Scientists Have Identified Over 5000 High-Risk Cancer Gene Variants
Researchers have pinpointed specific variants in a gene that significantly raise the likelihood of developing various cancer types. This discovery has the potential to enhance…
The Wellcome Trust Sanger Institute is a prominent genomic research center located in Hinxton, England, part of the Wellcome Genome Campus. It was established in 1992 and named after Frederick Sanger, a two-time Nobel laureate in chemistry renowned for his work on DNA sequencing. The institute plays a significant role in the fields of genomics and genetic research, particularly noted for its substantial contributions to the Human Genome Project. Its research focuses on understanding the role of genetics in health and disease, studying a wide range of topics including human genetics, pathogen genetics, and cellular genetics. The Sanger Institute is known for its use of large-scale genomic data to explore the biological processes involved in the development of diseases and the therapeutic implications of these findings.
Researchers have pinpointed specific variants in a gene that significantly raise the likelihood of developing various cancer types. This discovery has the potential to enhance…
A new project unites world-leading experts in quantum computing and genomics to develop new methods and algorithms to process biological data. Researchers aim to harness…
The first detailed cell atlas of aging human muscle uncovers the complex genetic and cellular activities involved in muscle degeneration and identifies ways to mitigate…
Researchers have studied the escalation of antibiotic resistance in the UK and Norway over the past two decades, highlighting that the surge in resistance is…
A groundbreaking study reveals how inherited genetic variants contribute to the development of rare blood cancer, offering insights for disease prediction and treatment strategies. Large-scale…
Scientists reveal unprecedented insights into human limb development, including the many intricate processes that govern their formation. Human fingers and toes do not grow outward;…
New study reveals drivers of rare cancer and provides a possible alternative solution to surgery. The genetic code of a rare form of kidney cancer,…
Researchers from UCL, Great Ormond Street Hospital, and the Wellcome Sanger Institute have unveiled findings that shed light on why certain children experience extended remission…
Using a newly developed tool called GASPACHO, scientists have discovered a gene variant linked to increased susceptibility to COVID-19. The tool allows them to track…
Researchers have discovered that a specific virulent E. coli subset, K1, predates previous estimations by around 500 years and 25% of current E. coli strains…
Researchers at the Wellcome Sanger Institute have developed a new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the…
A new explanation for aging has been developed by researchers who have shown that genetic abnormalities that develop gradually over a lifetime cause substantial alterations…
Scientists have traced the cause of increased numbers of mutations in children to a higher rate of random mutations in sperm cells of the biological…
Quantity of mutations acquired is similar over the lifetime of 16 species, despite vast differences in lifespan and body mass. The first study to evaluate…
Research shows that children’s stronger innate immune response helps them fend off SARS-CoV-2 more effectively than adults, who experience slower immune reactions allowing the virus…
Modern hospitals and antibiotic treatment alone did not create all the antibiotic-resistant strains of bacteria we see today. Instead, selection pressures from before the widespread…
Researchers have sequenced the genome of an 11,000-year-old dog cancer, revealing its secrets and origin. Scientists have sequenced the genome of the world’s oldest continuously…
Scientists from the Wellcome Trust Sanger Institute have identified the majority of the mutational signatures that explain the genetic development and history of cancers in…