…associate professor in Harvard’s Department of Stem Cell and Regenerative Biology (SCRB). The principle of direct lineage reprogramming of differentiated cells within the body was first proven by SCRB co-chair…
Search Results: Reprogramming cells (180)
…throughout the body in rodents can ameliorate the hallmarks of aging by mimicking the adaptability that is common to more youthful cells. Myc’s Role in Muscle Reprogramming Of the four…
…turn adult fibroblast cells back into pluripotent stem cells. Such induced pluripotency would allow the cells to be coaxed into different types of mature cells, including nerve and heart cells….
…turns back the cellular clock, greatly aiding the reprogramming of mature cells. An exhaustive analysis of factors that allow mature cells to become like embryonic stem cells again has revealed…
Researchers at Osaka Metropolitan University have innovatively reprogrammed canine stem cells from urine to create induced pluripotent stem cells (iPSCs) without feeder cells. This breakthrough in non-invasive, pain-free stem cell…
…from human skin cells through genetic reprogramming. iPS cells were later used to generate multiple human cell types, such as neurons and heart cells — yet blood-forming stem cells remained…
…cells could potentially use cathartocytosis to jettison waste in other, more worrisome situations, like giving mature cells that ability to start to act like cancer cells. The Downside to Downsizing…
Vaccines train adaptive immune cells to target pathogens, but innate immune cells lack this memory. Researchers found small molecules, including some steroids, that can enhance innate immune responses without adverse…
…Hydrogel Converts Cancer Cells Into Stem Cells A hydrogel, a type of soft matter, developed at Hokkaido University successfully reverted cancer cells back to cancer stem cells within 24 hours,…
…cells. Using genes inserted into two types of human cells, fibroblasts and glial cells, researchers showed that it is possible to reprogram other cells to become nerve cells directly in…
Red blood cells successfully made via induced pluripotent stem cells from a Diamond-Blackfan anemia (DBA) patient. Control iPS cells (left) and DBA iPSc cells (right), showing that DBA blood cells…
…M2 cells. Despite the evident importance of M2 macrophages, real-time monitoring of M2 had remained a challenge. Real-Time Monitoring of Macrophage Reprogramming The team developed a novel M2 probe, CDg18,…
…reprogramming gene activity, and passing stress memory to daughter cells. New research reveals how cancer cells endure stress and survive. Publishing in Molecular Cell, an international research team identified mechanisms…
…several different cell types, including nerve cells, liver cells and heart cells. Furthermore, because these reprogrammed cells can be generated with nuclear genetic material from a patient, there is no…
The stylized yeast cells depicted in several leaves and flower petals are an artist’s interpretation of how scientists, using the tools of synthetic biology, genetically engineered yeast to brew plant-based…
…to predict gene combinations that are most likely to induce a desired reprogramming transition, such as to cause diseased cells to behave as healthy cells. The approach that results from…
…into a tiny ball of cells, the morula, in the mother’s womb. This ball contains pluripotent stem cells, blank slates that can be programmed into any cell in the body,…
Projection neurons of the cerebral cortex targeted for reprogramming are displayed in green. A newly published study from Harvard biologists shows how neurons can be dramatically changed from one type…