CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology that allows scientists to edit parts of the genome by removing, adding, or altering sections of the DNA sequence. It is simpler, more efficient, and more versatile than earlier forms of genetic editing, making it a powerful tool for genetic research and applications. CRISPR has various applications, including treating and preventing the spread of diseases, improving crops, and potentially correcting genetic defects. The technology is based on a natural system used by bacteria to protect against viruses, adapted for use in other organisms.
A groundbreaking study reveals a new regulatory mechanism in phage proteins, opening new avenues for understanding bacterial defense mechanisms and developing phage-based therapies. A surprising…
SeekRNA enhances gene editing with greater precision and simpler application than CRISPR, promising broader and more effective genetic interventions. Researchers from the University of Sydney…
Research teams have successfully regenerated mouse brain circuits using rat stem cells, showcasing a new method for restoring brain function and studying interspecies brain development….
Researchers optimized sugarcane’s leaf angle using CRISPR gene editing, enhancing its sunlight absorption. Sugarcane ranks as the top crop globally in terms of biomass yield,…
Researchers from the Innovative Genomics Institute at the University of California, Berkeley (UCB) have successfully increased gene expression in a food crop by altering its…
Scientists have increased oil production in Camelina sativa by 21.4% by gene-editing the TT8 gene, paving the way for more efficient biofuel crops. As initiatives…
KAUST researchers have improved CRISPR gene editing safety by reducing harmful DNA deletions and enhancing repair mechanisms, advancing towards safer genetic treatments. A simple and…
Mass Eye and Ear-led phase 1/2 trial, which included 14 participants, found that the first-of-its-kind experimental treatment was safe and efficacious. BRILLIANCE trial results showed…
A study from the Hackett group at EMBL Rome led to the development of a powerful epigenetic editing technology, which unlocks the ability to precisely…
CRISPR gene editing shows potential in treating blindness, with 79% of trial participants experiencing improved vision. About 79% of clinical trial participants experienced measurable improvement…
Princeton scientists make a major improvement to a CRISPR-based gene-editing tool called “prime editing.” Through years of engineering gene-editing systems, researchers have developed a suite…
Retrotransposons can insert new genes into a “safe harbor” in the genome, complementing CRISPR gene editing. The recent greenlighting of a CRISPR-Cas9 treatment for sickle…
New technology using CRISPR to enhance the immune system’s ability to detect cancer cells has been created, potentially paving the way for innovative cancer treatment…
Antibody-targeted ‘enveloped delivery vehicles’ selectively edit T-cells to create CAR T-cells. Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells…
A CRISPR-based platform has discovered numerous genes with the potential to enhance T-cell therapies for cancer treatment. Researchers at Duke University have advanced CRISPR technologies…
New research reveals that CRISPR-Cas9 gene editing can unintentionally lead cancer cells to remove crucial genes, impacting cancer research and treatment strategies. A new study…
Researchers led by Osaka University develop a new gene modification technique known as NICER that significantly reduces off-target mutations in DNA. The gene editing technique…
New findings from a clinical trial, recently published in the New England Journal of Medicine, suggest that stem cell gene therapy could be a potential…