Brain tumors are abnormal growths of cells in the brain or central spinal canal. They can be classified as either benign (non-cancerous) or malignant (cancerous), with the latter having the potential to grow aggressively and invade surrounding tissue. Brain tumors can originate in the brain (primary tumors) or spread from other parts of the body (metastatic or secondary tumors). Symptoms of brain tumors vary depending on the tumor’s size, type, and location, but may include headaches, seizures, vision or hearing problems, behavioral changes, and cognitive impairments. Treatment options depend on the tumor’s characteristics and may involve surgery, radiation therapy, chemotherapy, or a combination of these. Advances in medical imaging and neurosurgical techniques have improved the diagnosis and treatment of brain tumors, enhancing outcomes and quality of life for many patients. Nonetheless, the treatment of brain tumors poses significant challenges due to the critical and sensitive nature of the brain tissue involved.
The use of poly-ICLC in combination with a dendritic cell-based immunotherapy vaccine shows promise as a treatment for patients with deadly brain cancer. Researchers at…
This is the first study to assess the risk associated with widely used progestogens. Extended use of certain progestogen hormone medications has been linked to…
The scientists found that vaccine strains of the Zika virus eradicate brain tumor cells while sparing healthy ones. Scientists from Duke-NUS Medical School (Duke-NUS) have…
A new microscopy technique that enables high-resolution imaging could one day help doctors diagnose and treat brain tumors. Using a novel microscopy technique, MIT and…
A simple blood test could help diagnose patients with the deadliest form of brain cancer, sparing them from undergoing invasive, highly risky surgery. In a…
A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells. An important part of choosing the most suitable cancer therapy…
Researchers from the Princess Máxima Center and the Hubrecht Institute have developed advanced brain organoids that closely resemble the human cortex. These organoids, named Expanded…
In a first-in-human phase 1 trial in 41 patients with recurrent glioblastoma, an oncolytic virus treatment designed by Brigham researchers extended survival, especially among those…
Scientists have discovered innovative new method to target and kill cancer cells in hard-to-treat brain tumors using electrically charged molecules to trigger self-destruction, that could…
Clinical studies reveal extended survival in diffuse midline glioma patients receiving ONC201 treatment; research also explains the underlying mechanism of the drug’s success. For the…
Glioblastoma, a notoriously hard-to-treat brain cancer, is known for causing cognitive decline as it infiltrates the brain’s neighboring networks. However, this aggressive encroachment could also…
A global collaboration directed by a researcher from Stanford Medicine has discovered over 50 genes associated with glioma, a rare brain cancer. While the majority…
Study is the first clinical trial analyzing a targeted therapy specifically developed to treat brain tumors. A targeted therapy drug called vorasidenib had positive results…
Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models. Brigham and Women’s…
A groundbreaking new study introduces a promising therapy for glioblastoma that combines oncolytic virus injections into tumors with intravenous immunotherapy. The treatment, which is safe…
A novel ultrasound technique utilizing microbubbles temporarily opens the blood-brain barrier to treat glioblastoma in humans. One of the biggest challenges in treating glioblastoma, a…
A novel hydrogel developed by Johns Hopkins University researchers cured 100% of mice with aggressive brain cancer by combining anticancer drugs and antibodies to target…
Researchers found that a derivative of the natural compound indirubin offers a new approach to treating glioblastoma in mice, which will inform future research in…