Proteins in a Cancerous Tumor’s Microenvironment Have Role in Drug Resistance
Two different studies published in the journal Nature reveal that cancers can resist destruction by drugs with the help of proteins recruited from surrounding tissues….
Protein
A New and Possibly More Effective Method for Editing Genomes
A team of scientists at the Berkeley Lab has discovered the mechanism behind the RNA-guided cleavage of double-stranded DNA that is central to the bacterial…
The Mechanics of Cellular Wound Healing
A newly published study describes how a cell reorganizes its infrastructure to heal a wound, finding that for this process the cell uses formins, key…
p65 Protein and its Interaction with Telomerase RNA
Using both X-ray crystallography and nuclear magnetic resonance spectroscopy, UCLA biochemists have examined the structure of p65 protein and its interaction with telomerase RNA. UCLA…
Evolution Helps Deduce the Shape of 18 Families of Transmembrane Proteins
Scientists at Harvard Medical School developed algorithms that allowed them to use evolution as their guide to deduce the three-dimensional structure of 18 families of…
Nanoscale Molecular Cages May Aid in Drug and Vaccine Delivery
Biochemists at UCLA used computer models to identify proteins that could be combined to form tiny molecular cages that are hundreds of times smaller than…
New Antibody Drug Boosts the Immune System’s Capacity to Fight Cancer
A new study using antibody drug BMS-936558 (MDX-1106, anti-PD-1), resulted tumor shrinkage of at least 30 percent in 18 percent of the lung cancer patients,…
LCLS Analyzes Tiny Protein Crystals
By using the Linac Coherent Light Source at Stanford to analyzed tiny protein crystals, scientists demonstrated the potential of free-electron lasers for obtaining the structures…
Researchers Identify BAD as Key Seizure-Suppressing Protein
New research from the Harvard Medical School and the Dana-Farber Cancer Institute examines why a diet high in fat and low in carbohydrates can reduce…
Crowding Causes Internal Cell Structure Alignment
By mimicking the crowded environment in actual cells, a team of researchers found that certain molecules organize as they would in the body, inducing a…
Spider Fangs May Lead to the Development of New Specialized Materials
Looking to nature for technological inspiration is nothing new and now a team of scientists are hoping that new insights into spider fangs and the…
Cdt1 Protein Has a Role in DNA Replication and Mitosis
Newly published research from biochemists at the University of North Carolina School of Medicine describes how a protein that is required for DNA replication, Cdt1,…
Flavonoid Compound Shown to Prevent Blood Clots
Newly published findings from the Beth Israel Deaconess Medical Center describe how rutin was shown to inhibit the formation of blood clots in an animal…
HDL Cholesterol Isn’t Always Good for Your Heart
Contrary to popular belief, HDL cholesterol isn’t always good for your heart. A new study published by Harvard researchers describes how some high-density lipoprotein (HDL)…
Entropy and Particle Shape Cause Chirality in Dense Systems
To better understand why functional molecules in our bodies almost always occur in just one chiral form, UCLA scientists sought to discover how chirality occurs….
Radio-Wave Heated Nanoparticles Trigger Insulin Production in Mice
Researchers have been able to remotely activate genes inside mice, proving the concept that one day, there will be medical procedures in which patients’ genes…
Secreted Peptide Dilp8 Essential to Insect Growth Rate
Two published studies from independent research groups show that Dilp8 is an essential part of normal insect development, slowing growth rate and allowing sufficient time…
New Insight on Mitotic Spindle Architecture
New research from scientists at Harvard University examines the mitotic spindle, finding that the spindle is more complex than previously thought. Using a femtosecond laser…