Biologists Develop Breakthrough RNA-Based Therapy to Target West Nile Virus
A Yale-led research team developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus. The innovative approach reduced…
Pathology
Shining Molecules Detect Tau Pathology in Alzheimer’s Disease
Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain. They…
Monkeys and Humans Share Same Signs of Alzheimer’s
Very old rhesus monkeys exhibit similar patterns of brain pathology as human Alzheimer’s patients, researchers report in the journal Alzheimer’s & Dementia: The Journal of…
Wolf-Sized Prehistoric Otter Had a Surprisingly Powerful Bite
A newly published study reveals that a massive, wolf-sized otter that lived about 6 million years ago may have been a dominant predator in its…
New Study Reveals Why Some People Develop Progressive Multiple Sclerosis
A team of researchers has uncovered two closely related cytokines — molecules involved in cell communication and movement — that may explain why some people…
Researchers Find Antibody That ‘Neutralizes’ Zika Virus
A team of researchers has isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. The antibody, called…
Yale Researchers Reveal Genes Behind Aggressive Ovarian and Endometrial Cancers
Researchers from Yale University have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas, pointing the way to possible new treatments. The findings…
Study Reveals a Promising New Target to Treat Type 2 Diabetes
Scientists at Yale University reveal promising new target for drugs to treat type 2 diabetes. When the body’s cells don’t respond normally to insulin —…
Yale Study Shows Gut Bacteria Aggressively Protect Their Territory
A newly published study from Yale University details how human gut bacteria take on many tasks crucial to health. Bacterially speaking, it gets very crowded…
Yale Researchers Identify Gene That Regulates the Growth of Melanoma
New research from Yale University identifies a gene in melanoma that can dramatically affect the growth of the disease. The findings, published in the journal…
Study Shows Amateur Contact Sports Increase Risk of Degenerative Disorder
Past evidence has shown that professional football players are susceptible to a progressive degenerative disease, chronic traumatic encephalopathy (CTE), which is caused by repetitive brain…
Genetically Reducing AMPK Activity May Prevent Hereditary Hearing Loss
New research from Yale University reveals that genetically reducing AMPK activity delays hereditary hearing loss in mice. Hereditary hearing loss can worsen over time and…
Scientists Produce Photoreceptors from Embryonic Stem Cells
By producing photoreceptors from human embryonic stem cells, researchers from the University of Montreal have taken a major step forward in the fight against age-related…
Yale Scientists Reveal ‘Major Player’ in Skin Cancer Genes
Researchers from Yale University have confirmed that a gene known as NF1 is a “major player” in the development of skin cancer. A multidisciplinary team…
Researchers Uncover Genetic Trigger for Immune Response
Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response, showing a new source of inflammation that could promote common diseases…
New Method for Detecting Unwanted DNA Breaks in Human Cells
Researchers at the Harvard Medical School have developed a new method for detecting unwanted DNA breaks across the entire genome of human cells induced by…
Scientists Uncover a Pathway for Silencing Tumor Suppressor Genes
Researchers have identified a RAS-regulated pathway that initiates and maintains the epigenetic silencing of tumor suppressor genes in mice, a finding that may help provide…
Cancer Scientists Prove Long-Standing Theory on How Cancer Spreads
A newly published study shows that white blood cells and a cancer cells can fuse and initiate a tumor, providing the first proof in humans…