New Test for Alzheimer’s Disease Directly Measures Synaptic Loss
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to…
Alzheimer’s
Neuroscientists Link APOE4 Gene to Alzheimer’s
People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients…
Variation of PM20D1 Gene Linked To Increased Risk of Developing Alzheimer’s Disease
An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program…
Biochemists Discover A New Target For Patients With Diabetes
Focusing on a simple hormone in us all, a Yale researcher has found specific forms of it that poke toxic holes in cells — a…
Boosting TREM2 Protein Levels Improves Alzheimer’s Symptoms
Scientists have known for about five years that mutations in the gene TREM2 increase a person’s risk of developing Alzheimer’s disease. Now, UCLA researchers have…
Shining Molecules Detect Tau Pathology in Alzheimer’s Disease
Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain. They…
Monkeys and Humans Share Same Signs of Alzheimer’s
Very old rhesus monkeys exhibit similar patterns of brain pathology as human Alzheimer’s patients, researchers report in the journal Alzheimer’s & Dementia: The Journal of…
Yale Researchers Develop a New Way to Diagnosing Alzheimer’s Disease
Using a new technique called vibrational spectroscopy, doctors at Yale have developed a novel way to scan for Alzheimer’s disease. Deep within our brains is…
Blocking HDAC2 Enzyme May Reverse Memory Loss Caused by Alzheimer’s Disease
Research from MIT suggests a new approach to developing treatments for Alzheimer’s disease, revealing a new way to reverse memory loss by blocking an enzyme…
Study Shows Lysosomes Greatly Accelerate Formation of Amyloid Plaques
New research from Yale University shows that increased lysosomes in neural projections in a mouse model of Alzheimer’s greatly accelerated formation of amyloid plaques. Lysosomes…
New Drug Completely Erases Evidence of Alzheimer’s in Mouse Models
Research from Yale University reveals that a new drug can restore memories and connections between brain cells in mice with a model of Alzheimer’s disease….
New Drug Compound Halts Alzheimer’s, Appears to Reverse Some Neurological Damage
New research from Washington University School of Medicine in St. Louis shows that levels of the tau protein can be reduced, and some of the…
Common Mechanism May Be Responsible for the Spread of Alzheimer’s and CTE
A newly published study from UC San Francisco reveals that a shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic…
STEP Protein Linked to Alzheimer’s May Also Play a Role in Schizophrenia
New research from Yale University shows that an increase in the STEP (STriatal-Enriched protein tyrosine Phosphatase) protein leads to a disruption of synaptic function and…
New Study Shows Fructose Alters Brain Genes, Which Can Lead to Disease
A new study by researchers at UCLA reveals that genes in the brain can be damaged by fructose, leading to diseases like diabetes, cardiovascular disease,…
New Research Shows Hyperactive Neurons May Trigger Alzheimer’s
New research from Yale University shows that an increase in neuronal activity can spur the creation of plaques and toxic amyloid beta peptides, which are…
Experimental Alzheimer’s Drug J147 Shows Anti-Aging Effects
New research from the Salk Institute shows that the experimental Alzheimer’s drug J147 has a host of unexpected anti-aging effects in animals. The Salk team…
Enhanced-Sensitivity NMR Reveals New Details on Protein Structure
Using a new technique based on dynamic nuclear polarization, scientists hope to gain more insight into protein structure and function. Proteins can fold in different…