Stem Cells News

New Technique Uses Regenerative Capacity of Stem Cells to Eliminate HIV

July 6, 2015

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Stem Cell Gene Therapy Holds Promise for Eliminating HIV

Scientists at UCLA have developed a new technique that harnesses the regenerative capacity of stem cells to generate an immune response to HIV, showing that the technique decreased HIV levels in mice by 80 to 95 percent. Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are one […]

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Protein NELL-1 Stimulates Significant Bone Growth

July 1, 2015

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Study Reveals Bone-Building Protein’s Impact on Bone Stem Cells

In a newly published study, scientists from UCLA reveal that the protein NELL-1 stimulates significant bone formation through the regenerative ability of stem cells. These preclinical results could one day have an impact on the development of a treatment for osteoporosis, which affects more than 200 million people worldwide, as well as potentially help those […]

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CCNE1 Gene Turns Back Cellular Clock

May 22, 2015

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Researchers Discover Human-Specific Gene That Turns Back Cellular Clock

Yale researchers have discovered a gene that turns back the cellular clock, greatly aiding the reprogramming of mature cells. An exhaustive analysis of factors that allow mature cells to become like embryonic stem cells again has revealed a spliced form of a gene found only in primates that greatly aids the reprogramming of mature cells. […]

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Targeting Brain Metastases with Stem Cell Therapy

April 27, 2015

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Targeting Breast to Brain Metastatic Tumor

Researchers have developed an in vivo imageable breast-to-brain metastasis mouse model. Using real time in vivo imaging and subsequent composite fluorescence imaging, they show a widespread distribution of micro- and macro-metastasis in different stages of metastatic progression. Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital (MGH) have developed an “imageable” mouse model of […]

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Researchers Identify a Vital Protein for Brain Development

March 16, 2015

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Researchers Identify a Vital Protein

Researchers from the Harvard Stem Cell Institute have identified a vital protein that can help determine embryonic development. A protein that is necessary for the formation of the vertebrate brain has been identified by researchers at the Harvard Stem Cell Institute (HSCI) and Boston Children’s Hospital, in collaboration with scientists from Oxford and Rio de […]

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Possible Signs of Progress in the Fight Against Parkinson’s

March 4, 2015

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Signs of Progress Against Parkinson’s

By using induced pluripotent stem cells, researchers have markedly reduced the symptoms Parkinson’s disease in primates. Harvard Stem Cell Institute (HSCI) researchers at University-affiliated McLean Hospital have taken what they describe as an important step toward using the implantation of stem cell-generated neurons as a treatment for Parkinson’s disease. Ole Isacson and colleagues reported that […]

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A Pill to Shed Fat? Researchers Turn White Fat Cells Into Brown Fat Cells

December 10, 2014

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Researchers Turn White Fat Cells into Brown Fat Cells

Scientists from Harvard have created a system using human stem cells to screen for compounds that have the potential to turn white fat cells into brown fat cells. Harvard Stem Cell Institute (HSCI) researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of […]

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Research Reveals New Strategy to Control Cellular Identity and Fate

December 5, 2014

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A New Strategy to Control Cellular Identity and Fate

Newly published research suggests a new strategy to control cellular identity and fate, revealing that depleting or knocking out a chemical tag on RNA keeps embryonic stem cells in suspended animation. A team of scientists that included researchers from UCLA has discovered a novel mechanism of RNA regulation in embryonic stem cells. The findings are […]

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New Gene-Editing Technique Could Prove to be an Effective Technique for Blocking HIV

November 11, 2014

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Researchers Genetically Edit Human Blood Stem Cells

Using CRISPR Cas technology, researchers genetically ‘edit’ human blood stem cells to create what could prove to be an effective technique for blocking HIV. Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General (MGH) and Boston Children’s hospitals (BCH) for the first time have used a relatively new gene-editing technique to create what could prove […]

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UCLA Scientists Propose a Benchmark for Better Stem Cell Replication

November 10, 2014

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Scientists Propose Benchmark for Better Replication of Natural Stem Cells

New research from UCLA establishes a standard to assess how conditions used to procure stem cells in the lab compare to those found in a human embryo, and could provide the foundation for scientists to more precisely replicate natural stem cell development in an artificial environment. The study, which was led by Guoping Fan, professor […]

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Scientists Discover Protein That Can Accelerate Recovery

October 22, 2014

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Scientists Discover Protein That Can Accelerate Cancer Recovery

New research from UCLA’s Jonsson Comprehensive Cancer Center reveals how a unique protein found in human bone marrow can drive stem cells to repair our blood system after an injury, providing a roadmap that could help scientists make existing radiation and chemotherapy treatments more effective for people with cancer and other blood-related diseases. Led by […]

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Researchers Reset Human Pluripotent Stem Cells to a Fully Pristine State

September 12, 2014

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Researchers Reset Human Pluripotent Stem Cells to a Fully Pristine State

A newly published study details how scientists were able to successfully ‘reset’ human pluripotent stem cells to a fully pristine state. Researchers at EMBL-EBI have resolved a long-standing challenge in stem cell biology by successfully ‘resetting’ human pluripotent stem cells to a fully pristine state, at the point of their greatest developmental potential. The study, […]

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New Stem Cell Research Identifies Barriers to Human iPSC Generation

July 31, 2014

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New Stem Cell Research May Make Tissue Regeneration More Efficient

UC San Francisco scientists detail new research that might lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts. The finding are published in the current edition of Cell. The work builds on a strategy that involves reprogramming adult […]

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New Way to Regrow Human Corneas Could Help Overcome a Major Cause of Blindness

July 16, 2014

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A New Way to Regrow Human Corneas

Harvard-affiliated researchers have discovered a new way to regrow human corneas that could help researchers overcome a major cause of blindness. Researchers have identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule that acts as a marker for hard-to-find limbal stem cells. This work, a collaboration among the […]

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Scientists Coax Human Embryonic Stem Cells to Organize

July 1, 2014

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Researchers Coax Human Embryonic Stem Cells to Organize

Using geometry, scientists from the Laboratory of Stem Cell Biology and Molecular Embryology at Rockefeller University have coaxed human embryonic stem cells to organize themselves. About seven days after conception, something remarkable occurs in the clump of cells that will eventually become a new human being. They start to specialize. They take on characteristics that […]

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Researchers Use Stem Cells from Teeth to Grow Brain-Like Cells

May 1, 2014

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Researchers Make Brain Like Cells from Teeth Stem Cells

New research from the University of Adelaide shows that stem cells from teeth can develop and form complex networks of brain-like cells. University of Adelaide researchers have discovered that stem cells taken from teeth can grow to resemble brain cells, suggesting they could one day be used in the brain as a therapy for stroke. […]

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Researchers Identify Major Obstacle to Converting Cells Back to Their Youthful State

January 31, 2014

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Researchers Identify Major Obstacle to Converting Cells Back to Their Youthful State

Researchers from Yale University have identified a major obstacle to converting cells back to their youthful state — the speed of the cell cycle, or the time required for a cell to divide. A fundamental axiom of biology used to be that cell fate is a one-way street — once a cell commits to becoming […]

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Researchers Convert Human Stem Cells to Functional Lung Cells

December 3, 2013

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Researchers Convert Human Stem Cells to Functional Lung Cells for the First Time

In a newly published study, researchers from the Columbia University Medical Center detail how they successfully converted human stem cells into functional lung and airway cells for the first time. New York, New York — For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells. The advance, […]

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