Tag Archives: stem cells

Embryonic Stem Cells Will Kill Themselves to Protect the Embryo

May 7, 2012

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active Bax (red) located at Golgi of human embryonic stem cells

While researching embryonic stem cells, scientists at the UNC School of Medicine discovered that by housing a protein called Bax in its active form in the Golgi, embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. Chapel Hill, North Carolina – Embryonic stem [...]

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Engineered Stem Cells Suppress HIV in Living Tissues

April 16, 2012

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HIV virus

A new study shows that genetically engineered stem cells can be used as HIV-fighting cells. Researchers at UCLA were able to expand on previous research and demonstrated for the first time stem cells engineered to form immune cells that target HIV are effective in suppressing the virus in living tissues. Expanding on previous research providing [...]

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Locomotion Restored in Mice with Huntington’s-Like Condition

March 15, 2012

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stem cells could help restore the muscle coordination deficits

A new study showed that locomotion could be restored in mice with a Huntington’s-like condition by using GABA neurons forged from human embryonic stem cells. The study shows that the cells integrated into the brain, projected to the right target and effectively reestablished the broken communication network, restoring motor function. MADISON – Huntington’s disease, the [...]

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Preventing Blood Stem Cell Differentiation by Nutrition and Insulin

March 13, 2012

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insulin and nutrition prevent blood stem cells from differentiating into mature blood cells in Drosophila

While studying the common fruit fly, UCLA stem cell researchers found that blood stem cells are receiving systemic signals from insulin and nutritional factors, which helped them from differentiating into blood cells. UCLA stem cell researchers have shown that insulin and nutrition prevent blood stem cells from differentiating into mature blood cells in Drosophila, the [...]

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Transplants Without the Need for Lifelong Immunosupression

March 8, 2012

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mystery-facilitating-cells

As a result of organ transplantation, patients need to take a lifelong regimen of immunosuppressors to fight off graft-versus-host disease (GvHD), which is common and often deadly. Now, researchers have been able to completely replace people’s bone-marrow-derived stem cells with those from unrelated donors without causing GvHD. This means that the recipients could also accept [...]

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Stem Cells Discovered in Ovaries May Yield More Eggs

February 28, 2012

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human-egg-fertilized

A new study suggests that the stem cells located in human ovaries might be able to produce new eggs. The findings were published in the journal Nature Medicine and could potentially mean an end to IVF procedures. The researchers derived a rigorous way to isolate these cells for the first time, and suggest that they [...]

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Cholera Kills off its Microbial Rivals by Jabbing Them with a Spring-Loaded Poison Dagger

February 27, 2012

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Researchers at Harvard Medical School and the California Institute of Technology teamed up to image the T6SS system working in real-time to prove their hypothesis that cholera’s T6SS tactic mirrors the system that phage viruses use to inject their genetic material into bacteria for replication. Bacteria live in a state of perpetual warfare, with different [...]

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Microfluidic Device Can Isolate Target Cells Faster than Existing Devices

February 22, 2012

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Green cells adhere weakly without tethers and are rapidly removed

Researchers at MIT and Massachusetts General Hospital have demonstrated a new microfluidic device that can isolate target cells much faster than existing devices and may lead to improvements in point-of-care diagnostics and personalized medicine. Separating complex mixtures of cells, such as those found in a blood sample, can offer valuable information for diagnosing and treating [...]

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Researchers Develop Gene Therapy, Promotes Remyelination in a Mouse Model of MS

February 15, 2012

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Gene Therapy to Boost Brain Repair

Researchers at California Institute of Technology (Caltech) believe they have found a way to help the brain replace damaged oligodendrocytes and myelin. By using a system of gene therapy they developed, which uses leukemia inhibitory factor (LIF), the researchers were able to stimulate production of new oligodendrocytes from stem and progenitor cells. PASADENA, California — [...]

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Stem Cells Help Re-grow Healthy Heart Muscle After Heart Attack

February 14, 2012

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stem-cell-therapy-heart-attack

A new study published in the journal The Lancet shares the results from a Cedars-Sinai Heart institute clinical trial, which demonstrated that heart attack patients could be treated with an infusion of their own heart-derived cells that helped re-grow healthy heart muscles. The patients who underwent the stem cell procedure showed a significant reduction in [...]

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Researchers Develop New Method to Create Mesenchymal Stem Cells (MSCs)

February 13, 2012

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University of Queensland

Researchers at the University of Queensland developed a new method to create mesenchymal stem cells (MSCs), which can be used to repair bone and potentially other organs. The technique could lead to future widespread clinical use of MSCs. University of Queensland scientists have developed a world-first method for producing adult stem cells that will substantially [...]

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Researchers Use Human Neurons to Investigate Parkinson’s Disease

February 8, 2012

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Researchers Discover Genetic Origins of Parkinson’s Disease

Researchers at the University of Buffalo’s School of Medicine and Biomedical Sciences used human neurons to help solve the genetic origins of Parkinson’s disease. Based a previous method in which they used induced pluripotent stem cells, their findings show that mutations disrupt the precise action of dopamine and produce more free radicals leading to Parkinson’s. [...]

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