Proof-of-principle research shows that genes can be accurately edited in cells throughout the body. Researchers at the University of California San Diego have laid the…
KSQ Therapeutics uses technology created at MIT to study the role of every human gene in disease biology. CRISPR’s potential to prevent or treat disease…
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged. Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized…
CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes. To watch CRISPR enzymes respond to different genes,…
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time. When cancer is confined to one…
Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic…
Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you…
Many of the fundamental principles in biology and essentially all pathways regulating development were identified in so-called genetics screens. Originally pioneered in the fruit fly…
Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more…
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic. Since the start of…
CRISPR is a gene-editing tool that has enabled researchers to study the function of different genes in model organisms. Scientists at the Stowers Institute for…
Cryo-EM captures CRISPR-Cas9 base editor in action. Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene…
Scientists Use CRISPR Technology to Insert Sex-Determining Gene. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was…
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences. In nature, bacteria use CRISPR as an adaptive immune system to…
Researchers from the group of Hans Clevers have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used…
Field trials in the Northwest and Southwest show that poplar trees can be genetically modified to reduce negative impacts on air quality while leaving their…
Genetic editing is moving tomato crops from the field to the city skyline, or even outer space. Researchers used CRISPR gene editing to optimize tomatoes…
New method unmasks all DNA changes caused by CRISPR in two days vs. two months; Most errant edits may be harmless, but insights essential to…