PROTACs: A New Type of Drug That Can Target All Disease-Causing Proteins
A newly published study from Yale University details the discovery of a new type of drug, called Proteolysis Targeting Chimeras (PROTACs), which can target all…
Protein
Yale Research Shows How Renalase Protects Kidney and Heart from Injury
A newly published study from Yale University details how the protein renalase protects cells from the type of severe injury that could result in a…
Scientists Discover Protein That Can Accelerate Recovery
New research from UCLA’s Jonsson Comprehensive Cancer Center reveals how a unique protein found in human bone marrow can drive stem cells to repair our…
Theorists Show How Energy Landscapes Dominate Both Evolution and Folding of Proteins
A team of biophysicists at Rice University used computer models to show that the energy landscape involved in the long-term evolution of proteins is essentially…
Scientists Report a Big Leap in Understanding How PP1 Interacts with Other Proteins
In a newly published study, researchers at Brown University report a big leap in understanding how PP1 interacts with other proteins to behave specifically in…
Yale Researchers Create a 21st Amino Acid
Using bacteria, Yale researchers rewrite most of the genetic instructions that encode all 20 amino acids, creating a specific 21st amino acid. Yale researchers have…
Better Protein Creation is the Key to Longevity for the Naked Mole Rat
In a newly published study, University of Rochester researchers show that better constructed proteins are the key to the naked mole rat’s longevity and health….
Yale Scientists Discover Alzheimer’s Missing Link
In a newly published study, Yale researchers reveal that a protein within the cell membrane called metabotropic glutamate receptor 5 is the missing link in…
Researchers Solve Biological Mystery about the Common Genesis of Many Serious Diseases
Scientists solve a biological mystery about the common genesis of many serious diseases, discovering a trigger to important biologic responses such as the control of…
Newly Discovered Small Molecule Inhibitor Boosts Insulin Signaling
Harvard Medical School researchers have uncovered a new pathway in insulin resistance and show that a newly discovered small-molecule inhibitor can interrupt this pathway and…
New Analysis on Iceman Ötzi Opens Up New Research Possibilities for Mummies
Using a pinhead-sized sample of brain tissue from the Iceman Ötzi, scientists were able to identify numerous brain proteins, as well as proteins from blood…
Protein Makes Old Hearts Younger, Reverses Some Effects of Aging
Researchers have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for a form of…
A Closer Look at the Antifreeze Protein that Allows Siberian Beetles to Survive
A newly published study from Yale University looks at longhorn beetle Rhagium inquisitor and its ability to supercool to below -25°C, examining the unusual structure…
New Data Offers Clues on the Origins of Life
A new study offers clues on the origins of life, providing data to support the idea that the 10 amino acids believed to exist on…
Stressed VWF Proteins Can Cause Blood Clots
Focusing on a protein called von Willebrand factor (VWF), a team of scientists discovered how stresses of blood flow in small blood vessels of the…
Nano-Machines Recreate Principal Activities of Proteins
Using a high performance computing infrastructure, a team of researchers developed the first versatile and modular example of a fully artificial protein-mimetic model system that…
Artificial Enzyme Reveals Never Before Seen Structure
A newly published study details how researchers turned an ordinary protein into an artificial enzyme, a biological catalyst capable of joining two segments of RNA….
Enzyme’s Essential Role in Long-Term Memory Refuted
The enzyme protein kinase M-ζ (PKM-ζ) was thought to be a fixture of long-term memory, as its inhibition could erase old memories, whilst adding it…