Fast-Spreading Mutation Helps Common Flu Subtype Evade Immune Response and Vaccines
Finding highlights the need for flu vaccines to target multiple sites on virus. Strains of a common subtype of influenza virus, H3N2, have almost universally…
Vaccine
Flu Mutation Study: Universal Flu Vaccine May Be More Challenging Than Expected
Many flu strains may be capable of mutating to escape universal-vaccine antibodies. Some common strains of influenza have the potential to mutate to evade broad-acting…
“DNA Origami” Used by MIT Engineers to Identify Vaccine Design Rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells. By folding DNA into a virus-like…
Evidence That a Common Childhood Vaccine Helps Prevent Severe Complications of COVID-19
A paper published by Paul Fidel, Jr., PhD, Professor and Director of the Center of Excellence in Oral and Craniofacial Biology and Associate Dean for…
MMR Vaccine Could Protect Against the Worst COVID-19 Symptoms – “A Low-Risk-High-Reward Preventive Measure”
Administering the MMR (measles, mumps, rubella) vaccine could serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection, say a team of…
Newly Developed Vaccines Protect Against COVID-19 in Macaques Study
Companion study suggests COVID-19 infection protects against re-exposure. With nearly 5 million confirmed cases globally and more than 300,000 deaths from COVID-19, much remains unknown…
Vaccines Find More Success in Development Than Any Other Kind of Drug, but …
How often do vaccine trials hit paydirt? Study: Vaccines find more success in development than any other kind of drug, but have been relatively neglected…
Building Artificial Proteins Like LEGOs to Design New Vaccines
Vaccines are one of the most effective interventions to prevent the spreading of infectious diseases. They trigger the immune system to produce antibodies that protect…
Single Dose of ChAdOx1 nCoV-19 Vaccine Protects Monkeys Against COVID-19 Pneumonia
Study provided data for clinical testing to commence. A single dose of ChAdOx1 nCoV-19, an investigational vaccine against SARS-CoV-2, has protected six rhesus macaques from…
Genetic Mutations in SARS-CoV-2 Coronavirus Provide Insights Into Virus Evolution
By analyzing virus genomes from over 7,500 people infected with Covid-19, a UCL-led research team has characterized patterns of diversity of SARS-CoV-2 virus genome, offering…
A Polio Vaccine That Hasn’t Been Used in the U.S. for Two Decades Might Protect Against Coronavirus [Video]
The COVID-19 pandemic has scientists considering a few less-conventional options while vaccines against SARS-CoV-2 are being developed. One option might be the oral polio vaccine….
Russia Creates Custom “Humanized” Mice to Test COVID-19 Drugs and Vaccines
Following the recent Coronavirus outbreak, almost three million people have been infected worldwide, whereas the death toll has already passed the 200,000 mark, according to…
Varying Virus-Specific Antibodies in Recently Recovered COVID-19 Patients
Most newly discharged patients who recently recovered from COVID-19 produce virus-specific antibodies and T cells, suggests a study published on May 3rd in the journal…
Bat ‘Super Immunity’ May Explain How Bats Carry Coronaviruses Without Getting Sick
Bat-virus adaptation may explain species spillover, researchers say. A University of Saskatchewan (USask) research team has uncovered how bats can carry the Middle East respiratory…
Infection Researchers Identify How Coronaviruses From Animals Need to Change to Spread to Humans
Infection researchers from the German Primate Center identify starting points for vaccine development and therapy. The SARS coronavirus 2 (SARS-CoV-2) infects lung cells and is…
Progress on AAVCOVID, A Gene-Based Experimental COVID-19 Vaccine
AAVCOVID technology is unique in the vaccine field in its ability to scale and adapt rapidly. Massachusetts Eye and Ear and Massachusetts General Hospital (MGH),…
Antibody Discovered That Blocks Infection by SARS-CoV-2 (COVID-19 Coronavirus) in Cells
Initial step towards developing fully human antibody therapeutics and diagnostics for COVID-19. Researchers at Utrecht University, Erasmus Medical Center and Harbour BioMed (HBM) today reported…
New Clues on How to Treat COVID-19 From T Cell Counts and Cytokine Storms
Inflammatory immune response can cause T cells to become depleted, affecting patient outcomes in coronavirus cases and leaving them prone to secondary infection. Cytokine storms…