Genetics News

MIT Researchers Reverse a Rare Liver Disorder in Mice

April 3, 2014

1 Comment

In a newly published study, MIT researchers show that a new gene-editing technique, known as CRISPR, can reverse a rare liver disorder caused by a single genetic mutation. Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, […]

Continue reading...

How Genetic Research Can Help People Colonize Other Planets

March 28, 2014

0 Comments

A recently held symposium by the HMS Department of Genetics asked experts to consider how genetic research can help people colonize other planets. If you haven’t thought about reworking the human genome so people can colonize other planets, don’t worry. Plenty of people are on it. Scientists of many stripes have been figuring out what […]

Continue reading...

Deleting a Single Gene Reduces Fat Mass and Extends Lifespan of Mice by 20%

March 26, 2014

1 Comment

Researchers discover that mice without the FAT10 gene have an elevated metabolic rate, burn fat as fuel, exhibit reduced glucose and insulin levels, and age more slowly than normal mice. By deleting a single gene, researchers at Yale University were able to dramatically reduce fat mass in mice while expanding their lifespan by 20%. The […]

Continue reading...

Yale Researchers Identify a Key Link between Tumors and Healthy Tissue

March 21, 2014

2 Comments

Researchers from the Yale School of Medicine have discovered a key link between tumors and healthy tissue, revealing a potential mechanism used by cancer cells to recruit healthy cells to promote tumor growth. The delicate balance between development of normal tissue and tumors depends in part upon a key molecular switch within cells, Yale School […]

Continue reading...

Naturally Occurring Molecule Enhances Defense Mechanisms Against Neurodegenerative Diseases

March 14, 2014

0 Comments

Scientists have discovered that a substance called N-acetylglucosamine has the ability to enhance defense mechanisms against neurodegenerative diseases, clear toxic protein aggregates and extend life span. Scientists at the Max Planck Institute for Biology of Aging in Cologne have found that a naturally occurring molecule has the ability to enhance defense mechanisms against neurodegenerative diseases. […]

Continue reading...

New Study Shows that IRX3 Is Likely the “Fat Gene”

March 13, 2014

0 Comments

A new study shows that the IRX3 gene controls body mass and regulates body composition, and appears to be the functional obesity gene. Mutations within the gene FTO have been implicated as the strongest genetic determinant of obesity risk in humans, but the mechanism behind this link remained unknown. Now, an international team of scientists […]

Continue reading...

Yale Researchers Find Hope for Safe and Novel Painkillers from Tarantula Venom

February 17, 2014

0 Comments

Yale researchers find new hope for safe and novel painkillers from the venom of the Peruvian green velvet tarantula. Screening more than 100 spider toxins, Yale researchers identified a protein from the venom of the Peruvian green velvet tarantula that blunts activity in pain-transmitting neurons. The findings, reported in the March 3 issue of the […]

Continue reading...

Gene Linking Brain Structure to Intelligence Identified

February 12, 2014

1 Comment

An international team of scientists has identified a gene linking brain structure to intelligence, finding that teenagers carrying a particular gene variant had a thinner cortex in the left cerebral hemisphere and performed less well on tests for intellectual ability. For the first time, scientists at King’s College London have identified a gene linking the […]

Continue reading...

Study Shows Root of Birth Defects Grounded in Early Embryonic Development

November 14, 2013

1 Comment

In a newly published study, Yale researchers detail a genetic mutation associated with congenital heart disease that disrupts a key signaling mechanism and leads to a form of heart defect associated with misalignment of major organs. The search for the cause of devastating birth defects has led Yale School of Medicine researchers to a key […]

Continue reading...

Rudimentary Form of Life Sidesteps Normal Replication Processes

November 4, 2013

1 Comment

Researchers from the University of Nottingham have shown that in some organisms the genetic switches that control DNA replication are unnecessary and that cells will actually grow faster when the replication origins are not present. A rudimentary form of life that is found in some of the harshest environments on earth is able to sidestep […]

Continue reading...

Hair Restoration Method Generates New Human Hair Growth

October 21, 2013

3 Comments

A new hair restoration method developed by researchers at Columbia University Medical Center is the first to induce new human hair growth. New York, New York — Researchers at Columbia University Medical Center (CUMC) have devised a hair restoration method that can generate new human hair growth, rather than simply redistribute hair from one part […]

Continue reading...

New Genome Analysis Reveals Dozens of Cancer Triggers

October 4, 2013

1 Comment

A new analysis of little-explored regions of the human genome has revealed dozens of cancer triggers. A massive data analysis of natural genetic variants in humans and variants in cancer tumors has implicated dozens of mutations in the development of breast and prostate cancer, a Yale-led team has found. The newly discovered mutations are in […]

Continue reading...