New HIV Therapy Boosts Immunity and Reduces Viral Replication
In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with…
Medicine
Molecular Switch Serves as New Target Point for Cancer and Diabetes Therapies
If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz- Forschungsinstitut für…
Scientists Discover Possible Treatment for Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth disease is the most common hereditary neuropathy and affects more than two million people worldwide. Researchers at the Max-Planck-Institute for Experimental Medicine and the…
Artificial Intelligence Uses “Self-Learning” to Make Cancer Treatment Less Toxic
Machine-learning system determines the fewest, smallest doses that could still shrink brain tumors. MIT researchers are employing novel machine-learning techniques to improve the quality of…
Scientists Create a Mouse That Eats Fat But Doesn’t Get Fat, Possible Treatment for Obesity
Yale scientists set out to create a morbidly obese mouse. They failed miserably. What they found was much more interesting. “We created a mouse that…
VPS13 Proteins Role in Neurological Disorders, Including Parkinson’s
Several gene mutations have been linked to Parkinson’s disease, but exactly how and where some of them cause their damage has been unclear. A new…
Hydrogen Peroxide-Sensing Molecule Helps Select Effective Cancer Therapy
MIT chemical engineers have developed a new sensor that lets them see inside cancer cells and determine whether the cells are responding to a particular…
Scientists Discover Surprise Link Between Metabolism and Immunity
In the search for obesity treatments, scientists recently zeroed in on a gene known as Nucleobindin-2 (Nucb2), which was believed to play a role in…
Scientists Identify New Way to Expand Stem Cells for Transplants
Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood…
Johns Hopkins Researchers Discover Cellular Defense Against Breast Cancer
Johns Hopkins researchers report they have demonstrated in mouse tissue grown in the lab that the cell layer surrounding breast milk ducts reaches out to…
Newly Developed Compounds Maintain Anti-HIV Activity Better Than FDA-Approved Medications
Antiretroviral therapies have worked wonders suppressing HIV replication and its progression to AIDS, but their effectiveness is deteriorating due to the constant development of drug…
Scientists Study “Magical” Royal Jelly for Clues to Control Cancer
Royal jelly, or milky-white “bee milk,” has long been known for its mysterious growth effects on future queen honey bees, while also hailed by some…
Scientists Suggest New Treatment for Rare Inherited Cancers
Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their…
New Test for Alzheimer’s Disease Directly Measures Synaptic Loss
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to…
New Genetic Study Links Stem Cell Mutations to Hydrocephalus
Hydrocephalus is characterized by a dangerous buildup of pressure on the brain caused by excessive amounts of fluid. Researchers have long believed that the condition,…
Nanoparticles Cure Blood Disorder, Provide Site-Specific Gene Editing
With the combined efforts of three Yale laboratories, researchers conducted the first demonstration of site-specific gene editing in a fetus, correcting a mutation that causes…
Lipid-Based Nanoparticles Enable Improved Therapy for Cystic Fibrosis Patients
Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of…
Study Shows Viral Suppression Helps Lower Risk for Many Types of Cancer
A new study by the Yale School of Public Health and partner institutions is the first to examine the potential cancer prevention benefits of prolonged…