Scripps Research scientists have identified how the structure of the PI3Kα protein changes in cancer…
Browsing: CryoEM
Cryo-electron microscopy (CryoEM) is a revolutionary technique in structural biology that allows for the visualization of biological molecules in near-native states at atomic resolutions. This method involves rapidly freezing biological samples in a way that preserves their natural structure without the need for dyes or fixatives. The frozen samples are then imaged with an electron microscope, which captures thousands of projections that are computationally combined to produce high-resolution three-dimensional structures of complex proteins, viruses, and other cellular components.
The findings of the study call into question a long-held belief about the way proteins…
University of Virginia Scientists Have Solved a Decades-Old Mystery Researchers from the University of Virginia…
The University of British Columbia researchers have discovered a key vulnerability of major coronavirus variants.…
Cryo-EM snapshots of the solid-electrolyte interphase, or SEI, reveal its natural swollen state and offer…
Combination of nucleic acid nanotechnology and cryo-EM gives unprecedented insights into the structures of large…
Sandwiching wiggly proteins between two other layers allows scientists to get the most detailed images…
Researchers revealed the 911 DNA checkpoint clamp’s role in repairing DNA damage during replication. Using…
Researchers at the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) produced…