Yale University News

How the Immune System Combats Superinfection

August 29, 2014

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How the Immune System Combats Superinfection

New research from Yale University shows how the immune system combats superinfections, revealing a biological basis for new vaccines against sexually transmitted diseases and possibly HIV. The immune system is great at making sure infections such as the herpes virus do not repeatedly infect a person, a condition known as a superinfection. Yet how the […]

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Research Reveals Evolution Used Similar “Toolkits” to Shape Flies, Worms, and Humans

August 29, 2014

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Evolution of Flies, Worms and Humans Share Patterns of Gene Expression

Several newly published studies reveal that flies, worms and humans share ancient patterns of gene expression. Although separated by hundreds of millions of years of evolution, flies, worms, and humans share ancient patterns of gene expression, according to a massive Yale-led analysis of genomic data. Two related studies led by scientists at Harvard and Stanford, […]

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Yale and Columbia Biologists Shed New Light on Cell Division

August 22, 2014

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Researchers Shed New Light on the Rings That Make Cell Division Possible

A team of scientists from Yale and Columbia universities has shed new light on the mechanics of the division of cells that makes life possible. Forming like a blown smoke ring does, a “contractile ring” similar to a tiny muscle pinches yeast cells in two. The division of cells makes life possible, but the actual […]

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Magneto-Optical Trapping of Strontium Monofluoride

August 21, 2014

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Physicists Chilled Molecules to Very Near to Absolute Zero

Using magneto-optical trapping, Yale physicists cooled molecules of strontium monofluoride to 2.5 thousandths of a degree above absolute zero, the lowest temperature yet achieved by direct cooling of a molecule. It’s official. Yale physicists have chilled the world’s coolest molecules. The tiny titans in question are bits of strontium monofluoride, dropped to 2.5 thousandths of […]

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Heart Disease and Strokes Decrease Significantly

August 20, 2014

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Heart Disease and Strokes Decrease in the USA

Using data from the past decade, a new study shows that the rates of U.S. hospitalizations and deaths from heart disease and stroke have dropped significantly. In some positive news for heart disease and stroke patients, Yale School of Medicine researchers report that the rates of U.S. hospitalizations and deaths from both conditions dropped significantly […]

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Neurologists Discover New Method to Fight Glioblastomas

August 14, 2014

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Researchers Discover Weakness in Glioblastoma Defenses

By targeting a protein crucial in the early development of the brain, researchers discovered that they can block multiple signaling pathways implicated in glioblastoma growth and have reduced human tumors in mouse models of the disease. Glioblastoma is a complex, deadly, and hard-to-treat brain cancer, but Yale School of Medicine researchers may have found the […]

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Nanomaterials Give Immune Cells a Cancer-Fighting Boost

August 14, 2014

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Naomaterials Give New Cancer Immunotherapy a Boost

Using bundled carbon nanotubes to incubate cytotoxic T cells, Yale scientists have developed a new cancer immunotherapy that enhances a patient’s immune response to fight cancer. Scientists at Yale University have developed a novel cancer immunotherapy that rapidly grows and enhances a patient’s immune cells outside the body using carbon nanotube-polymer composites; the immune cells […]

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Early Quasars Got a “Super Boost” from Star Clusters

August 12, 2014

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Analysis Shows That Early Quasars Got a Super Boost from Large Reservoirs of Gas

New research form Yale University and the Weizmann Institute shows that early quasars took in a “super boost,” feasting from large reservoirs of gas that were part of early star clusters. The universe’s oldest, brightest beacons may have gorged themselves in the dense, cold, gas flows of the early cosmos — creating a kind of […]

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New Drug Compound Reverses the Brain Deficits of Alzheimer’s Disease in Mice

August 6, 2014

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Researchers Reversed the Effects of Alzheimers Disease in Mice

A newly published study reveals a new drug compound that inhibits the negative effects of a protein called STtriatal-Enriched tyrosine Phosphatase and reverses the brain deficits of Alzheimer’s disease in mice. Researchers at Yale School of Medicine have discovered a new drug compound that reverses the brain deficits of Alzheimer’s disease in an animal model. […]

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Researchers Find Clues to Preventing Weight Gain

August 5, 2014

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Researchers Find Clues to Preventing Weight Gain

A new study from Yale University shows that when the researchers blocked the effects of the nuclear receptor PPARgamma in a small number of brain cells in mice, the animals ate less and became resistant to a high-fat diet. Preventing weight gain, obesity, and ultimately diabetes could be as simple as keeping a nuclear receptor […]

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Yale Researchers Discover Glucose ‘Control Switch’ Linked to Diabetes

July 29, 2014

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Researchers Pinpoint Glucose Control Switch That is Key to Diabetes

Yale School of Medicine researchers have discovered that the prolyl endopeptidase enzyme is key to sensing glucose levels in the blood, linking it to both type 1 and type 2 diabetes. Researchers at Yale School of Medicine have pinpointed a mechanism in part of the brain that is key to sensing glucose levels in the […]

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Yale Researchers Discover New Cancer Cell Vulnerability

July 21, 2014

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Researchers Discover New Cancer Cell Vulnerability

New research from Yale University found that simultaneous inhibition of both telomerase and p21 inhibited tumor growth in mice. Yale School of Medicine and Yale Cancer Center researchers have uncovered a genetic vulnerability of cancer cells that express telomerase — an enzyme that drives their unchecked growth — and showed that telomerase-expressing cells depend upon […]

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