishes a dynasty, their genes will likely proliferate, because of the number of offspring, and increased likelihood that those offspring will have all their needs met.

  • Would cataclysmic bombardment of solar and cosmic radiation have mutation abilities in the human genome? Let's add a solar micro nova into the mix sometime in the sample period. It's written in many peer reviewed papers that 1) Our solar system has and does experience micro nova. 2) Bombardment of solar and cosmic radiation, particles and frequencies are world wide and the massive electromagnet pulses disrupt the very planets themselves and every living thing. Hence my question? Has human genome been altered globally and intermittently throughout history by the very universe we live in?

  • We are a product of our environment. As humans moved around following food sources,I would think that would have an impact on each generation being born and what was happening in space and on earth. Humans adapt or die. Floods, disease what they ate what they lived by the sea or in the mountains all of that would have had an effect on their DNA. I enjoyed reading this article, I wish it had more information on the subject and less giving all the names and university credits.... Not that credit isn't due.

  • I AM THE PRODUCT, OF WHAT I HAVE IN MY MIND AND SOUL SINCE I HAVE BEEN BORN AND THE DNA THAT MY TWO PARENTS AND ANCESTORS GAVE ME THRU THEM. WHAT I HAVE IN MY MIND CAME WITH ME SINCE I HAVE BORN, INCLUDING THE DEVELOPMENT OF MY BRAIN, BUT, FROM MY PARENTS FIRST GOAL FOR ME AND ALL MY SIBLINGS WERE ON HOW TO GET SECURE, ON HOW THEY TEACH US, THE RESPECT TO GOD AND HOW TO KNOW WHO HE WAS, AND THRU THAT; THAT WE WILL KNOW
    HOW ALWAYS TO BEHAVE, DOESN'T MATTER WHAT, IN A GOOD WAY TO ALWAYS BE A GOOD PERSON AND A GOOD CITIZEN WITH EVERYBODY AND EVERYTHING THAT IS IN THIS PLANET, (ANIMALS, FAUNA, WATERS, ETC.'ETC.) AND TO RESPECT EVERYTHING AROUND US AND EVERYBODY AS A HUMAN BEING AND IN ORDER FOR US, INCLUDING MY SIBLINGS TO BE A GOOD CITIZENS OF THIS WORLD AND IN ORDER TO BE A GOOD BELIEVERS OF GOD AND TO RESPECT HIM AND THAT DO NOT DESOBEY GOD TEACHINGS OF LOVE AND RESPECT FOR OTHERS AND TO EVERYBODY. AND THAT WAY, MY PARENTS, AND ALL MY FAMILY MEMBERS, A HUMBLE ONES, POORS, NOT RICH, THEY TEACH ME THAT DOING THAT, WE CAN EXPECT, THAT WE COULD GAIN OUR PLACE TO LIVE WITH GOD IN HEAVEN AFTER WE DIED.
    AND AFTER ALL THAT GOOD TEACHINGS FROM MY PARENTS, FAMILY MEMBERS AND OTHERS GOOD NEIGHBORS OF MY COMMUNITY, WHAT I HAVE DEVELOPED IN MY BRAIN AND WITH MY BRAIN CAME WITH ME AS PART OF MY BIRTH AS A HUMAN BEING, FROM MY PARENTS DNA AND GIFTED TO ME BY GOD AND ADDING TOO, THRU THE TEACHINGS AND E

  • I AM THE PRODUCT, OF WHAT I HAVE IN MY MIND AND SOUL SINCE I HAVE BEEN BORN AND THE DNA THAT MY TWO PARENTS AND ANCESTORS GAVE ME THRU THEM. WHAT I HAVE IN MY MIND CAME WITH ME SINCE I HAVE BORN, INCLUDING THE DEVELOPMENT OF MY BRAIN, BUT, FROM MY PARENTS FIRST GOAL FOR ME AND ALL MY SIBLINGS WERE ON HOW TO GET SECURE, ON HOW THEY TEACH US, THE RESPECT TO GOD AND HOW TO KNOW WHO HE WAS, AND THRU THAT; THAT WE WILL KNOW
    HOW ALWAYS TO BEHAVE, DOESN'T MATTER WHAT, IN A GOOD WAY TO ALWAYS BE A GOOD PERSON AND A GOOD CITIZEN WITH EVERYBODY AND EVERYTHING THAT IS IN THIS PLANET, (ANIMALS, FAUNA, WATERS, ETC.'ETC.) AND TO RESPECT EVERYTHING AROUND US AND EVERYBODY AS A HUMAN BEING AND IN ORDER FOR US, INCLUDING MY SIBLINGS TO BE A GOOD CITIZENS OF THIS WORLD AND IN ORDER TO BE A GOOD BELIEVERS OF GOD AND TO RESPECT HIM AND THAT DO NOT DESOBEY GOD TEACHINGS OF LOVE AND RESPECT FOR OTHERS AND TO EVERYBODY. AND THAT WAY, MY PARENTS, AND ALL MY FAMILY MEMBERS, A HUMBLE ONES, POORS, NOT RICH, THEY TEACH ME THAT DOING THAT, WE CAN EXPECT, THAT WE COULD GAIN OUR PLACE TO LIVE WITH GOD IN HEAVEN AFTER WE DIED.
    AND AFTER ALL THAT GOOD TEACHINGS FROM MY PARENTS, FAMILY MEMBERS AND OTHERS GOOD NEIGHBORS OF MY COMMUNITY, WHAT I HAVE DEVELOPED IN MY BRAIN AND WITH MY BRAIN CAME WITH ME AS PART OF MY BIRTH AS A HUMAN BEING, FROM MY PARENTS DNA AND GIFTED TO ME BY GOD AND ADDING TOO, THRU THE TEACHINGS AND EXAMPLE OF ALL THE GOOD TEACHERS AND PROFESSORS I HAD DURING MY STUDENT LIFE FROM 1ST GRADE TO 12 GRADE, TO UNIVERSIY AND COLLEGE AND ANY OTHERS APART COURSES AND DIPLOMAS THAT I HAVE. I RECENTLY DISCOVER THAT MY MOTHER SPARE TIME AND HOBBY AS PART OF TO BE ENJOYING THE NIGHTS LOOKING TO THE MISTERIES OF HEAVEN, SHE WAS TEACHING ME ANCIENT KNOWLEDGE ABOUT ALL STARS AND CONSTELLATION THAT I WENT TO REALIZE THAT SHE WAS TEACHING ME ASTRONOMY. AND BECAUSE THAT TODAY, I UNDERSTAND SOME OR ALL OF TESLA AND EINSTEIN CONCEPTS OF SCIENCE AND MORE OF WHAT EINSTEIN NEVER FOUND LIKE QUANTIC ENERGY ALL CONCEPTS.

  • Hybrid vigor....
    We're all hybrids...
    Be it mixed with annunaki for hybrid vigor humans + evolution of the grains we ate + evolution of organs(how we process vitamins/amino acids) + evolution of said vitamins/nutrients + how our body uses evolved vitamins/nutrients + hunting-use of brain + communication evolution n how that evolves hemispheres of the brain + how your brain circulates impulses +.... ....

    Annunaki we're around 50,000 bc...

    Look to the innovations in grain domestication like they have..
    You see, .,before ...there were no farmed grains, but after a great flood, ninmah brought exotic seeds from other planets...
    What you and every one is looking for is annunaki dna

    Ha... If it's even double helix.. which it isnt...you see, dna is a evolved genetic form...found on earth...if it's even ...ahhh
    The feeble brains of...

    I've smoked some ...in my day

  • Also. I am not disrespecting the Bible. Science will always be in it's infancy, forever and until our brains can handle concepts greater than infinite forever. Don't forget that. There is no ending to science, or the word for it's true meaning.
    I study the ancient religions or belief systems and science.
    Annunaki
    Maya
    Aztecs

    They all have creation stories
    Except the book of Enki is scientific based..with dna as a symbol in stone many thousands of years before we knew of dna

    To mine gold for their planets atmosphere? Possibly monatonic gold... And we just put gold on spaceships and suits like 60 yrs ago
    Aren't we a little behind the book of Enki?

    Now, science...
    Species of prehuman beings...
    What progressed humans?
    So the sample is 45,000 yrs old.
    Annunaki we're said to come around the Phanerozic eon, about 450,000 yrs ago

    And 55,000 yrs ago the annunaki married earth women apparently(the annunaki connection).
    Now this 45,000 yr old sample survived the great floods 30,000-20,000 years ago ....

    Theres texts ( Book of Enki) that existed far before paper..

    Hopefully bright minds see this..
    Now we gotta worry about AI enslaving humans again...for space travel and natural resources...the story is a repeat of 50,000 years ago

    Unless you already see time in cycles..(Maya calendar perhaps)

    To have these stories millennia before year 1ad...

    Is true science, true spiritual science, and scientific spirit. Their symbol of double helix was carved in stone...at least 5,000 yrs before we knew what recessive genes or dna was!

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