Scientists Reveal Catalog of Human Genetic Variation
Newly published research details the effects of human genetic variation, finding that each person possesses on average about 150 variants capable of disabling genes. A…
genetics
Bioengineers Develop a New System for Human Genome Editing
A team of scientists from MIT, Harvard and Wageningen University have developed a new system for human genome editing that has potential to increase the…
B12 Identified as a Key Part of Photoreceptor Proteins
A team of scientists has discovered and mapped a light-sensing protein that uses vitamin B12 to perform key functions, including gene regulation. The result, derived…
Scientists Report a Major Breakthrough in Alzheimer’s Disease
New research sheds light on a fundamental mechanism underlying the development of Alzheimer’s disease and could lead to new forms of therapy people with the…
Harvard Researchers Explain the Reason for Genetic Obesity
Researchers from Harvard Medical School and MIT reeval a genetic circuit that controls whether our bodies burn or store fat. Like many other conditions, obesity…
Researchers Discover Pathway That Controls Metabolism
By analyzing the cellular circuitry underlying the strongest genetic association with obesity, a team of researchers from MIT and Harvard Medical School have unveiled a…
International Research Collaboration Reveals Mutations in DCHS1 Cause Mitral Valve Prolapse
Researchers reveal that mutations of the DCHS1 gene cause a common form of mitral valve prolapse. An international research collaboration led by Harvard Medical School…
New Biosensors Turn Bacteria Into a Source of Natural Energy
New biosensors enable complex genetic reprogramming of common bacteria like E. coli. The process could be leveraged for sustainable biomanufacturing, using the metabolic processes of…
Newly Developed Simple Protein Plays Active Role in Cellular Function
Scientists from Yale University have created a synthetic protein that is active, despite its simplicity. Yale scientists have developed simple new proteins almost devoid of…
Yale Scientists Reveal ‘Major Player’ in Skin Cancer Genes
Researchers from Yale University have confirmed that a gene known as NF1 is a “major player” in the development of skin cancer. A multidisciplinary team…
CCNE1 Gene Turns Back Cellular Clock
Yale researchers have discovered a gene that turns back the cellular clock, greatly aiding the reprogramming of mature cells. An exhaustive analysis of factors that…
Nanoparticles Deliver PNA Molecules to Correct Mutation in Cystic Fibrosis
New research details how a team of scientists delivered peptide nucleic acids and donor DNA via microscopic nanoparticles to successfully corrected the most common mutation…
Scientists Discover a Gene for Brain Size
A team of researchers has identified for the first time a gene (ARHGAP11B) that is only present in humans and contributes to the reproduction of…
Researchers Uncover Genetic Trigger for Immune Response
Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response, showing a new source of inflammation that could promote common diseases…
A Link between Inflammation and Cancer
New research from MIT reveals a link between inflammation and cancer, showing that the timing of inflammation determines whether potentially cancerous mutations may arise. A…
The Role of Genetics Varies Over Time
New research from Yale University shows that the effect of genes may depend on the total, historical environment in which the researcher and subject are…
Gene-Editing System Allows Rapid, Large-Scale Studies of Gene Function
Using a gene-editing system that was originally developed to delete specific genes, researchers from MIT developed a new technique to reliably turn on any gene…
Research Reveals New Strategy to Control Cellular Identity and Fate
Newly published research suggests a new strategy to control cellular identity and fate, revealing that depleting or knocking out a chemical tag on RNA keeps…