Yale Scientists Discover Alzheimer’s Missing Link
In a newly published study, Yale researchers reveal that a protein within the cell membrane called metabotropic glutamate receptor 5 is the missing link in…
Protein
Researchers Solve Biological Mystery about the Common Genesis of Many Serious Diseases
Scientists solve a biological mystery about the common genesis of many serious diseases, discovering a trigger to important biologic responses such as the control of…
Newly Discovered Small Molecule Inhibitor Boosts Insulin Signaling
Harvard Medical School researchers have uncovered a new pathway in insulin resistance and show that a newly discovered small-molecule inhibitor can interrupt this pathway and…
New Analysis on Iceman Ötzi Opens Up New Research Possibilities for Mummies
Using a pinhead-sized sample of brain tissue from the Iceman Ötzi, scientists were able to identify numerous brain proteins, as well as proteins from blood…
Protein Makes Old Hearts Younger, Reverses Some Effects of Aging
Researchers have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for a form of…
A Closer Look at the Antifreeze Protein that Allows Siberian Beetles to Survive
A newly published study from Yale University looks at longhorn beetle Rhagium inquisitor and its ability to supercool to below -25°C, examining the unusual structure…
Stressed VWF Proteins Can Cause Blood Clots
Focusing on a protein called von Willebrand factor (VWF), a team of scientists discovered how stresses of blood flow in small blood vessels of the…
Nano-Machines Recreate Principal Activities of Proteins
Using a high performance computing infrastructure, a team of researchers developed the first versatile and modular example of a fully artificial protein-mimetic model system that…
Artificial Enzyme Reveals Never Before Seen Structure
A newly published study details how researchers turned an ordinary protein into an artificial enzyme, a biological catalyst capable of joining two segments of RNA….
Enzyme’s Essential Role in Long-Term Memory Refuted
The enzyme protein kinase M-ζ (PKM-ζ) was thought to be a fixture of long-term memory, as its inhibition could erase old memories, whilst adding it…
Link Between Cell Death & Protein Clumps Could Lead to Possible Treatment for Parkinson’s
A rogue protein involved in Parkinson’s disease that wrecks catastrophic damage has been tracked down by researchers in work that could help find a new…
Proteins Engineered With Predictable Structures
Proteins fold spontaneously into precise conformation, time after time, optimized by evolution. Yet given the number of contortions possible for chains of amino acids, dictating…
SSRL Validates Anti-Flu Protein Design
A team of scientists designed proteins from scratch to have a high affinity and high specificity for targets on flu viruses, validating the two best…
Study Reveals How Lis1 Regulates Dynein Motility
By using common baker’s yeast as a model system, Harvard researchers discovered how the key motor protein dynein interacts with a molecule called Lis1. Molecular…
SIRT1 Protein Slows Aging and Protects Against Diabetes
A new study from MIT looks at what happens when the SIRT1 protein is missing from adipose tissue in mice, finding that SIRT1 protects from…
New Design Makes Previously Inaccessible Proteins Vulnerable to Drugs
A team of researchers at Yale University have identified a molecular signal that allows potentially therapeutic proteins to hitch a ride into cells using vesicles,…
Chitinase 3-like-1, A Key to Fighting Pneumonia
While working with mice, scientists at Yale University found that the protein Chitinase 3-like-1 (Chi3l1) was crucial in regulating the immune response to Streptococcus pneumonia,…
Genes Down-Regulated in Spaceflight Extend the Lifespan of Worms
A team of scientists discovered that spaceflight suppressed the accumulation of toxic proteins and a group of genes, which when lowered in worms back on…