How Helicobacter Pylori Generates An Immune System Blind Spot
The gastric bacterium H. pylori colonizes the stomachs of around half the human population and can lead to the development of gastric cancer. It is…
Immune System
New T Cell Subsets Have Potential to Improve Cellular Therapy for Cancer
Researchers from the Yale Cancer Center have identified that two genes, NR4A1 and ABC transporters, mark a distinct subset of quiescent T cells within human…
Life-Extending Hormone FGF21 Also Protects Against the Loss of Immune Function
New research from Yale University shows that the hormone FGF21, which extends lifespan in mice by 40%, protects against the loss of immune function that…
Yale Examines How Bacteria Might Trigger and Treat Autoimmune Disease
New research from Yale University is exploring how beneficial bacteria that live in the gut might trick the body into an autoimmune reaction known as…
Yale Study Shows Nlrp6 Regulates Intestinal Antiviral Innate Immunity
New research from Yale University shows that the protein known as Nlrp6 plays a key role in the overall immune response that provides immediate defense…
Researchers Reveal How Chronic Inflammation Can Lead to Cancer
New research from MIT reveals how the immune system can create cancerous DNA mutations when fighting off infection. Chronic inflammation caused by disease or exposure…
TH17 Cells Convert from Pro-Inflammatory to Anti-Inflammatory
New research shows that TH17 cells can convert from pro-inflammatory to anti-inflammatory, revealing a possible therapeutic strategy for inflammation-mediated diseases. A type of immune cell…
New Approach Halts the Growth of a Very Aggressive Form of Melanoma
By stimulating both major branches of the immune system, researchers from MIT were able to halt the growth of a very aggressive form of melanoma…
Yale Study Explains How We Live in Harmony With Gut Bacteria
New research from Yale University identifies a strategy that non-harmful gut bacteria employ to preserve this stable relationship with their host during inflammation. Stability in…
Yale Biologists Show Cold Virus Replicates Better at Cooler Temperatures
New research from Yale University shows that the common cold virus can reproduce itself more efficiently in cooler temperatures, reaffirming the popular, yet contested, notion…
Max Planck Researchers Discover New Weapon of the Immune System
Scientists have identified a previously unknown component of the immune system, discovering that bacterial virulence factors can not only be neutralized by antibodies, but they…
Chitinase 3-like-1, A Key to Fighting Pneumonia
While working with mice, scientists at Yale University found that the protein Chitinase 3-like-1 (Chi3l1) was crucial in regulating the immune response to Streptococcus pneumonia,…
Study Links Immune Irregularities and Autism
A newly published study from scientists at Caltech suggests that specific changes in an overactive immune system can contribute to autism-like behaviors in mice and…
Nanoparticle Delivers a Combination of Therapeutic Agents to Tumor Sites
Developed by a team of scientists at Yale, a new biodegradable nanoparticle, called a nanogel, delivers a combination of two therapeutic agents to tumor sites,…
Microbial Life Lining Our GI Tracts Has Coevolved With Us
A new study from the Harvard Medical School suggests that the superabundant microbes lining our gastrointestinal tract are ultimately our evolutionary partners, shedding light on…
Understanding the Internal Process that Makes Salmonella Dangerous
A recently published study examines why Salmonella becomes dangerously virulent. While examining signals from outside the bacteria, they found that changes in the level of…
Increasing Th17 Cells in the Gut May Improve the Control of HIV Growth
A new study from a team of microbiologists and immunologists suggests that treatment aimed at increasing Th17 cells in the gut may improve the control…
New Antibody Drug Boosts the Immune System’s Capacity to Fight Cancer
A new study using antibody drug BMS-936558 (MDX-1106, anti-PD-1), resulted tumor shrinkage of at least 30 percent in 18 percent of the lung cancer patients,…