DNA Origami Used to Monitor CRISPR Gene Targeting
CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes. To watch CRISPR enzymes respond to different genes,…
Gene Therapy
Winner-Takes-All Synthetic Gene Circuit Process Opens New Pathways to Treat Cancer and Other Diseases
Division of synthetic gene circuit workloads will make therapy more effective. A new process for inserting synthetic gene circuits into host cells, developed by a…
Genetic Mutation Discovery Offers Hope for Effective Autism Drugs
Hebrew University identifies genetic mutation associated with autism, offering hope for effective therapeutics. Recent years have provided substantial research displaying the effect of genetic mutations…
Scientists Develop New Gene Therapy Strategy to Delay Aging and Extend Lifespan
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic…
Neuroscientists Link Brain Cancer to Tissue Healing
Increase of inflammation markers in tumor-initiating cells believed to be a response to brain injury. The healing process that follows a brain injury could spur…
Massive Analysis Reveals New COVID-19 Related Genes – Helpful and Harmful
Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses…
Hundreds of In Vitro Brains Were Grown in a Lab in Italy – Here’s Why
Organoids (In Vitro Brains) to Study Pediatric Brain Tumors A large-scale production of in vitro tumors could make it possible to perform large drug screenings…
Breakthrough in Search For Safer, Easier Way to Deliver Vision-Saving Gene Therapy to The Retina
In experiments with rats, pigs and monkeys, Johns Hopkins Medicine researchers have developed a way to deliver sight-saving gene therapy to the retina. If proved…
Scientists Use Gene Therapy to Successfully Treat Mitochondrial Diseases
Mitochondrial disease is now thought to be the second most commonly diagnosed genetic disease worldwide, and, unfortunately, there are still no proven treatment strategies for…
Gene Therapy Gives Ovarian Cancer Patients Hope
A team of researchers from Harvard and Mass General Hospital has found a gene therapy that delivers a protein which suppresses the development of female…
MIT Researchers Reverse a Rare Liver Disorder in Mice
In a newly published study, MIT researchers show that a new gene-editing technique, known as CRISPR, can reverse a rare liver disorder caused by a…
Telomerase Gene Therapy Extends Mouse Lifespan by 24%
Inducing cells to express telomerase, the enzyme which is supposed to slow down the metabolic clock, has enabled researchers boost the lifespan of mouse by…
Dutch Company Will Start Selling Gene Therapy Treatment in 2013
A Dutch company, uniQure, states that it will start selling the first human gene therapy to be approved in the West by mid-2013. They expect…
New Gene Therapy Has the Ability to Restore Sense of Smell in Mice
A new gene therapy has the ability to fix a defective sense of smell in mice by repairing problems with the cilia on their olfactory…
Researchers Develop Gene Therapy, Promotes Remyelination in a Mouse Model of MS
Researchers at California Institute of Technology (Caltech) believe they have found a way to help the brain replace damaged oligodendrocytes and myelin. By using a…
Gene Therapy Improves Eye Function in Patients
Researchers from the Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia used gene therapy to improve the vision…