Nature-Inspired CRISPR Enzyme Discoveries Vastly Expand Genome Editing
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences. In nature, bacteria use CRISPR as an adaptive immune system to…
CRISPR
CRISPR-HOT: New Genetic Tool Can Label Specific Genes and Cells
Researchers from the group of Hans Clevers have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used…
Poplar Trees Were Genetically Modified to Not Harm Air Quality – Here’s What Happened in Testing
Field trials in the Northwest and Southwest show that poplar trees can be genetically modified to reduce negative impacts on air quality while leaving their…
New Tomato Ideal for Urban Gardens and Even Outer Space Created Through Genetic Editing
Genetic editing is moving tomato crops from the field to the city skyline, or even outer space. Researchers used CRISPR gene editing to optimize tomatoes…
New Tool for Rapidly Analyzing CRISPR Edits Reveals Frequent Unintended DNA Changes
New method unmasks all DNA changes caused by CRISPR in two days vs. two months; Most errant edits may be harmless, but insights essential to…
Researcher Finds New Use for Revolutionary Gene-Splicing Tool CRISPR
CRISPR: More than just for gene editing? Researcher finds new use for revolutionary gene-splicing tool; Electrochemical CRISPR platform could lead to quick blood test for…
Scientists Discover Several Protein-Coding Genes That Were Misidentified
The human genome contains regions that “code” for proteins, which means they have instructions to make protein molecules with specific functions in the body. But…
CRISPR’s Potential and Dangers: Is CRISPR Worth the Risk?
The gene editing technology CRISPR has prompted both breathless predictions of medical breakthroughs and warnings of apocalypse. Yale Insights asked Dr. Greg Licholai, a biotech…
CRISPR-Based Treatment Restores Retinal Function in Mice
Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a…
Gene Editing Technique Suppresses Malaria Infection in Mosquitoes
Using a gene editing technique known as CRISPR/Cas9, scientists have shown that inactivating the gene FREP1 reduces mosquitos’ susceptibility to infection with Plasmodium, a genus…
First Direct Evidence That Fragile X Syndrome Neurons Can Be Restored
Fragile X syndrome is the most frequent cause of intellectual disability in males, affecting one out of every 3,600 boys born. The syndrome can also…
Harvard Study Identifies Genetic ‘Switches’ That Affect Height
The network of factors behind height is becoming clearer, thanks to the work of Harvard scientists. Led by Associate Professor of Human Evolutionary Biology Terence…
Geneticists Show Temperature Change Makes Gene-Editing More Efficient
By modifying a single variable, temperature, Yale geneticists have expanded the potential uses of a groundbreaking gene-editing technology. The CRISPR-Cpf1 gene-editing technology has proved to…
MIT Develops New Model To Speed Up Colon Cancer Research
By delivering RNA encapsulated in lipid nanoparticles to the colon, scientists at MIT have developed a fast and accurate way to speed up colon cancer…
Bioengineers Develop a New System for Human Genome Editing
A team of scientists from MIT, Harvard and Wageningen University have developed a new system for human genome editing that has potential to increase the…