RNA Molecules Control Repair of Damaged Human DNA in Cancer Cells
A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that…
A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that…
A gene-silencing tool could enable new opportunities for advancing basic biomedical research and drug development. The technique draws on the power of small noncoding RNA…
Making RNA Vaccines Easier To Swallow A pill that releases RNA in the stomach could offer a new way to administer vaccines, or to deliver…
A former UBC post-doctoral research fellow led an international research team in re-analyzing all public RNA sequencing data to uncover almost ten times more RNA…
In a new study, researchers at Karolinska Institutet have identified the presence of a specific connection between a protein and an lncRNA molecule in liver…
Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body’s early antiviral defense system can protect mice from a…
DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain. Together with Jülich Research Centre (FZJ) and…
A research team at Aarhus University has developed a new molecule that attaches to the surface of SARS-CoV-2 virus particles. This attachment prevents the virus…
Biochemist studies when enzymes in our cells go wrong and misbehave in human disease. University of Delaware researcher awarded NIH grant to study why eraser…
A new study finds the clusters form small, stable droplets and may give the genome a gel-like structure. A cell stores all of its genetic…
Researchers are working on new ways to cure COVID-19 infections, using molecules that bind to three-dimensional folds in the virus’s genetic material. Credit: Martina Zafferani,…
The human genome can be thought of as a massive library, containing over 20,000 different “instruction manuals”: your genes. For example, there are genes which…
eToeholds are engineered control elements that could make RNA therapeutics safer, cell therapies more effective, and enable novel forms of biodetection. RNAs are best known…
RNA molecule suppresses prostate tumor growth. Many patients with prostate cancer are treated with drugs that lower or block hormones that fuel tumor growth. While…
A new RNA-based control switch could be used to trigger production of therapeutic proteins to treat cancer or other diseases. Researchers at MIT and Harvard…
Look deep inside the brain of someone with Alzheimer’s disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and…
New Programmable Gene Editing Proteins Found Outside of CRISPR Systems Researchers find RNA-guided enzymes are more diverse and widespread than previously believed. Within the last…
Combining lab data with supercomputing power reveals role of RNA and chromosome structure in regulating gene expression. Using supercomputer-driven dynamic modeling based on experimental data,…