Search Results: Reprogramming cells (180)

…cells, overcomes the problem of entirely erasing cell identity by halting reprogramming part of the way through the process. This allowed researchers to find the precise balance between reprogramming cells,…

…naïve cell reprogramming, and this knowledge gap limited the design of reprogramming conditions.” The low efficiency of naïve reprogramming suggests the presence of barriers that limit cells in reaching the…

…stem cells are uniquely capable of reprogramming, challenging current reprogramming theories and opening possibilities for stem cell-based treatments. A research team from the University of Toronto has identified that neural…

…stem cells to become adult cells of some other type. More recently, scientists have been finding ways to do this reprogramming more directly – straight from one mature cell type…

…Engineering a Cell Into a New State MIT and Harvard researchers have developed a novel computational technique that can efficiently identify optimal genetic interventions in cellular reprogramming using fewer experiments….

…of germ cells, or the human primordial germ cells (hPGCs), a hallmark event known as epigenetic reprogramming —in which the inherited parental “memory” of cells, present on its DNA, is…

Scientists have developed a revolutionary technique, termed “transient-naive-treatment (TNT) reprogramming.” This method allows human cells to be reprogrammed to more closely resemble embryonic stem cells, addressing a longstanding issue in…

…Dr. Amrita Iyer, a researcher at Baylor College of Medicine and lead author of a new study published in eLife, “these cells allow the brain to detect sounds.” Hair cells…

Induced pluripotent stem cells — known as iPS cells, which act very much like embryonic stem cells — are here growing into heart cells (blue) and nerve cells (green). Credit:…

Cellular reprogramming can reverse aging in mesenchymal stem/stromal cells (MSCs). A new study reveals the molecular mechanisms behind this, shedding light on MSC aging and potential pharmacological strategies to combat…

…an adult cell into what are known as induced pluripotent stem cells, or iPS cells. Induced pluripotent stem cells can become nearly any type of cell in the body, regardless…

…when blood vessel cells are created from special stem cells called induced pluripotent stem cells, age-related molecular changes are wiped clean. So, most knowledge about how blood vessel cells age…

…Proof-of-concept study represents first successful attempt to reverse the aging clock in animals through epigenetic reprogramming. Scientists turned on embryonic genes to reprogram cells of mouse retinas. Approach reversed glaucoma-induced…

…tissue into those closely resembling beating heart cells. Last year, these scientists transformed scar-forming heart cells, part of a class of cells known as fibroblasts, into beating heart-muscle cells in…

…stem cells, then into neurons that were exposed to stress hormone and subsequently observed by the study team. Credit: Yale School of Medicine Reprogramming Cells to Understand Trauma Response “Reprogramming…

…can receive a transplant of islet cells, which include beta cells. While islet cell transplant therapy replenishes beta cells, it’s not without challenges. First, as they rely on human donors,…

Liver cells were partially reprogrammed into younger cells (red) using Yamanaka factors (white). The cell nuclei (blue) and cytoskeletal proteins (green) are also shown. Credit: Salk Institute Salk scientists improve…

…new discovery: “We found out that in totipotent cells, the mother cells of stem cells, DNA replication occurs at a different pace compared to other more differentiated cells. It is…