A study from the Hackett group at EMBL Rome led to the development of a…
Browsing: Epigenetics
Epigenetics is the study of changes in gene expression that do not involve alterations to the underlying DNA sequence — a change in phenotype without a change in genotype. These changes can result from external or environmental factors that switch genes on and off and affect how cells read genes. Epigenetic changes can be natural and crucial for development, but they can also be influenced by several factors including age, the environment/lifestyle, and disease state. Epigenetic modifications are reversible and are implemented via mechanisms such as DNA methylation, histone modification, and RNA-associated silencing. Research in epigenetics has profound implications for understanding complex processes like development, aging, and the pathology of diseases like cancer. Increasingly, epigenetics is considered a key factor in the heritability of lifestyle diseases such as obesity and diabetes, potentially bridging the gap between genetic predisposition and environmental influences.
A new study reveals that cancer can develop purely from epigenetic changes, challenging the conventional…
A recent study conducted by Lund University researchers, and published in Nature Communications, suggests that…
Research indicates smoking’s prolonged influence on immunity, linked to epigenetic changes, persists even after quitting.…
Research highlights the critical role of endothelial cells and DNA methylation in cancer metastasis, pointing…
Epigenetics involves chemical processes that regulate gene activity, enabling our cells, tissues, and organs to…
Researchers at the Indiana University School of Medicine, at the school’s South Bend regional campus,…
A team of European researchers has developed an innovative test that accurately measures biological aging…
Two Eötvös Loránd University researchers have made an exciting breakthrough in understanding how we age.…
Every cell synthesizes its own proteins by interpreting the genetic information in its genes. Mutations,…
Researchers have discovered molecular markers in cheek cells that could predict obesity, potentially allowing for…
Chromosomal instability in cancer leads to micronuclei formation, which disrupts epigenetic regulation upon rupture, contributing…
MIT engineers’ new technique analyzes the 3D organization of the genome at a resolution 100…
In both preclinical models and human subjects, stress caused by surgery, pregnancy, and severe COVID-19…
Obesity caused by a high-fat diet leads to lasting immune changes, increasing the risk of…
Johns Hopkins University researchers have discovered that the protein histone H3 in roundworm chromosomes influences…
An 8-week methylation-supportive diet and lifestyle program was found to significantly decrease biological age in…
Evidence suggests that exercise creates a molecular profile in muscle that is consistent with the…