New research from the University of East Anglia has shown that heavy drinkers, particularly those in their 50s and 60s consuming around 10 units a day, may risk muscle loss and frailty in later life. The study, which considered factors such as body size, protein consumption, and physical activity, found that higher alcohol consumption was associated with lower muscle mass, further highlighting the potential harm of excessive drinking on muscle health during middle and early older age.
According to a new study by the University of East Anglia, individuals who consume alcohol heavily may be jeopardizing their muscle health and predisposing themselves to frailty as they age. The study utilized statistical models to demonstrate that those with the least muscle mass were consuming at least 10 units of alcohol daily, equivalent to about one bottle of wine.
Given that individuals with larger bodies generally possess more muscle mass, the researchers adjusted their analysis for body size. They also considered other influencing factors, such as the level of physical activity and protein intake of the subjects.
The team says that their findings, mainly in people in their 50s and 60s, suggest another reason to cut back on booze.
Prof Ailsa Welch, from UEA’s Norwich Medical School, said: “Losing muscle as we age leads to problems with weakness and frailty in later life. Alcohol intake is a major modifiable risk factor for many diseases, so we wanted to find out more about the relationship between drinking and muscle health as we age.”
The team studied data from the UK Biobank – a large-scale database of anonymized lifestyle and health information from half a million people in the UK. They looked at data for nearly 200,000 people aged between 37 and 73 years.
Dr. Jane Skinner, also of UEA’s Norwich Medical School, said: “We studied how much alcohol people were drinking and compared it with how much muscle they had, according to their body size. We also took into account things like how much protein they consumed, their levels of physical activity, and other factors that could make a difference to how much muscle they might have. Most of the people were in their 50s and 60s. We found that those who drank a lot of alcohol had a lower amount of skeletal muscle compared to people who drank less, after we took into account their body sizes and other factors.”
“We saw that it really became a problem when people were drinking 10 or more units a day – which is the equivalent of about a bottle of wine or four or five pints. Alcohol consumption and muscle mass were measured cross-sectionally – in people at the same time – so we can’t be sure of a causal link,” she added.
Prof Welch said: “This study shows that alcohol may have harmful effects on muscle mass at higher levels of consumption. We know that losing muscle as we age leads to problems with weakness and frailty, so this suggests another reason to avoid drinking high amounts of alcohol routinely in middle and early older age,” she added.
Reference: “Alcohol Consumption and Measures of Sarcopenic Muscle Risk: Cross-Sectional and Prospective Associations Within the UK Biobank Study” by Jane Skinner, Lee Shepstone, Mary Hickson and Ailsa A. Welch, 25 May 2023, Calcified Tissue International.
DOI: 10.1007/s00223-023-01081-4
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