A global team of scientists has fully sequenced the Y chromosome, enhancing our understanding of male development, fertility, and genetically-linked diseases. The chromosome associated with…
The Telomere-to-Telomere consortium has fully sequenced the Y chromosome, uncovering 41 new genes and adding 30 million new bases to the human genome. This breakthrough…
A recent study from Yale indicates that additional chromosomes in cancer cells are essential for the growth of tumors. Removing these extra chromosomes inhibits tumor…
New sequence reveals genomic factors in fertility, including sperm production. An international research team has generated the first truly complete sequence of a human Y chromosome,…
Two protein complexes play key but different roles in silencing one X chromosome in female mammals. RIKEN researchers have shed new light on the roles…
Chromosomes are organized into loops that regulate genetic information processing, and these loops are extruded by SMC protein complexes like condensin and cohesin. The DNA-binding…
For a long time, it has been known that viral infections can be more severe in males than females, but the question as to why…
Scientists reveal the results of a controlled clinical trial for a new drug to treat X-linked adrenoleukodystrophy. X-ALD is the most prevalent of the approximately…
A Geisinger study has uncovered that individuals with supernumerary sex chromosome aneuploidy, a condition characterized by an extra X or Y chromosome, are at a…
University of California, Davis scientists help reveal the genome of the common ancestor of all mammals From a platypus to a blue whale, all living…
Chromosome manipulation in live cells indicates that they are fluid. Researchers from CNRS, the Curie Institute, and Sorbonne University have successfully physically acted on chromosomes in live…
Researchers engineer the first sustainable chromosomal alterations in mice. In nature, evolutionary chromosomal changes may take a million years, but scientists have recently reported a novel…
Why is it so hard for humans to have a baby? A new study by a researcher at the Milner Center for Evolution at the…
Analysis of the genome and proteome shows that eukaryotic evolution gave rise to the regulatory function of chromatin. Two meters of DNA must fit into…
Most mammals, including humans, have two sex chromosomes, X and Y. One sex chromosome is usually inherited from each parent, and they pair up as…
A new study finds the clusters form small, stable droplets and may give the genome a gel-like structure. A cell stores all of its genetic…
Combining lab data with supercomputing power reveals role of RNA and chromosome structure in regulating gene expression. Using supercomputer-driven dynamic modeling based on experimental data,…
A study from a team of Massachusetts General Hospital (MGH) investigators points toward a potential strategy for treating X-linked disorders – those caused by mutations…
