Revolutionizing Cancer Treatment: Key to Prolonging CAR T Cell Life Uncovered
FOXO1 is required for T cell memory and is linked to longer-lasting clinical outcomes in CAR T cell therapy. CAR T cell therapy has transformed…
FOXO1 is required for T cell memory and is linked to longer-lasting clinical outcomes in CAR T cell therapy. CAR T cell therapy has transformed…
A new study conducted by the University of British Columbia reveals a safe path to overcoming food allergies for older children and others who can’t…
By leveraging mutations from cancerous cells, researchers have engineered T cells that are over 100 times more potent against cancer, promising a new era in…
Researchers have engineered T cells with a cancer-derived mutation, boosting their potency against tumors over 100-fold without toxicity, marking a significant advancement in immunotherapy that…
A groundbreaking study shows that mitochondrial DNA mutations are key indicators of a patient’s likelihood to respond to immunotherapy, revolutionizing cancer treatment approaches. Cancer Research…
A study reveals that blocking the PD-L2 protein in senescent cancer cells post-chemotherapy boosts the immune system’s ability to destroy these cells, potentially enhancing chemotherapy’s…
Research shows B4GALT3 deficiency in mice slows tumor growth and alters immune responses, suggesting new cancer treatment strategies. An old campaign slogan for cough syrup,…
Recent findings at Cold Spring Harbor Laboratory (CSHL) shine a new light on pancreatic cancer. Cold Spring Harbor Laboratory researchers have uncovered that pancreatic cancer…
A More Effective Experimental Design for Engineering a Cell Into a New State MIT and Harvard researchers have developed a novel computational technique that can…
The small molecule, now in clinical trials, increases activity of immune cells and sensitivity of tumors to immune attack. Cancer immunotherapy drugs called PD-1 inhibitors…
Researchers in Western Switzerland have uncovered how to enhance the tumor-fighting abilities of CAR-T cells, artificial immune “super-cells” utilized in battling blood cancers. Among available…
The findings could help doctors identify cancer patients who would benefit the most from drugs called checkpoint blockade inhibitors. Cancer drugs known as checkpoint blockade…
New research sheds light on the molecular processes determining the responsiveness of certain cancers to immunotherapy. A new study has shed light on why immunotherapy…
Understanding of molecular basis of cancer could pave the way for novel treatments. Researchers have conducted an in-depth study on the proteins involved in various…
Immunotherapy is a cancer treatment approach that leverages the body’s natural immune defenses to target tumor cells. While much focus has been on engaging T-cells…
A cross-disciplinary group of scientists at the Otto-von-Guericke University in Magdeburg has unveiled a new understanding of how inflammatory mediators of pathogen defense can remotely…
New recent research from Yale has discovered a method to control the self-destructive tendencies of certain killer T cells utilized in cancer therapy. CAR T-cell…
The results, which have been published in the journal Nature Chemical Biology, lay the groundwork for the future development of unique vaccines and immunotherapies. Amino…