Study Shows Tiny DNA Modification Has Big Impact on Tumors
A simple modification of a DNA base in small areas of the genome may explain why glioblastoma tumors are so deadly, researchers at Yale and…
A simple modification of a DNA base in small areas of the genome may explain why glioblastoma tumors are so deadly, researchers at Yale and…
The International Vertebrate Genomes Project (VGP) has officially launched and released 15 new reference genomes representing all five vertebrate classes – mammals, birds, reptiles, amphibians,…
The combination of a new sequencing technique and machine learning can speed up the diagnosis of diseases in newborns and reduce false-positive results, Yale researchers…
A study by a Massachusetts General Hospital (MGH) research team finds that neurogenesis — inducing the production of new neurons — in the brain structure…
A research team at the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and Harvard Medical School (HMS) reports a new kind of…
Several gene mutations have been linked to Parkinson’s disease, but exactly how and where some of them cause their damage has been unclear. A new…
Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found that cancers are driven by a breakdown in how cells repair their…
Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in…
With the combined efforts of three Yale laboratories, researchers conducted the first demonstration of site-specific gene editing in a fetus, correcting a mutation that causes…
Scientists have identified a key enhancer of Sox9 — a gene critical for male sex development — and demonstrated that deleting that non-coding DNA results…
People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients…
During embryonic development genetic cascades control gene activity and cell differentiation. In a new publication of the journal PNAS, the team of Ulrich Technau of…
Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in…
An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program…
Researchers from Columbia University have developed a new technique for the powerful gene-editing tool CRISPR to restore retinal function in mice afflicted by a degenerative…
MIT biologists have discovered a function of a gene that is believed to account for up to 40 percent of all familial cases of amyotrophic…
Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of…
In a new study of languages spoken in 43 different populations worldwide, Yale School of Medicine researchers and their colleagues identified variants of a dyslexia…