Scientists have visualized, for the first time, how a key sensory protein detects both cold…
Browsing: CryoEM
Cryo-electron microscopy (CryoEM) is a revolutionary technique in structural biology that allows for the visualization of biological molecules in near-native states at atomic resolutions. This method involves rapidly freezing biological samples in a way that preserves their natural structure without the need for dyes or fixatives. The frozen samples are then imaged with an electron microscope, which captures thousands of projections that are computationally combined to produce high-resolution three-dimensional structures of complex proteins, viruses, and other cellular components.
The model enables the study of the fundamental interactions that underlie neurodegenerative disease. Researchers from…
Scientists used advanced cryo-EM imaging to reveal how glutamate activates brain receptors, paving the way…
Electron microscopy images reveal crucial structures and mechanisms within the molecular machinery that certain bacteria…
Cryo-EM and MD simulations reveal the mechanism by which the potent neurotoxin α-latrotoxin forms calcium-permeable…
Recent findings illustrate how RNA polymerase interacts with DNA to initiate transcription, captured in milliseconds…
Max Plank researchers from Dortmund have revealed the molecular mechanisms by which ring-shaped formin proteins…
A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat,…
Scientists captured the first true-to-life 3D image of the thick filament in mammalian heart muscle.…
An advance in cryo-EM could be a significant boon for research on potential cancer therapies.…
Scientists identified how DDM1 enables DNA methylation by displacing histones, preserving epigenetic memory across generations…
A molecule regulating PIEZO ion channels could lead to therapies for obesity, osteoporosis, and inflammation.…
Scientists reveal how the Langya virus infects human cells, paving the way for future vaccines…
Collaborative efforts from teams at the MPI Institutes located in Dresden, Dortmund, Frankfurt am Main,…
A recent study conducted by a multidisciplinary team of researchers sheds light on the underlying…
Exciting new findings shed light on the interaction between the protein calmodulin and an ion…
A group of scientists collaborated to release comprehensive structures of the entire human opioid receptor…
Albicidin offers hope against drug-resistant bacteria through a novel mechanism targeting DNA gyrase. A powerful…