The Missing Piece in Chronic Pain Puzzle? Novel Protein Function Discovered
Researchers in Gary Lewin’s lab at the Max Delbrück Center have pinpointed an ion channel that plays a role in chronic pain, offering a new…
Chronic pain is a complex and persistent condition that lasts for months or years beyond the usual recovery period, or is associated with a chronic health condition, such as arthritis. Unlike acute pain, which serves as a normal response to an injury or illness, chronic pain can continue without a clear cause, significantly affecting an individual’s quality of life and functionality. The management of chronic pain involves a multidisciplinary approach, including physical therapy, medications such as NSAIDs (non-steroidal anti-inflammatory drugs) or opioids, psychological counseling, and lifestyle modifications like exercise and stress management. Techniques such as nerve blocks, acupuncture, and, in some cases, surgical interventions may also be used. Understanding and treating chronic pain can be challenging due to its subjective nature and the variety of factors that can influence it, including emotional and environmental factors.
Researchers in Gary Lewin’s lab at the Max Delbrück Center have pinpointed an ion channel that plays a role in chronic pain, offering a new…
A team of researchers from the Institute for Bioengineering of Catalonia (IBEC) has developed light-activated derivatives of the anti-epileptic drug carbamazepine to treat neuropathic pain….
New research has revealed that regular walking significantly extended pain-free periods for adults with low back pain, proving its effectiveness and affordability as a preventive…
Menthol detection predates the sensation of cold, indicating separate activation mechanisms that can be distinguished. This differentiation opens possibilities for novel pain treatments that avoid…
Researchers have discovered sex-specific differences in the nerve cells that generate pain, paving the way for personalized pain management treatments based on patient sex. Research…
Dr. Melissa Grunlan is creating synthetic plugs to help patients with chronic knee pain or disabilities, potentially eliminating the need for total knee replacements. Osteochondral…
Researchers at the Comprehensive Center for Pain & Addiction conducted tests on five terpenes, finding promising results in their pain-relief capabilities. A study from the…
The study indicates that nanocarriers loaded with DNA may serve as alternatives to opioids. Recent research demonstrates that gene therapy delivered by nanocarriers can effectively…
Cambridge researchers have created flexible, minimally invasive devices that can wrap around nerves, offering new ways to treat neurological conditions and control prosthetics. Researchers have…
New research indicates that the development of chronic musculoskeletal pain may be influenced by factors such as socioeconomic status, fear of movement, smoking, and weaker…
JAMA Network Open commentary focuses on the relationship of pain, depression, and anxiety. Chronic pain is often accompanied by depression and anxiety. In an invited…
A study supported by the NIH and conducted by Worcester Polytechnic Institute aims to leverage artificial intelligence in identifying effective mindfulness-based treatments for chronic lower…
Explaining why certain individuals with specific joint deformities experience symptoms, whereas others do not. With the array of advanced imaging technologies at their disposal, healthcare…
The first-ever clinical trial focuses on precision medicine specifically for older adults, a group often overlooked in musculoskeletal research. Two decades ago, when Gregory Hicks…
Globally, low back pain significantly contributes to disability, impacting over 570 million individuals. In the United States alone, between 1996 and 2016, healthcare expenses related…
Researchers have discovered a small molecule capable of inhibiting four types of pain in preclinical studies. A new study led by the Pain Research Center…
The results of a recent trial suggest that the use of this treatment needs to be reevaluated. A clinical trial recently published in The BMJ…
Scientists have a ‘Suicidal’ mechanism discovered in ion channel receptors which enables the sensing of heat and pain. The ability to accurately detect heat and…