The cause of more than 40 years of unexplained pain was revealed to be a rare under-fingernail tumor.
In a case report being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC) in Milan, Italy, doctors from France and Armenia describe a 58-year-old woman who experienced severe, unexplained finger pain for more than 40 years while knitting.
The lady was found to have a rare benign growth beneath her fingernail. The pain was also brought on by cold weather. The tumor was successfully removed.
The patient, a right-handed person, visited the Wigmore Clinic in Yerevan, Armenia in October 2021 because she had a terrible shooting and scorching pain in her right index finger that had been brought on by knitting.
She also had finger pain during cold temperatures, along with pins and needles in her right lower arm and shoulder. The lady, who had never previously had a finger injury, has been experiencing this pattern of symptoms for more than 40 years. Reynaud’s disease and a neuroma were among the other conditions for which she had visited several doctors and received unsuccessful treatment.
A comprehensive French-Armenian examination of the lady, who was from Armenia, was conducted at the Wigmore Clinic by a team organized by the Hospices Civils de Lyon, the second-largest university hospital in France. As part of a medical program established by the French government in the wake of the 2020 Artsakh conflict, the Hospices Civils de Lyon is one of three French university hospitals offering medical training in Armenia.
The multidisciplinary team included a pain specialist, hand surgeon, physiotherapist, bone and joint infection disease specialist, microbiologist, neurologist, and radiologist.
A physical examination revealed that putting pressure on her nail, stroking the edge of her nail, applying ice to her hand, and holding her hand downwards all produced the same pattern of pain as knitting.
Raising and holding up her arm provided almost instant pain relief. Tests showed she had normal levels of pain sensitivity. A small section of the nail on her right index finger was slightly bulbous, darker than the surrounding nail, and faintly purple.
This deformity, in combination with a slight scalloping of the surface of the bone under the nail (revealed by X-ray) and a small, dense mass with no blood vessels inside, along with an adjacent bone defect (both revealed by ultrasound), suggested the patient had a glomus tumor.
Glomus tumors are rare, normally benign, soft tissue tumors. More common in middle-aged women than in other groups, they account for around 2% of all soft tissue tumors.
The majority (75%) are found under a fingernail or toenail. They can develop in any part of the body, however, and have been found on the penis and inside the stomach. Normally benign, they can in rare cases, become malignant and spread to multiple sites throughout the body.
Examination of the growth under the woman’s nail, after removal in a 30-minute operation in late October 2021, confirmed it to be a benign glomus tumor, 5mm in size.
The operation took place in the Hand Surgery Department of the National Burn Centre in Yerevan and was performed by an Armenian team.
“Glomus tumors are uncommon and while hand and plastic surgeons are familiar with them, they may present a puzzle for other specialists,” says pain specialist and anaesthesiologist Dr. Mikhail Dziadzko, of the Department of Anaesthesiology & Pain Medicine, Hopital de la Croix Rousse, Lyon, who was part of the French-Armenian multi-disciplinary team.
“This patient had a 5mm tumor which had been growing slowly for more than 40 years. Her quality of life was affected not only by painful sensations during particular gestures and cold weather but also by constant anticipation of the pain and frustration over the inability to solve the problem over the decades.”
He continues, “A surgeon was able to remove the tumor in a 30-minute procedure using local anesthesia. No particular care was required after surgery, other than standard painkillers such as paracetamol and non-steroid anti-inflammatory drugs (NSAIDs), which were prescribed for a short period of time. There were no complications of surgery and the patient’s recovery was uneventful. When seen at a follow-up appointment three months after her operation, she said she no longer had any pain in her finger. She was able to return to her hobby – knitting – and almost forget these 40 years of suffering.”
Dr. Dziadzko adds: “The origin of a patient’s pain isn’t always clear. However, in a puzzling situation, a multidisciplinary approach involving different specialists, such as anesthesiologists, radiologists, and surgeons, will almost always help find a solution.”