“Off the Shelf” Engineered Stem Cells Created To Treat Aggressive Brain Cancer
Investigators uncovered a diagnostic method to identify receptors on cancer cells in the blood, then engineered a cell-based therapy to target and kill tumor cells…
Stem Cells
Sonic Hedgehog to the Rescue: Impressive Regeneration To Repair Large Bone Injuries
A stem cell study presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in…
New Hope for Treatment of Parkinson’s Disease: Designer Neurons
Neurodegenerative diseases cause neuronal damage and destruction, wreaking havoc on both mental and physical health. Parkinson’s disease, which affects over 10 million people worldwide, is…
Frozen Testicular Tissue Can Be Reimplanted After 20 Years and Go On To Make Viable Sperm
Research in mice holds implications for childhood cancer survivors. Male testis tissue that is cryopreserved can be reimplanted after more than two decades and will…
Plug-and-Play Human Organ-on-a-Chip Can Be Customized to the Patient
Major advance from Columbia Engineering team demonstrates the first multi-organ chip made of engineered human tissues linked by vascular flow for improved modeling of systemic…
Gene Therapy Reverses Effects of Autism-Linked Mutation in Human Brain Organoids
University of California San Diego (UCSD) study uses lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and test gene therapy tools. In…
Sleep Deprivation Impairs Stem Cells in the Cornea – Possibly Leading to Vision Impairment
Sleep deprivation, which means getting too little high-quality sleep, is a serious health problem. More than one-third of Americans report sleeping less than the suggested…
Biochemists Identify How Genome Organization Influences Cell Fate
University of California Riverside-led study identifies how blood stem cells maintain their fate. Understanding the molecular mechanisms that specify and maintain the identities of the…
Unraveling Stem Cells’ Secrets: Immortality of Germline Cells and the Function of “Junk DNA”
The MIT biologist Yukiko Yamashita’s research has shed light on the immortality of germline cells and the function of “junk DNA.” When cells divide, they…
Scientists Create First Comprehensive Map of Human Blood Stem Cell Development
UCLA scientists and colleagues have created a first-of-its-kind roadmap that traces each step in the development of blood stem cells in the human embryo, providing…
“Time Jump” by 30 Years: Old Skins Cells Reprogrammed To Regain Youthful Function
Findings could lead to targeted approach for treating aging. Research from the Babraham Institute has developed a method to ‘time jump’ human skin cells by…
Newborn Cells in the Epileptic Brain Provide a Potential Target for Anti-Seizure Medications
Over the years, everyone loses a few brain cells. A study led by scientists from USC Stem Cell and the USC Neurorestoration Center presents evidence…
Epigenetics Research Uncovers Secrets That Allow Researchers To Revamp Stem Cell Reprogramming
Researchers have identified factors required to generate naïve stem cells by reprogramming. Researchers from the Babraham Institute’s Epigenetics research program have been able to learn…
Sonic Advance: How High-Frequency Sound Waves Could Help Regrow Bones
Researchers have used sound waves to turn stem cells into bone cells, in a tissue engineering advance that could one day help patients regrow bone…
DNA Replication Speed Limit Could Be a Breakthrough for Stem Cell Therapy
Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle…
Experiments Show How Sugar Molecules Can Be Used To Track Stem Cells in the Brain
A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues…
Complex Three-Dimensional Kidney Tissue Created in the Lab From Scratch
A research team based in Kumamoto University (Japan) has created complex 3D kidney tissue in the lab solely from cultured mouse embryonic stem (ES) cells….
Cranial Neural Crest Cells: A Crowning Achievement in Understanding Head Development
Cranial neural crest cells, or CNCCs, contribute to many more body parts than their humble name suggests. These remarkable stem cells not only form most…
