Search Results: Reprogramming cells (180)

Left: mouse astrocytes (green) before reprogramming; Right: neurons (red) induced from mouse astrocytes after reprogramming with PTB antisense oligonucleotide treatment. Credit: UC San Diego Health Sciences Inhibiting a single gene…

…“killer” — T cells, which can then kill cancer cells or other target cells. The researchers studied the squeezed B cells in culture and found that they could expand antigen-specific…

…of cells from Arabidopsis and soybeans. New research reveals a reproducible way of studying cellular communication among varied types of plant cells by “bioprinting” these cells via a 3D printer….

…In each case, the cells responded by uniquely reprogramming the location and amount of each tRNA modification. If the cells lost the ability to reprogram the modifications, they were much…

…will divide to produce the sperm (meiocytes) are surrounded by cells that nourish them. These nurse cells are called tapetal cells. CLSY3 Protein Triggers Epigenetic Signals The John Innes Centre…

During skin development, the transcription factor SOX9 guides stem cells to become either epidermal cells or hair follicle cells, a process that can also lead to certain cancers when SOX9…

…and molecular genetics at the Medical College of Wisconsin. Stem cells to liver cells Last year, Bhatia and Rice reported that they could induce liver cells to grow outside the…

…and computer science (EECS), in 2009. His team used that earlier version to fuse adult cells with embryonic stem cells, allowing the researchers to observe the genetic reprogramming that occurred…

…by the immune system. This is because—for the most part—they more closely resemble cells that belong in the body than pathogens, such as bacterial cells or viruses. The goal of…

…the use of human blastocysts and, importantly, at an unprecedented scale, accelerating our understanding and the development of new therapies,” Professor Polo said. Reprogramming Skin Cells Into Embryo-Like Structures The…

…are most effective when they include two types of T cells. Killer T cells directly attack cancerous or infected cells. Helper T cells act as the immune system’s conductors—detecting threats,…

…produce protective antibodies, had shifted toward a pro-inflammatory state. T helper cells, particularly a subset resembling Tfh17 cells, were dramatically expanded beyond normal levels. These cells play crucial roles in…

…reprogramming of their activity: they begin producing a molecule locally—the chemokine CCL3—which promotes tumor growth,” explains Mikaël Pittet. In light grey, tumor cells. Among the infiltrating neutrophils, some do not…

…production of myelinating cells. Researchers at Case Western Reserve School of Medicine have discovered a technique that directly converts skin cells to the type of brain cells destroyed in patients…

…in animal studies. Rather than focusing on directly killing cancer cells, this pioneering method stops the cells from adapting in ways that allow them to resist treatment. By blocking this…

…into biology. “By reprogramming interactions between cells, new multicellular structures can be created, analogous to the way stone and brick can be arranged into different structural elements like walls, archways…

…cycle to produce new blood cells. Blood-forming progenitor cells normally produce only new blood cells. However, the introduction of Yamanaka factors sometimes — but not always — help these blood-forming…

…pioneers of this cellular reprogramming won a Nobel Prize in 2012. However, going in the opposite direction, that is, causing stem cells to differentiate into specialized body cells, not to…