Mutation Mystery Solved: Why Lung Cancer Treatments Often Fail in Non-Smokers
Researchers have discovered the reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked….
Lung cancer is one of the most common and serious types of cancer, characterized by the uncontrolled growth of abnormal cells in one or both lungs, typically in the cells lining the air passages. The abnormal cells do not develop into healthy lung tissue; instead, they divide rapidly and form tumors that can interfere with the functioning of the lung, which can make it difficult to breathe and spread to other parts of the body. There are two main types of lung cancer: non-small cell lung cancer (NSCLC), which is the most common and includes adenocarcinoma, squamous cell carcinoma, and large cell carcinoma, and small cell lung cancer (SCLC), which is less common but more aggressive and likely to spread quickly. The primary cause of lung cancer is smoking, although non-smokers can also develop lung cancer, often due to exposure to radon gas, secondhand smoke, or other environmental factors. Symptoms may include coughing, chest pain, weight loss, and shortness of breath. Treatment options vary depending on the type and stage of cancer and may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these. Early detection significantly improves the effectiveness of treatment and the overall prognosis.
Researchers have discovered the reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked….
A significant study finds that ex-smokers using e-cigarettes have a higher risk of lung cancer and mortality compared to non-users, emphasizing the dangers of vaping…
Technique employs patient’s own cells as a Trojan horse to deliver cancer-destroying medications directly to tumors. While lung cancer may not be the most common…
The diagnostic, which requires only a simple urine test to read the results, could make lung cancer screening more accessible worldwide. Using a new technology…
Sometimes, lung tumors known as adenocarcinomas develop resistance to treatments that were initially successful, undergoing a transformation into a more aggressive form of cancer called…
Columbia Biomedical Engineer Ke Cheng has developed a technique that uses inhalation of exosomes, or nanobubbles, to directly deliver IL-12 mRNA to the lungs of…
Phase II trial finds durvalumab plus ceralasertib boosted immune response and improved outcomes in patients with lung cancer. A specific combination of targeted therapy and…
The findings could lead to the development of a new anti-cancer drug and more personalized lung cancer treatment. A new study by Tulane University has…
A Mount Sinai study found that blocking an allergy pathway boosts antitumor immunity in lung cancer, with an allergy drug, dupilumab, enhancing the effectiveness of…
Research shows increased lung cancer rates in British and Australian naval personnel due to asbestos exposure, highlighting the ongoing risks of asbestos and the need…
Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis…
Researchers at the Keck School of Medicine of USC found that a key protein can move to the nucleus of cancer cells when they are…
A tiny robot that can travel deep into the lungs to detect and treat the first signs of cancer has been developed by researchers at…
The findings indicate that the state of an individual’s mental health during diagnosis plays a crucial role in their overall health. According to a recent…
Weill Cornell Medicine researchers have identified a protein, XBP1s, in lung cancer cells that aids tumor survival by suppressing neighboring immune cells’ anti-cancer abilities. This…
Study reports five-year survival outcomes. Patients with resectable non-small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall…
Using a mouse model, Japanese researchers unleash the likely mechanism of action of Actinidia arguta (sarunashi) juice on lung cancer development. Lung cancer is a…
Scientists have identified new cancer treatment targets. In Switzerland, cancer is the second-leading cause of death. Non-small cell lung cancer (NSCLC) is the cancer form…