Penn Medicine Develops Potent mRNA Vaccine Against Lethal H5N1 Virus
Experimental mRNA vaccine proves highly effective against H5N1 in animal studies, offering hope for rapid pandemic response. Researchers from the Perelman School of Medicine at…
MRNA News
Messenger RNA (mRNA) is a type of RNA molecule that plays a critical role in the process of gene expression within cells. It acts as a messenger between DNA and the protein synthesis machinery of the cell. DNA sequences are transcribed into mRNA molecules, which then carry the genetic information needed to produce proteins from the nucleus to the ribosomes, where translation occurs. Each mRNA molecule corresponds to a specific protein, encoded by a gene in the DNA. The sequence of nucleotides in the mRNA determines the sequence of amino acids in the protein, which in turn determines the protein’s structure and function. Recent advances have leveraged mRNA technology in developing vaccines, such as those for COVID-19, showcasing its potential in modern medicine and biotechnology.
Revolutionary mRNA Cancer Vaccine Shows Immense Promise in First-Ever Human Clinical Trial
In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine created at the University of Florida rapidly reprogrammed the immune system…
How mRNA Is Rewriting the Rules of Cancer Treatment
MIT spinout Strand Therapeutics has developed a new class of mRNA molecules that can sense where they are in the body, for more targeted and…
Weight Loss Launchpad: Space Tech Boosts Obesity mRNA Treatment Efficacy
Drawing inspiration from space shuttle technology, researchers at Penn Engineering have developed a novel method for synthesizing a crucial element of lipid nanoparticles (LNPs). These…
Unlocking Bacterial Secrets: The Revolutionary Tool Decoding Gene Behavior
Researchers discovered a method to expedite the study of bacterial gene regulation, which could help fight antibiotic resistance by analyzing DNA replication’s impact on gene…
Rewriting the Code: Enhancing Safety in Future mRNA Treatments
Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. They have identified…
The Future of Vaccines? Japan’s Breakthrough in 100% Pure mRNA Production
A Japanese research team has introduced the ‘Purecap’ method, enabling the production of highly pure mRNA vaccines. A research group from Japan has developed a…
Promising New Treatment for Alzheimer’s Disease: Modifying Key Messenger RNA
Complex path promotes immune cell migration and clearance of toxic protein. Reducing the methylation of a key messenger RNA can promote migration of macrophages into…
mRNA Vaccines Offer One-Two Punch To Combat Malaria – Could Help Save Millions of Lives
Research shows new mRNA vaccine technology could help researchers save millions of lives, prevent illness, and make progress toward the elimination of this ancient disease….
New Breast Cancer Treatments Inspired by mRNA COVID-19 Vaccine Innovation
Scientists at Queen’s University Belfast have received funding from Breast Cancer Now to support their quest for new treatments inspired by COVID-19 vaccine innovation. The…
New Technology Repairs and Regenerates Heart Cells After a Heart Attack
A “powerful clinical strategy” for treating heart disease may result from the recent discovery. University of Houston researchers have developed a groundbreaking technique that, in…
COVID Vaccine-Related Swelling Lasts Longer Than Initially Reported
The duration of axillary lymphadenopathy detected by breast ultrasound after COVID-19 mRNA vaccination is longer than previously reported in initial vaccine clinical trials. A new…
MIT Expert on the Progress of mRNA Vaccines
Following the successful development of COVID-19 vaccines, researchers hope to deploy mRNA-based therapies to combat many other diseases. Two mRNA vaccines, which were granted emergency…
COVID-19 mRNA Vaccine Technique Shows Promise for Treating Heart Disease
A technique for delivering genetic material to the body is being investigated as a means of repairing damaged heart muscle after a heart attack. The…
How mRNA and DNA Vaccines Could Soon Treat Cancer, HIV, Genetic Diseases, and More
The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using…
Grow and Eat Your Own Vaccines? Using Plants As mRNA Factories
Scientists are working on transforming edible plants into mRNA vaccine producers, potentially enabling vaccines to be grown in home gardens and stored without refrigeration. The…
Nanoengineers Use Flu Virus Shells To Improve Delivery of mRNA Into Cells
Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells. Their…
mRNA Vaccines Highly Effective at Preventing Death From COVID-19 – But Less Effective at Preventing Infection
A target trial emulation study found that in an elderly population of U.S. veterans with high comorbidity burden, mRNA vaccine efficacy at preventing infection with…