How High-Fat Diets Allow Cancer Cells To Go Unnoticed by the Immune System
The immune system relies on cell surface tags to recognize cancer cells. CSHL researchers discovered mice who ate high-fat diets produced less of these tags…
Cold Spring Harbor Laboratory
The Secret History of Corn – And Its “Jumping Genes” – Revealed in Its Genome
Humans adapt through language and culture, passing down knowledge from one generation to the next. Corn plants can’t talk, so they solve the problem of…
Reversing a Genetic Cause of Poor Stress Tolerance
Everyone faces stress occasionally, whether in school, at work, or during a global pandemic. However, some cannot cope as well as others. In a few…
Predicting Effects of Genetic Mutations: For Tomato Genes, One Plus One Doesn’t Always Make Two
Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations — mutations —…
iGenomics: The World’s First DNA “Tricorder” in Your Pocket
Cold Spring Harbor Laboratory (CSHL) scientists developed the world’s first mobile genome sequence analyzer, a new iPhone app called iGenomics. By pairing an iPhone with…
Algorithm Developed to Predict the Evolution of Genetic Mutations
Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see…
Are Overactive Immune Cells the Cause of COVID-19 Deaths?
New publication links neutrophil infiltration in the lungs of patients to COVID-19 symptoms. In the urgent battle to treat COVID-19 patients, a group of eleven…
New Look at Mysterious Large Holes in Cells Involved in Taste, Alzheimer’s, Asthma
Many cells are covered with mysterious large holes, pores that have been associated with the sense of taste as well as Alzheimer’s disease, depression, and…
The Brain Balances Pleasure and Pain – Here’s How
As our brains take in information about the world and use it to steer our actions, two key principles guide our choices: seek pleasure and…
New Tomato Ideal for Urban Gardens and Even Outer Space Created Through Genetic Editing
Genetic editing is moving tomato crops from the field to the city skyline, or even outer space. Researchers used CRISPR gene editing to optimize tomatoes…
Neural Activity Differences Between an Expert’s Brain and a Novice’s
When mice learn to do a new task, their brain activities change over time as they advance from ‘novice’ to ‘expert.’ The changes are reflected…
When Mutant Cells Team Up, an Even Deadlier Blood Cancer Emerges [Video]
Sometimes the whole is greater than the sum of its parts. Researchers at Cold Spring Harbor Laboratory have discovered that two cell mutations, already harmful…
New Brain Research Could Change How Concussions and Other Traumatic Brain Injuries Are Treated
Traumatic brain injuries (TBI), including concussions, can be caused by anything from sports injuries to battlefield trauma. And they can have fatal or lasting effects….
Neuroscientist: Animal Brains Key for Next Generation of Artificial Intelligence
CSHL neuroscientist Anthony Zador shows how evolution and animal brains can be a rich source of inspiration for machine learning, especially to help AI tackle…
Researchers Develop New Method to Identify Splicing-Based Biomarkers for Liver Cancer
Because liver cancer is particularly diverse, genetically, and prone to relapse, identifying biomarkers that can predict disease progression is a critical goal in the fight…