AI model crossNN identifies over 170 tumor types with high accuracy using genetic material, offering…
Browsing: Epigenetics
Epigenetics is the study of changes in gene expression that do not involve alterations to the underlying DNA sequence — a change in phenotype without a change in genotype. These changes can result from external or environmental factors that switch genes on and off and affect how cells read genes. Epigenetic changes can be natural and crucial for development, but they can also be influenced by several factors including age, the environment/lifestyle, and disease state. Epigenetic modifications are reversible and are implemented via mechanisms such as DNA methylation, histone modification, and RNA-associated silencing. Research in epigenetics has profound implications for understanding complex processes like development, aging, and the pathology of diseases like cancer. Increasingly, epigenetics is considered a key factor in the heritability of lifestyle diseases such as obesity and diabetes, potentially bridging the gap between genetic predisposition and environmental influences.
Why do so many people in one Italian town live past 100 in excellent health?…
The scientists state that epigenetic clocks based on the entropy of methylation states predict chronological…
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering…
Researchers at the University of Cologne have found that mRNA-based COVID-19 vaccines have a lasting…
Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope…
Researchers report that the type of tissue samples used is crucial when assessing a person’s…
Van Andel Institute researchers discovered that cancer risk may be determined before birth due to…
A study reveals DNA and RNA epigenetics work together as a complementary system for precise…
Obesity creates lasting epigenetic changes in fat cells, making weight regain easier. Early prevention is…
Cancer is now the top cause of death in the US, with key epigenetic traits…
The study shows that frequent use of high-potency cannabis alters DNA, affecting genes related to…
A new epigenetic clock that uses easily collected cheek cells can accurately predict mortality. We…
In the embryonic development of vertebrates, 5-formylcytosine activates genes. Professor Christof Niehrs and his team…
Building on their groundbreaking research in epigenetics and transposable elements related to aging, scientists at…
DNA methylation, essential for regulating gene expression and cell function, is crucially maintained by CDCA7,…
A new study shows how a father’s diet before conception can affect his children’s health,…
In a study of cells from nearly 400 ALS patients, MIT researchers identified genomic regions…