Flu Mutation Study: Universal Flu Vaccine May Be More Challenging Than Expected
Many flu strains may be capable of mutating to escape universal-vaccine antibodies. Some common strains of influenza have the potential to mutate to evade broad-acting…
Scripps Research Institute News
“Silent” Carriers: Extraordinary Percentage of SARS-CoV-2 Coronavirus Infections May Be Asymptomatic
Analysis of data from 16 groups of COVID-19 patients suggest ‘silent’ carriers may exacerbate efforts to stop spread of the disease. An extraordinary percentage of…
Century-Old Scientific Debate Settled: Anesthesia’s Effect on Consciousness Solved
Billiard-like break shot to cell-membrane structures triggers brain’s loss of consciousness from anesthesia, scientists find. Surgery would be inconceivable without general anesthesia, so it may…
Your Computer Can Help Scientists Searching for COVID-19 Treatments
IBM’s World Community Grid hosts Scripps Research project to virtually screen chemical compounds that might help fight COVID-19. Under a collaboration between IBM and Scripps…
Potential Vulnerability of COVID-19 Coronavirus Discovered From an Antibody Against SARS
A Scripps Research study reveals a likely site of vulnerability on the SARS-CoV-2 virus. An antibody recovered from a survivor of the SARS epidemic in…
No Evidence COVID-19 Coronavirus Was Genetically Engineered in a Lab – Epidemic Has a Natural Origin
Scripps Research’s analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or…
Unexpected Approach Is Chemistry ‘Warp Drive’ for Creating Better Synthetic Molecules for Medicine
An unexpected approach blurs the line between synthetic drug molecules and natural products, with the goal of achieving higher quality compounds for medicines. In a…
Recently Discovered Protein Has Important Role in Obesity and Diabetes
The little-known protein is normally abundant in fat; without it, the body struggles to manage glucose and insulin. With unexpected findings about a protein that’s…
New Medicines & ‘Green’ Insecticides Possible With Efficient Synthesis of Ginkgo Compound
New method offers an easy route for making bilobalide and related compounds so scientists can explore their potential uses as drugs and pesticides. Chemists at…
How Did Cells Originally Form Billions of Years Ago? Scientists Identify Molecule That May Be Key to Emergence of Life on Earth.
Compounds called cyclophospholipids would have held up against the planet’s harsh conditions, helping the first cells form and proliferate. Researchers must dissect the building blocks…
Safer Pain Medications Possible After Discovery of Anti-Opioid Pathway
A team at Scripps Research in Florida has discovered a biological system that manages cells’ response to opioid drug exposure. The unexpected discovery offers new…
Chemists Reveal New Theory For How Life On Earth May Have Begun
Chemists at The Scripps Research Institute (TSRI) have developed a fascinating new theory for how life on Earth may have begun. Their experiments, described today…
Chemists Find Potential “Missing Link” in Origins-of-life on Earth
A team of researchers at The Scripps Research Institute (TSRI) have discovered a compound that may have been a crucial factor in the origins of…
New Findings Provide a Design for an HIV Vaccine Germline-Targeting Immunogen
A team of researchers has found HIV-1 broadly neutralizing antibody precursor B cells that are present in most people, and has described the design of…
New Anti-HIV Candidate Blocks Every Strain of HIV-1, HIV-2 and SIV
In a new study, researchers show that a new drug candidate blocks every strain of HIV-1, HIV-2, and SIV that has been isolated from humans…
Scientists Turn Diseased Cells Against Themselves
Scientists from the Scripps Research Institute have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that could potentially treat…
Scientists Engineer First Living Organism with an Expanded Genetic Alphabet
A newly published study details how researchers at The Scripps Research Institute were able to create the first living organism with an expanded genetic alphabet….
Drug Candidate SR9009 Increases Exercise Endurance
A new drug candidate, SR9009, has been shown to significantly increase exercise endurance in animal models. Researchers believe these findings may lead to better treatments…