Loops, Flags and Tension in DNA
Chromosomes are organized into loops that regulate genetic information processing, and these loops are extruded by SMC protein complexes like condensin and cohesin. The DNA-binding…
Chromosomes are organized into loops that regulate genetic information processing, and these loops are extruded by SMC protein complexes like condensin and cohesin. The DNA-binding…
For a long time, it has been known that viral infections can be more severe in males than females, but the question as to why…
Scientists reveal the results of a controlled clinical trial for a new drug to treat X-linked adrenoleukodystrophy. X-ALD is the most prevalent of the approximately…
A Geisinger study has uncovered that individuals with supernumerary sex chromosome aneuploidy, a condition characterized by an extra X or Y chromosome, are at a…
University of California, Davis scientists help reveal the genome of the common ancestor of all mammals From a platypus to a blue whale, all living…
Chromosome manipulation in live cells indicates that they are fluid. Researchers from CNRS, the Curie Institute, and Sorbonne University have successfully physically acted on chromosomes in live…
Researchers engineer the first sustainable chromosomal alterations in mice. In nature, evolutionary chromosomal changes may take a million years, but scientists have recently reported a novel…
Why is it so hard for humans to have a baby? A new study by a researcher at the Milner Center for Evolution at the…
Analysis of the genome and proteome shows that eukaryotic evolution gave rise to the regulatory function of chromatin. Two meters of DNA must fit into…
Most mammals, including humans, have two sex chromosomes, X and Y. One sex chromosome is usually inherited from each parent, and they pair up as…
A new study finds the clusters form small, stable droplets and may give the genome a gel-like structure. A cell stores all of its genetic…
Combining lab data with supercomputing power reveals role of RNA and chromosome structure in regulating gene expression. Using supercomputer-driven dynamic modeling based on experimental data,…
A study from a team of Massachusetts General Hospital (MGH) investigators points toward a potential strategy for treating X-linked disorders – those caused by mutations…
Researchers from Yale University have identified how the molecule DNA2 helps begin the complex process of repairing breaks in DNA that can cause chromosome rearrangements…
In a newly published study, researchers show how Down syndrome and low SNX27 are connected, discovering that the extra chromosome inherited in Down syndrome impairs…
Inducing cells to express telomerase, the enzyme which is supposed to slow down the metabolic clock, has enabled researchers boost the lifespan of mouse by…
The Tomato Genomics Consortium fully sequenced the genome of the tomato, Solanum Lycopersicum. They report in the Journal Nature that tomatoes possess some 35,000 genes…
Geneticists at Harvard Medical School have discovered how a deletion in one gene from one parent, called a “hemizygous” deletion, can contribute to cancer, suggesting…