Unlocking T Cells’ Tactical Advantage Against Tuberculosis
By tracking T cell activity, researchers uncover promising tuberculosis vaccine and drug targets. La Jolla Institute for Immunology (LJI) is working to guide the development…
La Jolla Institute for Immunology News
Find the latest research news from the La Jolla Institute for Immunology (often abbreviated as LJI and previously known as the La Jolla Institute for Allergy and Immunology), a non-profit research organization in La Jolla, California. It is home to three research centers that focus the efforts of collaborative groups of researchers to accelerate progress toward the development of new treatments and vaccines to prevent and cure autoimmune conditions, cancer, and infectious disease.
Revolutionizing Vaccine Research: The Power of a New Algorithm
Computational biologists harness machine learning to make sense of immune system data. Immune system researchers have designed a computational tool to boost pandemic preparedness. Scientists…
Pirola Panic? T Cells Might Be Our Secret Weapon Against the Latest COVID “Variant of Concern”
LJI scientists harness bioinformatics to predict how T cells may adapt to fighting the highly mutated Pirola variant. In August, researchers detected a new SARS-CoV-2…
Sugar vs. Fat: Unraveling the Metabolic Mysteries of MAIT Cells
Scientists at the LJI have discovered that MAIT cells’ metabolism can be adjusted to combat various pathogens, potentially leading to innovative therapeutic strategies. An unconventional…
Scientists Solve Cell Survival Mystery
The new findings have the potential to improve our understanding of cancers and a multitude of other diseases. Researchers at La Jolla Institute for Immunology…
Unlocking the Mystery of Asthma: Study Identifies a Long-Term Treatment Target
Research has uncovered the mechanism by which the inflammatory protein “LIGHT” causes airway remodeling and chronic respiratory issues. Scientists at La Jolla Institute for Immunology…
Failed Clinical Trial Leads to Scientific Breakthrough: Investigating Cancer Drug Toxicity Leads to Critical Discovery
Researchers uncover a new strategy to avoid cancer immunotherapy side effects. It’s not often that a failed clinical trial leads to a scientific breakthrough. When…
A Small Mutation Can Make Zika Virus Even More Dangerous – And Potentially Breakthrough Pre-Existing Immunity
How Zika outbreaks could happen, even in areas with prior immunity. Scientists at La Jolla Institute for Immunology (LJI) have discovered that the Zika virus…
New Therapies Could Stop T Cells From Attacking Brain Cells in Parkinson’s Disease
LJI Scientists uncover new targets for treating Parkinson’s disease. Scientists at La Jolla Institute for Immunology (LJI) have found that people with Parkinson’s disease have…
Clever Human Antibodies Neutralize Ebola Virus – And Its Deadly Relatives
LJI team uncovers how one odd antibody does some heavy lifting. Researchers at La Jolla Institute for Immunology (LJI) are designing better therapies for treating Ebola virus…
Weird DNA Structures May Drive Cancer Development
LJI researchers shed light on the role of TET enzymes in genomic stability and cancers. Scientists at the La Jolla Institute for Immunology (LJI) have…
Current COVID-19 Vaccines Teach T Cells To Fight Omicron Variant
Scientists at La Jolla Institute for Immunology (LJI) have found that four COVID-19 vaccines (Pfizer-BioNTech, Moderna, J&J/Janssen, and Novavax) prompt the body to make effective,…
COVID-19 Case Severity: How Genetic Variations Affect Our Immune Cells
New LJI research shows how a range of critical immune cells respond to SARS-CoV-2. New research shows how genetic variations linked to severe cases of…
Vitamin C Is a Key Ingredient for Immune Cell Function – A Leg Up in Treating Autoimmune Diseases
Harnessing the combined power of Vitamin C and TET proteins may give scientists a leg up in treating autoimmune diseases. You can’t make a banana…
A Clue to How Some Fast-Growing Cancer Tumors Hide in Plain Sight
New LJI research could guide the development of more effective cancer immunotherapies. The glow of a panther’s eyes in the darkness. The zig-zagging of a…
Research Shows Exposure to Common Cold Coronaviruses Can Teach the Immune System to Recognize SARS-CoV-2
Researchers caution: It is too soon to say whether pre-existing immune cell memory affects COVID-19 clinical outcomes. Your immune system’s “memory” T cells keep track…
Scientists Discover Biomarkers That Predict the Risk of Developing Asthma
Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors, and a diverse cast of immune cells. In their latest study,…