Is Modern Society Too Clean, Leading to Defective Immune Systems in Children?

Child Cleaning

A new study by researchers dismisses the theory that modern society being too clean leads to defective immune systems in children.

Being Clean and Hygienic Need Not Impair Childhood Immunity

The theory that modern society is too clean, leading to defective immune systems in children, should be swept under the carpet, according to a new study by researchers at UCL and the London School of Hygiene & Tropical Medicine.

In medicine, the ‘hygiene hypothesis’ states that early childhood exposure to particular microorganisms protects against allergic diseases by contributing to the development of the immune system.

However, there is a pervading view (public narrative) that Western 21st century society is too hygienic, which means toddlers and children are likely to be less exposed to germs in early life and so become less resistant to allergies.

In this paper, published in the Journal of Allergy and Clinical Immunology, researchers point to four significant reasons which, they say, disprove this theory and conclude we are not “too clean for our own good.”

Lead author, Emeritus Professor of Medical Microbiology Graham Rook (UCL Infection & Immunity), said: “Exposure to microorganisms in early life is essential for the ‘education’ of the immune and metabolic systems.

“Organisms that populate our guts, skin, and airways also play an important role in maintaining our health right into old age: so throughout life we need exposure to these beneficial microorganisms, derived mostly from our mothers, other family members, and the natural environment.

“But for more than 20 years there has been a public narrative that hand and domestic hygiene practices, that are essential for stopping exposure to disease-causing pathogens, are also blocking exposure to the beneficial organisms.

“In this paper, we set out to reconcile the apparent conflict between the need for cleaning and hygiene to keep us free of pathogens, and the need for microbial inputs to populate our guts and set up our immune and metabolic systems.”

In a review of evidence, the researchers point to four factors.

  • Firstly, the microorganisms found in a modern home are, to a significant degree, not the ones that we need for immunity.
  • Secondly, vaccines, in addition to protecting us from the infection that they target, do a lot more to strengthen our immune systems*, so we now know that we do not need to risk death by being exposed to the pathogens.
  • Thirdly, we now have concrete evidence that the microorganisms of the natural green environment are particularly important for our health; domestic cleaning and hygiene have no bearing on our exposure to the natural environment.
  • Finally, recent research** demonstrates that when epidemiologists find an association between cleaning the home and health problems such as allergies, this is often not caused by the removal of organisms, but rather by exposure of the lungs to cleaning products that cause a type of damage that encourages the development of allergic responses.

Professor Rook added: “So cleaning the home is good, and personal cleanliness is good, but, as explained in some detail in the paper, to prevent spread of infection it needs to be targeted to hands and surfaces most often involved in infection transmission. By targeting our cleaning practices, we also limit direct exposure of children to cleaning agents

“Exposure to our mothers, family members, the natural environment, and vaccines can provide all the microbial inputs that we need. These exposures are not in conflict with intelligently targeted hygiene or cleaning.”

Reference: “Microbial exposures that establish immunoregulation are compatible with Targeted Hygiene” by Graham A.W. Rook, BA, MB, BChir, MD and Sally F. Bloomfield, PhD, 5 July 2021, Journal of Allergy and Clinical Immunology.
DOI: 10.1016/j.jaci.2021.05.008

* Vaccinology: time to change the paradigm? The Lancet Infectious Diseases 2020

** Food allergy as a biological food quality control system. Cell 2021

** Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions? Nature Reviews Immunology 2021

1 Comment on "Is Modern Society Too Clean, Leading to Defective Immune Systems in Children?"

  1. This isn’t msm we don’t need to be fed half truths to respond according to the truth (most plausible theory).
    – Is Modern Society Too Clean, Leading to Defective Immune Systems in Children?
    The answer should be yes, you are intentionally making wrong conclusions.
    If you don’t get what I’m saying read again and take a look at the original paper, I won’t tell you why either, use your brain.

    The author of the paper goes on to say:
    “Halting the flow of misinformation
    As suggested in a previous 2016 review, if we are to get the public to adopt targeted hygiene behavior, we need to halt the misrepresentation of hygiene as an inevitable cause of immunoregulatory disorders. Such misrepresentation is widespread in the media and in the medical literature.
    We must discourage suggestions in the media or published articles that we should relax hygiene standards and ensure that such statements are replaced by instructions for intelligent use of targeted hygiene”

    I see this article followed the suggestion. I don’t need to be fed BS because you think I’m too dumb to make appropriate decisions given the evidence.

    You are spreading misinformation to prevent misinformation, think about that.

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