Glioblastoma is an aggressive and the most common type of primary brain cancer in adults. It originates in the brain’s glial cells, which surround and support the nerve cells. Glioblastoma is known for its rapid growth and tendency to invade surrounding brain tissue, making it particularly difficult to treat effectively. Symptoms can vary depending on the tumor’s location but often include headaches, nausea, seizures, and cognitive or personality changes. Treatment typically involves a combination of surgery, radiation therapy, and chemotherapy, aimed at prolonging survival and improving quality of life. Despite advances in treatment, the prognosis for glioblastoma remains poor, with a median survival time of about 15 to 18 months following diagnosis.
In a first-in-human phase 1 trial in 41 patients with recurrent glioblastoma, an oncolytic virus treatment designed by Brigham researchers extended survival, especially among those…
Glioblastoma, a notoriously hard-to-treat brain cancer, is known for causing cognitive decline as it infiltrates the brain’s neighboring networks. However, this aggressive encroachment could also…
An MIT research team has made a breakthrough in improving the effectiveness of engineered T cells, or chimeric antigen receptor (CAR) T cells, in treating…
A global collaboration directed by a researcher from Stanford Medicine has discovered over 50 genes associated with glioma, a rare brain cancer. While the majority…
A groundbreaking new study introduces a promising therapy for glioblastoma that combines oncolytic virus injections into tumors with intravenous immunotherapy. The treatment, which is safe…
A novel ultrasound technique utilizing microbubbles temporarily opens the blood-brain barrier to treat glioblastoma in humans. One of the biggest challenges in treating glioblastoma, a…
A novel hydrogel developed by Johns Hopkins University researchers cured 100% of mice with aggressive brain cancer by combining anticancer drugs and antibodies to target…
Glioblastoma (GBM) is the most common and deadliest type of brain cancer with a five-year survival rate of only 5%. Researchers at Penn State College…
Findings from a seven-year research project suggests that there could be a new approach to treating one of the most common and devasting forms of…
Results from pre-clinical research show iron-like compound holds promise for treating patients with glioblastoma, an aggressive brain cancer. A novel therapy studied at the Medical…
Researchers from MIT and the Whitehead Institute have discovered a vulnerability of brain cancer cells that could offer a new target for the treatment of…
A new study from scientists at Columbia University Medical Center pinpoints the genetic cause of glioblastoma and found that drugs that target the protein produced…
A new vaccine has been found to extend the life of patients suffering from recurrent glioblastoma multiforme. A phase 2 clinical trial showed that by…