Chemists Discover Unexpected Synergy Between Two Cancer Drugs
A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become…
A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become…
Injectable material made of nanoscale particles can deliver arthritis drugs throughout cartilage. Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million…
Researchers at The University of Texas at Arlington have found a potential new pathway to regulate immune response and potentially control inflammatory diseases of the…
Schizophrenia, a brain disorder that produces hallucinations, delusions, and cognitive impairments, usually strikes during adolescence or young adulthood. While some signs can suggest that a…
A simple modification of a DNA base in small areas of the genome may explain why glioblastoma tumors are so deadly, researchers at Yale and…
Patients with blood cancers such as leukemia and lymphoma are often treated by irradiating their bone marrow to destroy the diseased cells. After the treatment,…
More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores…
Mitochondrial disease is now thought to be the second most commonly diagnosed genetic disease worldwide, and, unfortunately, there are still no proven treatment strategies for…
Every skin cell on the human body is replaced weekly, with stem cells generating billions of specialized progeny that engage in an orchestrated scramble to…
A new auto-commentary published in SLAS Technology looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can…
In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins—proverbial…
A three-dimensional map showing an actin filament (blue) bound to a fragment of the cross-linking protein, filamin A (green). For human cells to form and…
Uncovered details of a molecular pathway in cancer cells could lead to improved treatment. Targeting a pathway that controls the movement of mitochondria, the powerhouses…
A study by a Massachusetts General Hospital (MGH) research team finds that neurogenesis — inducing the production of new neurons — in the brain structure…
Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common…
One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain…
Researchers from the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Jonsson Comprehensive Cancer Center have discovered an important…
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory…