Building a Better Opioid: Scientists Take Another Step Forward
A group of scientists collaborated to release comprehensive structures of the entire human opioid receptor family, with the aim of facilitating the development of more…
CryoEM News
Antibiotic Breakthrough: The Power of a Plant-Derived Toxin
A powerful plant-derived toxin with a unique way of killing harmful bacteria has been identified as one of the most promising new antibiotics in decades….
A How-To Guide to Designing Cancer Drugs
Scripps Research scientists have identified how the structure of the PI3Kα protein changes in cancer cells, providing insight into potential drug-targeting strategies. Understanding the structure…
Profound Implications: New Research Challenges a 70-Year-Old Theory of Protein Folding
The findings of the study call into question a long-held belief about the way proteins fold within our cells and have significant ramifications for the…
Scientists Solve a 50-Year Mystery – How Do Bacteria Move?
University of Virginia scientists have solved a decades-old mystery. Researchers from the University of Virginia School of Medicine and their colleagues have solved a long-standing…
Researchers Discover a Key COVID “Weak Spot”
The University of British Columbia researchers have discovered a key vulnerability of major coronavirus variants. The University of British Columbia researchers uncovered a key vulnerability…
Breakthrough in Battery Design: First Realistic Portraits of Squishy Layer That’s Key to Battery Performance
Cryo-EM snapshots of the solid-electrolyte interphase, or SEI, reveal its natural swollen state and offer a new approach to lithium-metal battery design. Lithium metal batteries…
Nanotechnology Enables 3D Visualization of Crucial RNA Structures at Near-Atomic Resolution
Combination of nucleic acid nanotechnology and cryo-EM gives unprecedented insights into the structures of large and small RNAs, advancing RNA biology and drug design. We…
Molecular Cage Reveals Near-Atomic Level Details of Cancer Proteins
Sandwiching wiggly proteins between two other layers allows scientists to get the most detailed images yet of a protein that’s key to the spread of…
Cryo-EM Reveals How “911” Molecule Helps Repair DNA Damage
When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem — a failsafe…
Researchers Use IPET to Capture 3-D Image of an Individual Protein
Researchers at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) produced the first ever 3-D images of an individual protein. Using…
