New Arthritis Treatment Prevents Cartilage Breakdown
Injectable material made of nanoscale particles can deliver arthritis drugs throughout cartilage. Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million…
Medicine
Researchers Find New Pathway to Regulate Immune Response
Researchers at The University of Texas at Arlington have found a potential new pathway to regulate immune response and potentially control inflammatory diseases of the…
Neuroscientists Identify Brain Activity Pattern Linked to Schizophrenia
Schizophrenia, a brain disorder that produces hallucinations, delusions, and cognitive impairments, usually strikes during adolescence or young adulthood. While some signs can suggest that a…
Study Shows Tiny DNA Modification Has Big Impact on Tumors
A simple modification of a DNA base in small areas of the genome may explain why glioblastoma tumors are so deadly, researchers at Yale and…
MIT Develops New Way to Help Blood Cells Regenerate Faster
Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment,…
Yale Scientists Explore the Role of Glucose Metabolism in Malaria
More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores…
Scientists Use Gene Therapy to Successfully Treat Mitochondrial Diseases
Mitochondrial disease is now thought to be the second most commonly diagnosed genetic disease worldwide, and, unfortunately, there are still no proven treatment strategies for…
Scientists Reveal the Key to Stem Cell Self-Renewal
Every skin cell on the human body is replaced weekly, with stem cells generating billions of specialized progeny that engage in an orchestrated scramble to…
Artificial Intelligence Improves Drug Combination Design
A new auto-commentary published in SLAS Technology looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can…
Protein ASTN2 Provides New Insight Into Autism and Other Brain Disorders
In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins—proverbial…
Scientists Provide New Insights Into the Origins of Genetic Diseases
A three-dimensional map showing an actin filament (blue) bound to a fragment of the cross-linking protein, filamin A (green). For human cells to form and…
New Molecular Details of Cancer Cells Could Lead to Improved Treatment
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment. Targeting a pathway that controls the movement of mitochondria, the powerhouses…
Physical Exercise Improves Cognition in Alzheimer’s Disease
A study by a Massachusetts General Hospital (MGH) research team finds that neurogenesis — inducing the production of new neurons — in the brain structure…
A New Model for Chronic Disease Pathogenesis and Treatment
Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common…
New Research Shows How Sickled Red Blood Cells Clump Together
One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain…
Scientists Discover How Microenvironments Regulate Stem Cell Development
Researchers from the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Jonsson Comprehensive Cancer Center have discovered an important…
Researchers Discover How to Stop Cell Death Associated with Multiple Diseases
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory…
New Imaging Technique Captures Detailed Information About Metabolism
Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple…