Arthritis is a common condition characterized by inflammation of one or more joints, leading to pain and stiffness that typically worsen with age. There are several types of arthritis, with osteoarthritis (OA) and rheumatoid arthritis (RA) being the most prevalent. Osteoarthritis involves wear-and-tear damage to joint’s cartilage, which is the cushioning material at the ends of bones. As the cartilage wears down, bone grinds directly on bone, causing pain and restricted movement. Rheumatoid arthritis, on the other hand, is an autoimmune disorder where the body’s immune system attacks the lining of the joint capsule, a tough membrane that encloses all the joint parts. This inflammation can eventually lead to joint erosion and may damage other parts of the body as well.
Dr. Melissa Grunlan is creating synthetic plugs to help patients with chronic knee pain or disabilities, potentially eliminating the need for total knee replacements. Osteochondral…
Early detection of knee osteoarthritis could lead to therapies that slow progression and restore joint health. A blood test successfully predicted knee osteoarthritis at least…
Scientists at Scripps Research have developed atomic-level structural models of enzymes linked to autoimmune and inflammatory conditions, such as lupus and Alzheimer’s disease. When nucleic…
Tryptophan is needed for our survival, yet bacteria can convert it into a chemical that causes inflammation. A researcher from the CU Department of Medicine…
A new study reveals that RvT4 improves macrophage function to fight atherosclerosis in rheumatoid arthritis, suggesting new treatment pathways. Scientists from Queen Mary University of…
A new study reveals that a commonly prescribed rheumatoid arthritis drug may also suppress the development of type 1 diabetes. Researchers at St Vincent’s Institute…
A new study published in the journal Rheumatology reveals that JAK inhibitors, commonly used to treat arthritis patients, are indeed effective. Despite initial concerns about their…
An affordable drug, commonly used for treating inflammatory joint conditions, has shown promise as a treatment for painful hand osteoarthritis, according to a study led…
Existing therapies for osteoarthritis focus on symptom relief instead of tackling the root cause of the disease. However, recent research conducted by the University of…
The findings strengthen the theory that childhood infections influence ankylosing spondylitis development. A large study published in the open-access journal RMD Open reveals that having…
Advancements in understanding the disease could bring about a paradigm shift. For a long time, osteoarthritis was believed to stem from wear and tear in…
Scientists from the Keck School of Medicine of USC identify key cells involved in the process of cartilage regeneration in lizards—a discovery that could offer…
Research undertaken by scholars at Swansea University has discovered that canagliflozin, a drug commonly used to treat type 2 diabetes, may also have potential therapeutic…
Recruiting osteoarthritis patients with a lot of pain to clinical studies, may give incorrect results if the researcher does account for the natural variation in…
A team of researchers at OU has discovered a protein complex that plays a crucial role in the development of rheumatoid arthritis. Furthermore, their findings…
A researcher at Rice University discovers a critical piece of information in discarded data that redirects their research in the right direction. Regular dental check-ups…
What goes wrong in our bodies during the progression of an inflammatory disease? Scientists at the School of Biochemistry and Immunology in the Trinity Biomedical…
According to a recent study, it is estimated that approximately 13,200 men and 2,300 women over the age of 50 in the United States have…