DNA Origami Used to Monitor CRISPR Gene Targeting
CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes. To watch CRISPR enzymes respond to different genes,…
CRISPR
Using CRISPR Genetic Technology to Catch Cancer in the Act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time. When cancer is confined to one…
Scientists Develop New Gene Therapy Strategy to Delay Aging and Extend Lifespan
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic…
New COVID-19 Test Uses a Smartphone Camera and CRISPR Genetic Technology
Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you…
CRISPR-LICHT: A Groundbreaking New Genetic Screening Tool for Human Organoids
Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly…
CRISPR Meets Pac-Man: Powerful New DNA Tool Enables Bigger Gene Edits
Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more…
MIT’s New CRISPR-Based Rapid Test for COVID-19 Shows Improved Sensitivity
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic. Since the start of…
Scientists Use CRISPR to Target Gene Messages Involved in Early Development
CRISPR is a gene-editing tool that has enabled researchers to study the function of different genes in model organisms. Scientists at the Stowers Institute for…
Powerful DNA Manipulation: Improved Gene Editing With New Understanding of CRISPR-Cas9 Tool
Cryo-EM captures CRISPR-Cas9 base editor in action. Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene…
Meet Cosmo, a Bull Calf Genetically Designed to Produce 75% Male Offspring
Scientists Use CRISPR Technology to Insert Sex-Determining Gene. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was…
Nature-Inspired CRISPR Enzyme Discoveries Vastly Expand Genome Editing
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences. In nature, bacteria use CRISPR as an adaptive immune system to…
CRISPR-HOT: New Genetic Tool Can Label Specific Genes and Cells
Researchers from the group of Hans Clevers have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used…
Poplar Trees Were Genetically Modified to Not Harm Air Quality – Here’s What Happened in Testing
Field trials in the Northwest and Southwest show that poplar trees can be genetically modified to reduce negative impacts on air quality while leaving their…
New Tomato Ideal for Urban Gardens and Even Outer Space Created Through Genetic Editing
Genetic editing is moving tomato crops from the field to the city skyline, or even outer space. Researchers used CRISPR gene editing to optimize tomatoes…
New Tool for Rapidly Analyzing CRISPR Edits Reveals Frequent Unintended DNA Changes
New method unmasks all DNA changes caused by CRISPR in two days vs. two months; Most errant edits may be harmless, but insights essential to…
Researcher Finds New Use for Revolutionary Gene-Splicing Tool CRISPR
CRISPR: More than just for gene editing? Researcher finds new use for revolutionary gene-splicing tool; Electrochemical CRISPR platform could lead to quick blood test for…
Scientists Discover Several Protein-Coding Genes That Were Misidentified
The human genome contains regions that “code” for proteins, which means they have instructions to make protein molecules with specific functions in the body. But…
CRISPR’s Potential and Dangers: Is CRISPR Worth the Risk?
The gene editing technology CRISPR has prompted both breathless predictions of medical breakthroughs and warnings of apocalypse. Yale Insights asked Dr. Greg Licholai, a biotech…