Research Shows That Robotic Surgery Is Safer and Improves Patient Recovery Time by 20%

Robotic Surgery

Research from the University College London and the University of Sheffield has shown that robot-assisted surgery for bladder cancer removal and repair allows patients to recover much faster and spend considerably less time in the hospital.

A new study has found that robotic surgery is less dangerous and has a faster recovery period for patients

Robotic surgery, also known as robot-assisted surgery, enables surgeons to conduct a variety of complicated operations with more precision, flexibility, and control than traditional approaches allow.

Robotic surgery is often associated with minimally invasive surgery, which involves procedures carried out through small incisions. It’s also occasionally employed in certain traditional open surgical procedures.

The most common clinical robotic surgical system consists of a camera arm and mechanical arms with surgical tools attached. While sitting at a computer station beside the operating table, the surgeon controls the arms. The console provides the surgeon with a magnified, high-definition 3D view of the operative site.

A first-of-its-kind clinical trial led by scientists at University College London and the University of Sheffield found that using robot-assisted surgery to remove and rebuild bladder cancer allows patients to recover much faster and spend considerably (20%) less time in hospital.

The study, which was published in JAMA on May 15th and funded by The Urology Foundation with a grant from the Champniss Foundation, also discovered that robotic surgery cut the chance of readmission in half (52%) and revealed a “striking” four-fold (77%) reduction in the prevalence of blood clots (deep vein thrombus & pulmonary emboli) – a significant cause of health decline and morbidity – when compared to patients who had open surgery.

Patients’ stamina and quality of life also improved and their physical activity increased which was measured by daily steps recorded on a wearable smart sensor.

Unlike open surgery, which involves a surgeon working directly on a patient and large incisions in the skin and muscle, robot-assisted surgery enables doctors to remotely guide less invasive tools using a console and 3D view. It is currently only offered at a few UK hospitals.

Researchers say the findings provide the strongest evidence so far of the patient benefit of robot-assisted surgery and are now urging the National Institute of Clinical Excellence (NICE) to make it available as a clinical option across the UK for all major abdominal surgeries including colorectal, gastrointestinal, and gynecological.

Co-Chief Investigator, Professor John Kelly, Professor of Uro-Oncology at UCL’s Division of Surgery & Interventional Science and consultant surgeon at University College London Hospitals, said: “Despite robot-assisted surgery becoming more widely available, there has been no significant clinical evaluation of its overall benefit to patients’ recovery. In this study we wanted to establish if robot-assisted surgery when compared to open surgery, reduced time spent in hospital, reduced readmissions, and led to better levels of fitness and quality of life; on all counts, this was shown.

“An unexpected finding was the striking reduction in blood clots in patients receiving robotic surgery; this indicates a safe surgery with patients benefiting from far fewer complications, early mobilization and a quicker return to normal life.”

Co-Chief Investigator Professor James Catto, Professor of Urological Surgery at the Department of Oncology and Metabolism, University of Sheffield, said: “This is an important finding. Time in hospital is reduced and recovery is faster when using this advanced surgery. Ultimately, this will reduce bed pressures on the NHS and allow patients to return home more quickly. We see fewer complications from improved mobility and less time spent in bed.

“The study also points to future trends in healthcare. Soon, we may be able to monitor recovery after discharge, to find those developing problems. It is possible that tracking walking levels would highlight those who need a district nurse visit or perhaps a check-up sooner in the hospital.”

“Previous trials of robotic surgery have focused on longer-term outcomes. They have shown similar cancer cure rates and similar levels of long-term recovery after surgery. None have looked at differences in the immediate days and weeks after surgery.”

Open surgery remains the NICE “gold standard” recommendation for highly complex surgeries, though the research team hopes this could change.

Professor Kelly added: “In light of the positive findings, the perception of open surgery as the gold standard for major surgeries is now being challenged for the first time.

“We hope that all eligible patients needing major abdominal operations can now be offered the option of having robotic surgery.”

Rebecca Porta, CEO of The Urology Foundation said: “The Urology Foundation’s mission is simple – to save lives and reduce the suffering caused by urological cancers and diseases. We do this through investing in cutting-edge research, leading education, and supporting the training of health care professionals to ensure that fewer lives will be devastated.

“We are proud to have been at the heart of the step change in the treatment and care for urology patients since our inception 27 years ago, and the outcomes of this trial will improve bladder cancer patients’ treatment and care.”

Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle and can lead to secondary cancer in other parts of the body. About 10,000 people are diagnosed with bladder cancer in the UK every year and over 3,000 bladder removals and reconstructions are performed. It is one of the most expensive cancers to manage.

Trial findings

Across nine UK hospitals, 338 patients with non-metastatic bladder cancer were randomized into two groups: 169 patients had robot-assisted radical cystectomy (bladder removal) with intracorporeal reconstruction (the process of taking a section of bowel to make a new bladder), and 169 patients had open radical cystectomy.

The trial’s primary end-point was the length of stay in the hospital post-surgery. On average, the robot-assisted group stayed eight days in the hospital, compared to 10 days for the open surgery group – so a 20% reduction. Readmittance to the hospital within 90 days of surgery was also significantly reduced – 21% for the robot-assisted group vs 32% for open.

A further 20 secondary outcomes were assessed at 90 days, six- and 12 months post-surgery. These included blood clot prevalence, wound complications, quality of life, disability, stamina, activity levels, and survival (morbidity). All secondary outcomes were improved by robot-assisted surgery or, if not improved, almost equal to open surgery.

This study, and previous studies, show both robot-assisted and open surgery are equally as effective in regard to cancer recurrence and length of survival.

Next steps

The research team is conducting a health economic analysis to establish the quality-adjusted life-year (QALY), which incorporates the impact on both the quantity and quality of life.

Patient case studies

John Hammond, retired, age 75, from Doncaster, said: “I left my symptoms too long, and found out that I had a tumor in the bladder. I was lucky to see Professor Catto and after being given options, I chose the operation to have my bladder removed and a stoma in place.

“I had the operation in August 2019 and was aware that it was robotic surgery in a trial and was keen to take part; in fact, I was pleased to be in a position to help anybody else in the future with this type of surgery. The operation was successful, and the whole team was hugely supportive.

“Amazingly, I was walking the next day and progressed excellently, improving my walking each day. I was in no pain and just had to adjust to the stoma bag. I have fully recovered from the operation and throughout I knew I was in professional hands. I was home about five days after surgery and am grateful to Professor Catto and his team that I did not have to stay in hospital for longer than necessary.”

Frances Christensen Essendon, from Hertfordshire, said: “I was diagnosed with bladder cancer and after a course of chemotherapy it was suggested that I have my bladder removed. Under Professor John Kelly I underwent robotic surgery to remove my native bladder which was replaced with a new bladder made out of the bowel. The operation was a success, and I was up and walking soon after surgery. Having had the operation in April I was back to work and the gym in the middle of June. I have gone on to lead a normal active life and am eternally grateful to Prof Kelly and his team for their care and support.”

The trial took place from March 2017 to March 2020 and involved 29 surgeons at nine UK hospital trusts namely; University College London Hospitals NHS Foundation Trust, Sheffield Teaching Hospitals NHS Foundation Trust, Guys and St Thomas’ NHS Foundation Trust, NHS Greater Glasgow and Clyde, Royal Berkshire NHS Foundation Trust, St James University Hospital Leeds, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Royal Devon and Exeter NHS Trust, and North Bristol NHS Trust.

Reference: “Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer” by James W. F. Catto, Pramit Khetrapal, Federico Ricciardi, et al., 15 May 2022, JAMA.
DOI: 10.1001/jama.2022.7393

1 Comment on "Research Shows That Robotic Surgery Is Safer and Improves Patient Recovery Time by 20%"

  1. William Readling | July 1, 2022 at 1:13 pm | Reply

    It’s not a robot. It’s a Waldo. It’s a remotely piloted surgery vehicle.

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