Browsing: Calprotectin

Calprotectin is a calcium-binding protein predominantly found in the cytosol of neutrophils, a type of white blood cell. It is released during inflammation and serves as a biomarker for detecting inflammation in the body, particularly in the gastrointestinal tract. Calprotectin is clinically significant because its presence in feces correlates with intestinal inflammation, making it a valuable non-invasive diagnostic tool for differentiating between inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis, and functional disorders like irritable bowel syndrome (IBS). Elevated levels of calprotectin in stool samples indicate active intestinal inflammation and help guide treatment decisions, monitor disease activity, and predict relapses in patients with IBD.