A new study found that non-inherited mutations account for many heart defects, suggesting that common pathways may underlie a wide range of common congenital diseases. New mutations that are absent in parents but appear in their offspring account for at least 10% of severe congenital heart disease, reveals a massive genomics study led by researchers [...]

By adding a squaraine dye into polymer solar cells that are based on Forster resonance energy transfer, Yale scientists achieved a 38 percent increase in power conversion efficiency, opening up a new avenue for the development of high-efficiency polymer solar cells. For some solar cells, the future may be fluorescent. Scientists at Yale have improved [...]

Scientists from Yale and UCL have identified a new mechanism that regulates VEGFR2 transport in vascular cells, opening new therapeutic opportunities for developing drugs to stimulate or inhibit blood vessel formation. Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after [...]

Scientists from the Yale School of Medicine, with research collaborators at the MIND Institute, have found that abnormal placental folds and abnormal cell growths called trophoblast inclusions are key markers to identify newborns that are at risk for autism. Researchers at the Yale School of Medicine have figured out how to measure an infant’s risk [...]

A newly published study from Yale University looks at longhorn beetle Rhagium inquisitor and its ability to supercool to below -25°C, examining the unusual structure of its antifreeze protein. In 2011, Yale undergraduates asked a question: How does a Siberian beetle survive some of the cruelest winters on earth? Their answer appears on the cover [...]

In a new study, Yale scientists describe the use of photons for a quantum computer’s memory, creating an artificial medium in which photons repel photons, allowing for efficient, non-destructive encoding and manipulation of quantum information. Scientists at Yale University have found a new way to manipulate microwave signals that could aid the long-term effort to [...]

Researchers at the Yale School of Medicine have discovered that hunger-spiking neurons could help control autoimmune diseases, unmasking a previously unsuspected role of hypothalamic feeding circuits in the regulation of adaptive immune response. Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections [...]

In a newly published study, researchers have demonstrated a new “enabling technology” that uses a class of chemicals called Lewis acids to help transform carbon dioxide into acrylate, a valuable commodity chemical used to make many everyday items. Providence, Rhode Island (Brown University) — A key advance, newly reported by chemists from Brown and Yale [...]

While working with mice, researchers discovered key molecules that switch on stress pathways in preterm lung disorders and potential new drug targets to treat or prevent human BPD. Researchers at Yale School of Medicine have made major discoveries that could lead to new treatments for lung disorders in premature babies. In a mouse study, the [...]

In a newly published study, engineers synthesize a platinum-free catalyst for use in alkaline fuel cells, showing that silver-palladium multi-walled carbon nanotubes are almost as effective as platinum in low-temperature fuel cells. Researchers at Yale University have taken another step toward the development of low-temperature, lower-cost alkaline fuel cells, which are battery-like devices that convert [...]

In a newly published study, Yale University researchers detail how they engineered a system that tricks bacteria to deliver a safer vaccine, which could be used to combat cancer as well as a wide variety of infectious diseases. Vaccines that employ weakened but live pathogens to trigger immune responses have inherent safety issues but Yale [...]

By suppressing the Nogo Receptor 1 gene (NgR1) in older mice, scientists at Yale University have reset their brain to adolescent levels of plasticity, recreating a youthful brain that enables both learning and healing. The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap [...]