…of the liver protein HNF4α, although the less common version usually appears only in specific situations, including chronic disease or metabolic stress caused by fasting or alcoholic fatty liver. This…
Search Results: Liver Cancer (221)
Acetate plus Bacteroides bacteria in the gut helps mice burn fat instead of carbs, mimicking keto effects and shrinking liver and fat mass. Credit: Shutterstock A team of Japanese researchers…
…a murine model of fatty liver disease, visualized by color-enhanced lipid droplets (pink) in liver tissue (green). Superimposed chemical structure of a newly discovered bile acid conjugate. Credit: Image courtesy…
…kidney disease, chronic neurological disease, chronic pulmonary disease, HIV/AIDS, cancer, liver disease, obesity, rheumatological disorders, and smoking). In addition, they collected data on the respiratory, neurological, cardiovascular, renal, gastrointestinal, and…
…and liver steatosis, which is a high amount of fat in the liver. Another form of fat accumulation is myosteatosis, which occurs when fat accumulates in the muscles. Since myosteatosis…
Chemotherapy reshapes gut bacteria in ways that send powerful signals throughout the body. These signals reprogram immune cells, making organs like the liver more resistant to metastatic cancer. Credit: Shutterstock…
…T-cell therapy successfully given to cancer patients that was reported in Science in 2020. That therapy not only delivered a transgene for a receptor targeting cancer cells, but knocked out,…
…cancer, who may be using CBD to treat pain or to try to reduce the side effects from anti-cancer drugs. “Taking CBD or marijuana might help your pain but could…
…MRI images. The researchers found that their imaging particles accumulated in the liver, as nanoparticles usually do. The mouse liver produces vitamin C, so once the particles reached the liver,…
…for conditions such as liver cancer and bone diseases, among others. “The next step will be to make better hormones, make new potent blockers, do animal studies, and move forward,”…
…component of LDL particles, in the bloodstream. Researchers identified how PCSK9 degrades LDL receptors via HLA-C, linking it to heart disease and cancer. A Canadian-led research team has made a…
A high-fat diet and obesity during pregnancy impact the fetal liver’s hematopoietic stem cell system. A newly published study shows that a diet high in fat during pregnancy harms stem…
…loss has sparked new concerns over its potential effects on muscle mass and strength. In mouse studies, the drug reduced lean mass primarily by shrinking organs like the liver rather…
…transplant-rejection drug cyclosporine, the cancer drug dacomitinib, and the antibiotic salinomycin. These could be rapidly tested in human volunteers and COVID-19 patients. The experiments also shed light on key processes…
…is nonalcoholic fatty liver disease, which occurs most often in people with overweight or obesity. Excess fat builds up in the liver and can cause diseases like cirrhosis (seen most…
…that mimics fasting effects. Research from USC demonstrates that periodic adherence to a diet that simulates fasting can lower insulin resistance, decrease liver fat, rejuvenate the immune system, and reduce…
…is copied and preserved by an enzyme (a type of protein) called DNMT1. This enzyme ensures, for example, that a dividing liver cell turns into two liver cells and not…
…that exposure to BPA during pregnancy caused chronic inflammation in the offspring’s intestines and liver. The researchers also noted signs of increased gut permeability — or leaky gut — and…