A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells….
Bioengineers have repurposed a “non-working” CRISPR system to make a smaller version of the genome engineering tool. Its diminutive size should make it easier to…
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to…
Novel method, developed by McGovern Institute researchers, may lead to safer, more efficient gene therapies. Gene editing, or purposefully changing a gene’s DNA sequence, is…
Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to…
NIH- and USU- led study links ALS to a fat manufacturing gene and maps out a genetic therapy. In a study of 11 medical-mystery patients,…
Researchers from IDC Herzliya and Bar-Ilan University develop a novel software tool to quantify potential CRISPR-induced errors. CRISPR technology allows researchers to edit genomes by…
The CRISPR-based gene editor, C-to-G Base Editor (CGBE), opens up treatment avenues for up to 40 percent of genetic disorders caused by single-nucleotide mutations. A…
A new technology developed by University of Zurich researchers enables the body to produce therapeutic agents on demand at the exact location where they are…
Study shows treatment developed by international team restored immune function in more than 95% of patients in three clinical trials. An experimental form of gene…
Proof-of-principle research shows that genes can be accurately edited in cells throughout the body. Researchers at the University of California San Diego have laid the…
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged. Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized…
For first time, fibroblast-derived model of early embryo will allow extensive study into causes of very early miscarriage and effects of toxins and drugs on…
CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes. To watch CRISPR enzymes respond to different genes,…
Division of synthetic gene circuit workloads will make therapy more effective. A new process for inserting synthetic gene circuits into host cells, developed by a…
Hebrew University identifies genetic mutation associated with autism, offering hope for effective therapeutics. Recent years have provided substantial research displaying the effect of genetic mutations…
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic…
Increase of inflammation markers in tumor-initiating cells believed to be a response to brain injury. The healing process that follows a brain injury could spur…