Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly…
Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more…
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic. Since the start of…
CRISPR is a gene-editing tool that has enabled researchers to study the function of different genes in model organisms. Scientists at the Stowers Institute for…
Cryo-EM captures CRISPR-Cas9 base editor in action. Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene…
Scientists Use CRISPR Technology to Insert Sex-Determining Gene. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was…
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences. In nature, bacteria use CRISPR as an adaptive immune system to…
Researchers from the group of Hans Clevers have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used…
Field trials in the Northwest and Southwest show that poplar trees can be genetically modified to reduce negative impacts on air quality while leaving their…
Genetic editing is moving tomato crops from the field to the city skyline, or even outer space. Researchers used CRISPR gene editing to optimize tomatoes…
New method unmasks all DNA changes caused by CRISPR in two days vs. two months; Most errant edits may be harmless, but insights essential to…
CRISPR: More than just for gene editing? Researcher finds new use for revolutionary gene-splicing tool; Electrochemical CRISPR platform could lead to quick blood test for…
The human genome contains regions that “code” for proteins, which means they have instructions to make protein molecules with specific functions in the body. But…
The gene editing technology CRISPR has prompted both breathless predictions of medical breakthroughs and warnings of apocalypse. Yale Insights asked Dr. Greg Licholai, a biotech…
Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a…
Using a gene editing technique known as CRISPR/Cas9, scientists have shown that inactivating the gene FREP1 reduces mosquitos’ susceptibility to infection with Plasmodium, a genus…
Fragile X syndrome is the most frequent cause of intellectual disability in males, affecting one out of every 3,600 boys born. The syndrome can also…
The network of factors behind height is becoming clearer, thanks to the work of Harvard scientists. Led by Associate Professor of Human Evolutionary Biology Terence…