Search Results: Reprogramming cells (180)

…flexible electronics and human stem cells – the body’s ‘reprogrammable’ master cells – to better integrate with the nerve and drive limb function. Credit: University of Cambridge Using reprogrammed muscle…

…granulosa cells surrounding it, if we can induce them into pluripotent cells and turn those cells into oocytes, aren’t we killing two birds with one stone?” Granulosa cells tend to…

…cells, using a technique called reprogramming. The reprogrammed cells changed shape to look like thymus cells and were also capable of supporting development of T cells in the lab –…

…in T cells, significantly boosting their ability to kill cancer cells. The master regulator is called BATF3 and is one of several genes that the researchers identified and tested for…

…Berger. “This reprogramming made them significantly better at recognizing and killing cancer cells.” In simpler terms, blocking this protein forces the immune cells to adapt their metabolism, turning them into…

…cells to coordinate their response. “Cytokines are potent and highly effective at stimulating the immune cells to eliminate cancer cells,” Tong said. “The problem is they’re so potent that if…

…blood of mice by reversing, or re-programming, the stem cells that produce blood. Stem cells form the origin of all the cells in the body and can divide an unlimited…

…been able to revert ‘adult’ human cells (for example, liver, lung, or skin) into pluripotent stem cells with slightly different properties that predispose them to becoming cells of certain types….

…tumor cells. In a preclinical study, researchers from the Institut Pasteur and Inserm successfully triggered a potent anti-tumor immune response by reprogramming how malignant B cells die. Their work demonstrated…

…lifespan. By reprogramming the gene regulatory circuit that controls aging, cells periodically switch between two detrimental states, slowing their degeneration. This innovative approach, tested on yeast cells, led to an…

…diabetes, the researchers modified the cells to recognize and protect human beta cells. They introduced the engineered immune cells into mice that had received a transplant of human islet cells,…

A recent study reveals that skin cells taken from Alzheimer’s patients can be reprogrammed to generate brain cells, providing insights into dementia and offering potential for early diagnosis and new…

Researchers from Japan, discover mitochondrial transfer from cancer cells to immune cells and metabolic reprogramming of the tumor microenvironment as a key immune evasion strategy. Targeting mitochondrial transfer can help…

…biopsy, which could enhance understanding of the disease and lead to novel treatment approaches. The scientists transformed skin cells taken from patients with late-onset Alzheimer’s disease into brain cells called…

…Applications The 2012 Nobel Prize to Shinya Yamanaka demonstrated that it is possible to obtain stem cells from “differentiated” cells just by expressing four factors, including a Sox (Sox2) and…

…cells known as stem cells. The interest in stem cells as an attractive therapy for a range of diseases rapidly gained momentum after 2012, when John B. Gurdon and Shinya…

…treatment that blocks an age-related protein restored cartilage in aging and injured joints by reprogramming existing cells rather than using stem cells. Researchers at Stanford Medicine report that blocking a…

…revert to basic skin cells and lose their ability to produce hair follicles. So we were faced with a Catch-22: how to expand a sufficiently large number of cells for…