Browsing: Metastisis

Metastasis is the process by which cancer cells spread from the original (primary) tumor site to other parts of the body, forming new (secondary) tumors. This is a hallmark of cancer malignancy and is responsible for the majority of cancer-related deaths. Metastasis occurs in a multi-step process that includes cancer cells detaching from the original tumor, invading the surrounding tissue, entering the bloodstream or lymphatic system, and then migrating to distant sites. Once at a new location, these cells can colonize and form new tumors, which often complicates treatment options and significantly worsens the prognosis.

The ability of cancer cells to metastasize depends on numerous factors including the genetic makeup of the cancer cells, interactions with the body’s immune system, and the characteristics of the non-cancerous cells that surround tumors. Understanding the mechanisms of metastasis is critical for developing targeted therapies that can prevent or treat this devastating aspect of cancer. Researchers continue to explore ways to block the metastatic process or to treat metastatic cancer more effectively.