Search Results: Reprogramming cells (180)

…work has shown that liver cells regenerate by reprogramming their gene expression to return to a fetal-like progenitor state, where they can multiply before transitioning back into fully mature, functional…

Researchers have developed a molecular device with remarkable reconfigurability. Unlike the brain, which changes physical connections, this device achieves reconfiguration by reprogramming its logic. Researchers have engineered a brain-like molecular…

…into blood vessels and nerve cells. Researchers at the Indiana University School of Medicine have developed technology that has the potential to be a treatment for traumatic muscle loss. This…

…and fruit flies through drugs, genetic alterations, dietary changes, and cellular reprogramming (which involves reverting some of the body’s cells to a “younger,” more primitive state). It’s always challenging to…

…cells contained the biochemical markers of hepatocytes, maturing liver cells. Two more types of cells were added, endothelial and mesenchymal cells. Two days later, the cells assembled themselves into a…

…from a pig model of HCM. The heart cells were chemically removed from the tissue and replaced with healthy human heart muscle cells. They later compared these cells with cardiac…

…modifications inside the cells. This approach also makes it possible to activate T cells, a capability that other gene-editing strategies have struggled to achieve. T cells act as the immune…

…pluripotent stem cells (iPSCs), a lab generated cell type designed for flexibility. Unlike embryonic stem cells, iPSCs are created by taking adult cells, such as skin or blood cells, and…

…meaning it contains very few immune cells capable of attacking cancer. Reprogramming the immune landscape of glioblastoma “Patients with glioblastoma have not benefited from immunotherapies that have transformed patient care…

…stem cells, coaxing those stem cells to become various types of liver cells and, then, seeding those human liver cells into a rat liver with all of its own cells…

…skin cells, into more stem-cell-like cells that are pluripotent, which means they have the ability to become many different types of cells. “Our laboratory previously showed that these factors can…

…such as engineering better tumor-killing lymphocytes or reprogramming stem cells to in vivo gene therapy to treat genetic diseases in the eye, muscle, or liver,” Qi says. “It is on…

…that could do this, the team turned to induced pluripotent stem cells (iPSCs). These cells are created by reprogramming adult skin or blood cells into a flexible, stem-like state, then…

A newly proposed model suggests cancer cells may resist treatment not just through genetic mutations, but by dynamically reprogramming their gene activity. Credit: Shutterstock Cancer cells may “learn” to survive…

…Unlike cell-based cancer immunotherapies that manipulate immune cells outside of the body and transfer them into patients, the implantable immuno-material approach activates endogenous immune cells inside a patient’s own body…

…University Hospital to extract a type of lung cell known as human lung alveolar type 2 cells. By reprogramming these cells back to their earlier ‘stem cell’ stage, they were…

…cells tasked with killing cancer cells into “seeing” them as healthy. They also recruit and nurture immune cells, like regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs), that inhibit…

Yale researchers found that TH17 cells can switch from a pro-inflammatory state to a regulatory cell that limits inflammation, based on mouse model experiments. New research shows that TH17 cells…